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Recruiting NCT04252989

Atropine 0.01% Eyedrops for Evolutive Myopia Treatment in Children

Observational Myopia Children

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: data collection.
Who it may be relevant to
Registry conditions: Myopia, Children. Basic parameters: up to 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Atropine 0.01% Eyedrops for Evolutive Myopia Treatment in Children. MYOPSTOP

Overview

Prevalence of myopia and its complications has been increasing over the past decades, especially among children and adolescents. It reaches record levels in Asia: nearly 80% of the population in some regions in 2012 where the investigators speak in terms of epidemic. ATROPINE 0.01% eyedrops one drop per day is today an evolutive myopia treatment, whose results are promising. The investigators use this eye drops in our clinical practice at hospital of Saint-Etienne since 2017. Few clinical data have been published so far concerning the French population. The investigators would like to build a database so that the investigators can publish our results and share our experience.

Interventions

  • Other data collection
    * Demographic data: age, sex * Ophthalmological history: refraction of parents, previous refractions * Ophthalmological data at each examination: intra-ocular pression, objective refraction after "fog", cycloplegia with SKIACOL, slit lamp, dilated eye exam, biometrics * Potential undesirable events (halos, photophobia...)

Primary outcome measures

  • previous refractions [Time frame: every 6 months up to age 18 years]
  • refraction of parents [Time frame: every 6 months up to age 18 years]
  • intra-ocular pression [Time frame: every 6 months up to age 18 years]
  • objective refraction after "fog" [Time frame: every 6 months up to age 18 years]
  • cycloplegia with SKIACOL [Time frame: every 6 months up to age 18 years]
  • slit lamp [Time frame: every 6 months up to age 18 years]
  • dilated eye exam [Time frame: every 6 months up to age 18 years]
  • biometrics [Time frame: every 6 months up to age 18 years]
Secondary outcome measures (1)
  • undesirable events collection [Time frame: every 6 months up to age 18 years]

Eligibility criteria

Inclusion criteria

  • Children with active myopia treated with ATROPINE 0.01% eye drops
  • patient affiliated with a social security organization
  • agreement of both parents

Exclusion criteria

  • non compliance with treatment

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

France · 1 center
  • CHU de Saint Etienne — Saint-Etienne

Identifiers

NCT: NCT04252989 · IRBN962019/CHUSTE

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗