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Recruiting NCT04118712

Pediatric Ovarian Tissue Banking - Operative Specimens From Females 0-18 Years of Age

Observational Benign Cysts Ovarian Cystectomy Torsion Malignant Cysts Ovarian

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Benign Cysts Ovarian, Cystectomy, Torsion, Malignant Cysts Ovarian. Basic parameters: up to 18 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

A child is eligible to participate in this study because she is having surgery on her ovary. The investigators may obtain a sample of any discarded tissue from the surgery for an ovarian tissue library. This study is being conducted to understand how common ovarian conditions effect the number and quality of ovarian follicles and the reproductive potential of the ovary.

Detailed description

The investigators intend to enroll 100 girls and women in this study who are undergoing surgery involving the ovary. This may include patients with different conditions for comparison, such as ovarian cysts or masses and ovarian torsion. For each patient, the investigators will obtain the discarded tissue from the operating room after the affected ovarian tissue is resected. The tissue sample will only be taken for the tissue library from ovarian tissue that would otherwise be discarded.

No additional tissue will be collected other than that which is already removed as part of the ovarian procedure. No additional surgery or other procedures will be performed for the purposes of this study. The tissue will be assigned a study ID number and the age, gender and diagnosis of the child will be entered on the tissue library log and maintained for the duration of the study.

Primary outcome measures

  • Ovarian Tissue Banking [Time frame: October 2016- December 2030]

Eligibility criteria

Inclusion criteria

  • Pre and Post Pubertal females
  • Ages 0-18 years old
  • Undergoing scheduled or emergent operative procedures involving the ovary
  • oophorectomy (torsion, benign mass/cyst, malignant mass/cyst)
  • ovarian cystectomy

Exclusion criteria

  • Pregnant females

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

United States · 1 center
  • Ann & Robert H Lurie Childrens Hospital — Chicago

Identifiers

NCT: NCT04118712 · 2017-726

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗