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Recruiting NCT03718637

Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)

Phase IV Interventional Tennis Elbow Lateral Epicondylitis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging.
Who it may be relevant to
Registry conditions: Tennis Elbow, Lateral Epicondylitis. Basic parameters: from 18 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Efficacy Evaluation of Surgical Treatment Using Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)

Overview

The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients. A bioinductive patch is an implant that may foster tendon regrowth and healing following surgery. Patients will be randomize into one of two groups: control and investigational. Patients in the "control group" will receive the normal surgery for patients who do not respond to physical therapy, lifestyle changes, and anti-inflammatory treatment. Patients in the "experimental group" will receive the same surgical treatment, with the addition of the bioinductive patch. This patch will be implanted during surgery. Then, using a combination of ultrasound studies and other measures, the investigators will assess how well the patch works compared to surgery alone.

Detailed description

A bioinductive patch is an implant that may foster tendon regrowth and healing following surgery. Patients will be randomized into one of two groups: control and investigational. All surgical patients will have failed non surgery options for 6 months (physical therapy, lifestyle changes, anti-inflammatories, injections) Patients in the "control group" will receive the standard surgery (open lateral epicondylectomy) . Patients in the "experimental group" will receive the same surgical treatment, with the addition of the bioinductive patch. This patch will be implanted during surgery. Then, using a combination of ultrasound studies and other measures, the investigators will assess how well the patch works compared to surgery alone.

Interventions

  • Biological Smith & Nephew Bioinductive Implant
    A bioinductive implant that is supposed to foster healthy tendon regrowth after surgery.
  • Procedure Lateral Epicondylectomy
    This procedure is the standard of care for lateral epicondylitis patients who fail conservative treatment options.
  • Radiation Ultrasound Imaging
    An ultrasound will be performed on each patient both preoperatively and at 6 months.

Primary outcome measures

  • PROMIS CAT Scores [Time frame: Preoperative to 1 year postoperative]
  • Visual Analog Scale (VAS) for Pain [Time frame: Preoperative to 1 year postoperative]
  • Range of Motion [Time frame: Preoperative to 1 year]

Eligibility criteria

Inclusion criteria

  • Diagnosis of lateral epicondylitis (tennis elbow) that has failed conservative treatment (Physical therapy, activity change, anti-inflammatory treatment.

Exclusion criteria

  • Previous surgery on the currently-affected elbow.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • Henry Ford Hospital — Detroit

Identifiers

NCT: NCT03718637 · 12495

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗