Uremic Toxins and Outcomes in Chronic Kidney Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Chronic Kidney Diseases. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD
Overview
The aim of this cohort study is: To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
Detailed description
To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.
Primary outcome measures
- all cause mortality [Time frame: 5 years]
Secondary outcome measures (1)
- comorbidities [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- age ≥18 years old;
- clinically diagnosed with chronic kidney disease, according K/DOQI criteria.
Exclusion criteria
- acute kidney injury
- history of kidney injury <3 months
- malignancy
- pregnancy
- incomplete clinical data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- Shanghai Ninth People's Hospital — Shanghai
Identifiers
NCT: NCT03711617 · CKD-toxins