Surviving Pneumonia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: No intervention.
- Who it may be relevant to
- Registry conditions: Community-acquired Pneumonia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The study aims to explore risk factors for poor prognosis among patients admitted with community-acquired pneumonia (CAP). During a 5-year study period, all patients (aged ≥ 18 years) admitted with CAP at North Zealand Hospital will be invited for inclusion. Questionnaires, anthropometric measures, laboratory tests, and biomaterials will be collected at admission, daily during admission, at discharge and at follow-up. The main clinical outcomes of the study consist of deaths and development of diabetes.
Interventions
- Other No intervention
Obervational
Primary outcome measures
- Number of death from any causes [Time frame: From date of admission until the day of death from any causes, up to 24 months]
- Number of participants who develop diabetes [Time frame: Up to 24 months]
Secondary outcome measures (3)
- Length of hospital stay [Time frame: Participants will be followed for the duration of hospital stay, an expected average of 5 days]
- Oral glucose tolerance test [Time frame: Day 1, discharge (an average of 5 days), 1 month and 6-month]
- Number of participants who are readmitted [Time frame: Up to 6 months]
Eligibility criteria
Inclusion criteria
- Infiltrate on chest radiograph plus one or more of the following:
- Fever (temperature, ≥38.0°C)
- Hypothermia (<35.0°C),
- New cough with or without sputum production
- Pleuritic chest pain
- Dyspnea
- Altered breath sounds on auscultation.
Exclusion criteria
- Patients unable to give informed consent
- Patients unwilling to give informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Denmark · 1 center
- Department of Pulmonary and Infectious Diseases, Nordsjællands Hospital — Hillerød
Publications
- Ryrso CK, Hegelund MH, Faurholt-Jepsen D, Dungu AM, Ritz C, Olsen MF, Krogh-Madsen R, Lindegaard B. Health-related quality of life in community-acquired pneumonia: a prospective cohort study. Sci Rep. 2026 Jun 23. doi: 10.1038/s41598-026-59119-0. Online ahead of print. PMID 42332204
- Dungu AM, Lundgaard AT, Ryrso CK, Hegelund MH, Jensen AV, Kristensen PL, Krogh-Madsen R, Faurholt-Jepsen D, Ostrowski SR, Banasik K, Lindegaard B. Inflammatory and endothelial host responses in community-acquired pneumonia: exploring the relationships with HbA1c, admission plasma glucose, and glycaemic gap-a cross-sectional study. Front Immunol. 2024 May 22;15:1372300. doi: 10.3389/fimmu.2024.1372 PMID 38840922
- Ryrso CK, Hegelund MH, Dungu AM, Faurholt-Jepsen D, Pedersen BK, Ritz C, Krogh-Madsen R, Lindegaard B. Association between Barthel Index, Grip Strength, and Physical Activity Level at Admission and Prognosis in Community-Acquired Pneumonia: A Prospective Cohort Study. J Clin Med. 2022 Oct 27;11(21):6326. doi: 10.3390/jcm11216326. PMID 36362554
Identifiers
NCT: NCT03795662 · Surviving Pneumonia