Recruiting NCT03770936
Effect of Some Drugs on Liver Fibrosis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Candesartan, Ramipril.
- Who it may be relevant to
- Registry conditions: Liver Fibroses. Basic parameters: from 20 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Clinical Study Evaluating the Efficacy of Renin Angiotensin System Inhibitors on the Extent of Liver Fibrosis in Patients With Chronic Hepatitis C
Overview
Effect of Some Drugs on Liver Fibrosis
Detailed description
The study aimed at evaluating the effect of Some Drugs on Liver Fibrosis
Interventions
- Drug Candesartan
Candesartan 8 mg/day - Drug Ramipril
ramipril 1.25 mg/day
Primary outcome measures
- Change in Fibroscan or APRI score [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- chronic hepatitis C
Exclusion criteria
- Acute hepatitis
- Thalassemia
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Sherief Abd-Elsalam — Tanta
Publications
- Mostafa TM, El-Azab GA, Badra GA, Abdelwahed AS, Elsayed AA. Effect of Candesartan and Ramipril on Liver Fibrosis in Patients with Chronic Hepatitis C Viral Infection: A Randomized Controlled Prospective Study. Curr Ther Res Clin Exp. 2021 Nov 12;95:100654. doi: 10.1016/j.curtheres.2021.100654. eCollection 2021. PMID 34925649
Identifiers
NCT: NCT03770936 · liver fibrosis