Status Epilepticus Population Study (STEPS)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: collection of patient data.
- Who it may be relevant to
- Registry conditions: Epileptic Seizures. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The aim of this observational multicenter cohort study is to gain a deeper understanding regarding the effects of treatment adaption based on information from outcome prediction models, risk stratification, as well as treatment monitoring, detection, prevention, and management of complications on course and outcome of adult patients with status epilepticus (SE).
Interventions
- Other collection of patient data
Extract data from the digital medical records, the electroencephalographic and microbiologic database.
Primary outcome measures
- Demographics [Time frame: between 01.01.2005 and 31.12.2023]
- Data from acute prehospital management by the emergency medical services (EMS) [Time frame: between 01.01.2005 and 31.12.2023]
- Duration of ICU (intensive care unit) and hospital stay, and destination at discharge [Time frame: between 01.01.2005 and 31.12.2023]
- Date(s) of seizure(s) captured by electroencephalographic (EEG) data [Time frame: between 01.01.2005 and 31.12.2023]
- Seizure history and etiology [Time frame: between 01.01.2005 and 31.12.2023]
- Number and Duration of SE episodes [Time frame: between 01.01.2005 and 31.12.2023]
- Types of SE [Time frame: between 01.01.2005 and 31.12.2023]
- Additional features of the seizure [Time frame: between 01.01.2005 and 31.12.2023]
- ICU Scoring Systems [Time frame: between 01.01.2005 and 31.12.2023]
- Clinical neurologic monitoring scores [Time frame: between 01.01.2005 and 31.12.2023]
Eligibility criteria
Inclusion criteria
- Adult patients (i.e., patients ≥18 years of age) with diagnosed SE between 2005 and 2023 who have been treated at the University Hospital of Basel or the Cantonal Hospital Aarau.
Exclusion criteria
- Patients younger than 18 years.
- Patients with repetitive epileptic seizures not qualifying for SE.
- Patients with documented refusal of the general consent.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Switzerland · 2 centers
- Cantonal Hospital Aarau (KSA) — Aarau
- Clinic for Intensive Care Medicine, University Hospital Basel — Basel
Publications
- Fisch U, Junger AL, Baumann SM, Semmlack S, De Marchis GM, Ruegg SJ, Hunziker S, Marsch S, Sutter R. Association Between Dose Escalation of Anesthetics and Outcomes in Patients With Refractory Status Epilepticus. Neurology. 2024 Jan 23;102(2):e207995. doi: 10.1212/WNL.0000000000207995. Epub 2023 Dec 15. PMID 38165316
Identifiers
NCT: NCT04204863 · 2019-00693; me19Sutter5