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Recruiting NCT03708627

Bimatoprost as a Treatment for Graves' Orbitopathy

Early Phase I Interventional Graves Ophthalmopathy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Bimatoprost Ophthalmic.
Who it may be relevant to
Registry conditions: Graves Ophthalmopathy. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

The Role of Bimatoprost in Graves' Periorbitopathy

Overview

Testing whether Bimatoprost, a topical eye drop used for glaucoma, can be used to induce periorbital fat atrophy in patients with Graves' disease

Interventions

  • Drug Bimatoprost Ophthalmic
    Bimatoprost, aka Lumigan, one drop in one eye nightly

Primary outcome measures

  • Reduction in periorbital fat causing improvement in proptosis [Time frame: 1 year]

Eligibility criteria

Inclusion Criteria: Graves' Ophthalmopathy with Exophthalmos/Proptosis -

Exclusion Criteria: Active Graves Disease, Currently pregnant, Taking Steroids

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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • University of Washington — Seattle

Identifiers

NCT: NCT03708627 · IRB00294393

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗