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Recruiting NCT03664609

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

Observational Parkinson Disease Essential Tremor Dystonia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Deep Brain Stimulation.
Who it may be relevant to
Registry conditions: Parkinson Disease, Essential Tremor, Dystonia. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States, Belgium, France, Germany, Italy +1
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.

Detailed description

The purpose of this study is to characterize

1\. real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.

Interventions

  • Device Deep Brain Stimulation
    Deep Brain Stimulation in patients with Parkinson Disease, Dystonia and Essential Tremor.

Primary outcome measures

  • Mean Change in Unified Parkinson's Disease Rating Scale (UPDRS III) at up to 5 years post implant compared to baseline [Time frame: 5 yrs. post implant]

Eligibility criteria

Inclusion criteria

  • Must be previously treated with or eligible for implantation with a deep brain stimulation system

Exclusion criteria

  • No Exclusion Criteria

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Other

Study locations

United States · 9 centers
  • St. Joseph's Hospital & Medical Center — Phoenix
  • University of California, San Francisco — San Francisco
  • University of Miami Hospital — Miami
  • University of South Florida — Tampa
  • St. Luke's Regional Medical Center — Boise
  • Albany Medical Center — Albany
  • Wake Forest University School of Medicine — Winston-Salem
  • Allegheny General Hospital — Pittsburgh
  • … and 1 more center
Germany · 5 centers
  • Uniklinik Köln — Cologne
  • Universitaetsklinikum Dusseldorf — Düsseldorf
  • Uniklinikum Jena — Jena
  • Universitaetsklinikum Schleswig-Holstein — Lübeck
  • Universitaetsklinikum Wuerzburg — Würzburg
Belgium · 2 centers
  • AZ St. Lucas — Ghent
  • AZ Delta — Roeselare
France · 1 center
  • Hopital Fondation Adolphe de Rothschild — Paris
Italy · 1 center
  • Fondazione Istituto Neurologico Casimiro Mondino — Pavia
Spain · 1 center
  • Hospital Virgen Del Rocio — Seville

Identifiers

NCT: NCT03664609 · A4170

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗