Pitch Perception and Memory: Deficits and Training
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Listening tests. Pitch training protocol, visuo-spatial training protocol, EEG/MEG/MRI recordings..
- Who it may be relevant to
- Registry conditions: Cochlear Implants. Basic parameters: 5 years — 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in audio and audio-visual contexts to characterize pitch processing deficits, and test a pitch training program.
Interventions
- Behavioral Listening tests. Pitch training protocol
The two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of \~20 minutes performed at home over a period of 15 weeks. - Behavioral visuo-spatial training protocol
The two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of \~20 minutes performed at home over a period of 15 weeks. - Behavioral EEG/MEG/MRI recordings.
Listening tests. EEG/MEG/MRI recordings
Primary outcome measures
- percentages of correct responses in listening tests [Time frame: during procedure]
- reaction times in listening tests [Time frame: during procedure]
- Event-Related Fields [Time frame: during procedure]
- Oscillations [Time frame: during procedure]
Secondary outcome measures (6)
- percentages of correct responses [Time frame: Day 0]
- percentages of correct responses [Time frame: Day 0]
- reaction times [Time frame: Day 0]
- reaction times [Time frame: Day 0]
- Event-Related Fields [Time frame: Day 0]
- Oscillations [Time frame: Day 0]
Eligibility criteria
Inclusion criteria
For adult participants:
- Aged between 18 and 90
- Absence of neurological and psychiatric disorders
- No major cognitive deficit, ability to understand and apply study instructions
- Motivation to participate efficiently in the study
- Written informed consent to participant in the study
- Affiliated to social security
- Control participants and participants with congenital amusia for Experiment 5: MRI/MEG compatibility
For underage participants:
- Subject aged 5 years and over
- Informed consent of parents or guardians for the participation of the child being studied
- No neurological or psychiatric history
- Without major cognitive impairment and ability to understand and apply setpoint.
- Subject affiliated to a social security scheme
- Motivation to participate effectively in the project
Exclusion criteria
For adult participants:
- Age below 18 or above 90
- Pregnant or breast-feeding woman
For underage participants:
\- Pregnant or nursing minors
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
France · 1 center
- Lyon Neuroscience Research Center — Bron
Identifiers
NCT: NCT03707691 · 69HCL18_0632 · 2018-A02670-55