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Recruiting NCT04237701

Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System

Observational Heart Failure Heart Failure With Reduced Ejection Fraction Heart Failure With Preserved Ejection Fraction Heart Failure NYHA Class IV

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Preserved Ejection Fraction, Heart Failure NYHA Class IV. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Retrospective and Real-Time Monitoring of Heart Failure Across the Yale New Haven Health System Via a Live Registry

Overview

The Yale HF Registry is a live EHR based registry that allows for retrospective and real-time monitoring of Heart Failure case across the Yale New Haven Health System.

Detailed description

Electronic Health Records based registries can be an important resource for precision medicine delivery by understanding the population burden of chronic diseases such as heart failure. These registries can allow for a deeper understanding of gaps in guideline recommended therapies among patients who are under the purview of large, integrated Therefore, we have created a live registry within the integrated Yale New Haven Health System-the Yale Heart Failure Registry-that includes all patients with a diagnosis of HF and has detailed information about demographics, comorbidities, laboratories, imaging, medications, and clinical outcomes (including hospital readmissions). The registry is updated daily and can be queried for clinically relevant questions aimed at quality improvement.

Primary outcome measures

  • Number of participants hospitalized for heart failure [Time frame: 10 years]
  • Doses of therapies that comprise guideline directed medical therapy [Time frame: 10 years]

Eligibility criteria

Inclusion criteria

  • Seen within the Yale New Haven Health System
  • Diagnosis of heart failure

Exclusion criteria

  • Age<18

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

United States · 1 center
  • Yale New Haven Health System — New Haven

Publications

  • Greene SJ, Fonarow GC, DeVore AD, Sharma PP, Vaduganathan M, Albert NM, Duffy CI, Hill CL, McCague K, Patterson JH, Spertus JA, Thomas L, Williams FB, Hernandez AF, Butler J. Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction. J Am Coll Cardiol. 2019 May 21;73(19):2365-2383. doi: 10.1016/j.jacc.2019.02.015. Epub 2019 Mar 4. PMID 30844480
  • Ahmad T, Desai NR. Reimagining Evidence Generation for Heart Failure and the Role of Integrated Health Care Systems. Circ Cardiovasc Qual Outcomes. 2022 Apr;15(4):e008292. doi: 10.1161/CIRCOUTCOMES.121.008292. Epub 2022 Mar 11. No abstract available. PMID 35272506

Identifiers

NCT: NCT04237701 · 2000026771 · No NIH funding

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗