Swiss Atrial Fibrillation Pulmonary Vein Isolation Registry
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: catheter-based ablation of atrial fibrillation (pulmonary vein isolation).
- Who it may be relevant to
- Registry conditions: Catheter-based Ablation of Atrial Fibrillation. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Switzerland
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Registry of patients with atrial fibrillation undergoing catheter-based ablation of atrial fibrillation (pulmonary vein isolation) to determine long-term success rates of catheter-based ablation of atrial fibrillation (pulmonary vein isolation) and to evaluate factors associated with long-term success of catheter-based ablation of atrial fibrillation (pulmonary vein isolation).
Interventions
- Procedure catheter-based ablation of atrial fibrillation (pulmonary vein isolation)
catheter-based ablation of atrial fibrillation (pulmonary vein isolation)
Primary outcome measures
- changes in retention rate of normal sinus rhythm after catheter-based ablation of atrial fibrillation (pulmonary vein isolation) [Time frame: before catheter-based ablation of atrial fibrillation and 3, 6 and 12 months after catheter-based ablation of atrial fibrillation]
Secondary outcome measures (2)
- morphologic changes of left cardiac atrium [Time frame: before catheter-based ablation of atrial fibrillation (pulmonary vein isolation)]
- changes in retention rate of normal sinus rhythm after catheter-based ablation of atrial fibrillation (pulmonary vein isolation) [Time frame: 12 months after catheter-based ablation of atrial fibrillation and then at intervals of one year until 2035]
Eligibility criteria
Inclusion criteria
- patients undergoing catheter-based ablation of atrial fibrillation (pulmonary vein isolation)
Exclusion criteria
- Patients not able or willing to participate in this study
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Switzerland · 2 centers
- Cardiology/Electrophysiology, University Hospital Basel — Basel
- University Hospital Bern — Bern
Publications
- Bruss J, Kueffer T, Tanner H, Noti F, Haeberlin A, Thalmann G, Kozhuharov NA, Kovacs B, Spahiu V, Siklody CH, Reichlin T, Roten L. NT-proBNP as a Predictor of Atrial Fibrillation Recurrence After Cryoballoon, Radiofrequency and Pulsed-Field Ablation. Pacing Clin Electrophysiol. 2026 Apr 3. doi: 10.1111/pace.70237. Online ahead of print. PMID 41930479
- Hennings E, Aeschbacher S, Coslovsky M, Paladini RE, Meyre PB, Voellmin G, Blum L, Kastner P, Ziegler A, Conen D, Zuern CS, Krisai P, Badertscher P, Sticherling C, Osswald S, Knecht S, Kuhne M. Association of bone morphogenetic protein 10 and recurrent atrial fibrillation after catheter ablation. Europace. 2023 Jun 2;25(6):euad149. doi: 10.1093/europace/euad149. PMID 37314197
- Meyre PB, Sticherling C, Spies F, Aeschbacher S, Blum S, Voellmin G, Madaffari A, Conen D, Osswald S, Kuhne M, Knecht S. C-reactive protein for prediction of atrial fibrillation recurrence after catheter ablation. BMC Cardiovasc Disord. 2020 Sep 29;20(1):427. doi: 10.1186/s12872-020-01711-x. PMID 32993521
Identifiers
NCT: NCT03718364 · 2018-00226; me18Kuehne2