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Recruiting NCT03725527

Effect of Rectus Sheath Block on Diaphragmatic Function After Elective Upper Abdominal Surgery

No phase Interventional Acute Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Rectus Sheath Block.
Who it may be relevant to
Registry conditions: Acute Pain. Basic parameters: 18 years — 50 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Respiratory Effects of Rectus Sheath Block in Patients Undergoing Major Upper Abdominal Surgery.

Overview

This study will be undertaken to investigate the respiratory and analgesic effects of ultrasound guided rectus sheath block analgesia after elective abdominal surgery with midline incision.

Detailed description

A major proportion of pain experienced by patients undergoing abdominal surgeries is due to somatic pain signals derived from the abdominal wall. The central portion of anterior abdominal wall components (skin, muscles and parietal peritoneum) is innervated by sensory neurons branching from the anterior rami of spinal nerves T7 to T1. These neurons lie between the rectus abdominis muscle and posterior rectus sheath, and pierce the rectus muscle close to the midline. The tendinous intersections of the rectus muscle do not fuse with the posterior rectus sheath, thereby allowing the injectate to spread cephalo-caudally within this potential space. Rectus sheath (RS) block has been described for any midline abdominal incisions (epigastric and umbilical hernia repairs). As visceral pain becomes attenuated by the 2nd postoperative day, rectus sheath block can also be administered for midline laparotomy.

However, the effects of rectus sheath block analgesia on the respiratory function after abdominal surgery with midline incisions are still under investigation.

Interventions

  • Procedure Rectus Sheath Block
    Sonar guided RSB will be performed using a 16-G, 8-cm TuohyUpon reaching this potential space, after careful aspiration.

Primary outcome measures

  • Diaphragmatic inspiratory amplitude during quiet/deep breathing (DIA)/cm [Time frame: 24 hours Postoperative]
Secondary outcome measures (2)
  • Verbal Rating Scale [Time frame: 24 hours Postoperatively]
  • Forced Vital Capacity/L [Time frame: 24 hours Postoperatively]

Eligibility criteria

Inclusion criteria

  • Age: 18-50 years.
  • Sex: both males and females.
  • BMI< 30kg/m2.
  • ASA physical status: 1, II and III.
  • Elective abdominal surgery with midline incisions.

Exclusion criteria

  • Patient refusal.
  • Infection at injection site
  • Coagulation disorders.
  • Allergy to study medications.
  • Pregnancy.
  • Respiratory tract infection within the last 2 weeks.
  • Urgent abdominal surgery

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Assiut university main hospital, ICUs — Asyut

Identifiers

NCT: NCT03725527 · 17100594

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗