Menu
Recruiting NCT03746964

Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm

— Observational Patient With Ascending Aortic Aneurysm With Surgical Indication for Replacement

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cardiac MRI, in-vitro elasticity tests.
Who it may be relevant to
Registry conditions: Patient With Ascending Aortic Aneurysm With Surgical Indication for Replacement. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The biomechanical properties of the aorta are currently poorly understood. A better understanding would optimize surgical indications and monitoring techniques for patients with thoracic aortic aneurysms.

Interventions

  • Procedure Cardiac MRI
    Preoperative cardiac MRI
  • Other in-vitro elasticity tests
    in-vitro elasticity tests performed on a segment of ascending aorta collected during surgery

Primary outcome measures

  • aortic compliance by cardiac MRI [Time frame: Before surgery]
  • In-vitro testing of the elasticity of the aortic wall fragment collected during surgery. [Time frame: through study completion, an average of 12 months]

Eligibility criteria

Inclusion criteria

  • Person who has given oral consent
  • Patient with ascending aortic aneurysm with surgical indication for replacement
  • Age > 18 years old
  • Scheduled surgery

Exclusion criteria

  • Person not affiliated to the national health insurance system
  • Protected adult
  • Pregnant or breastfeeding woman
  • MRI Contraindication
  • Emergency surgical procedure

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

France · 1 center
  • Chu Dijon Bourogne — Dijon

Identifiers

NCT: NCT03746964 · MORGANT 2018 MECATHOR

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗