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Not yet recruiting NCT04129073

QUality Of Life and surviVAl in carDIac arreSt Patients

Observational Cardiac Arrest Post-Anoxic Coma Central Nervous System Diseases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Intensive care treatment.
Who it may be relevant to
Registry conditions: Cardiac Arrest, Post-Anoxic Coma, Central Nervous System Diseases. Basic parameters: from 14 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

QUO VADIS - QUality Of Life and surviVAl in carDIac arreSt Patients

Overview

QUO VADIS is a national observational study with the aim to describe clinical intervention and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest

Detailed description

Despite recent improvements in post-resuscitation care, about 50% of patients resuscitated from cardiac arrest die or have poor neurological prognosis. Post-anoxic brain injury is common after cardiac arrest and is a major cause of post-resuscitation mortality. Since there has been a significant investment in improving the emergency response to both in-hospital ad out-of-hospital cardiac arrest (IHCA and OHCA, respectevly) patients and reported improvements in short-term survival outcomes, the long-term neurological state and quality of life of survivors and their caregiver is of growing significance.

QUO VADIS is a national observational study created to describe clinical interventions and utilization of neuroprognostication tools in the management of patients admitted to ICU following cardiac arrest.

The aims of the study are:

* To create an Italian Registry that describes clinical interventions and neuroprognostication tools used in the management of patients admitted to ICU following cardiac arrest * To evaluate, after one year from the cardiac arrest, the neurological outcome and the quality of life of the patients; * To evaluate, after one year from the cardiac arrest, the quality of life of caregivers; * To identify the most effective clinical intervention in the management of post-cardiac arrest patients admitted to ICU; * To create a prognostic model for patients admitted to ICU after cardiac arrest.

Interventions

  • Other Intensive care treatment
    Intensive care treatment; Utilization of neuroprognostication tools

Primary outcome measures

  • Disability [Time frame: 6 months]
  • Neurological Outcome [Time frame: 6 months]
  • Patients quality of life [Time frame: 12 months]
Secondary outcome measures (1)
  • Caregiver quality of life [Time frame: 12 months]

Eligibility criteria

Inclusion criteria

  • Age ≥ 14 years;
  • Cardiac Arrest within 24 hours ICU admission

Exclusion criteria

  • Absence of Informed consent;
  • Age < 14 years

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT04129073 · QUO VADIS

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗