Menu
Recruiting NCT03650010

Total Ankle Replacement: Clinical and Radiological Outcomes

Observational Ankle Arthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Total ankle replacement.
Who it may be relevant to
Registry conditions: Ankle Arthritis. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of Epidemiology and Radiological and Clinical Outcomes in Total Ankle Prosthesis

Overview

This retrospective and prospective study intends to evaluate the epidemiology and effectiveness of ankle joint surgery in patients operated from January 2011 to March 2026, evaluating the results both clinically and radiographically.

Detailed description

The aim of this study is to evaluate radiographically and clinically using clinical and radiographic outcomes . Few studies exist in the literature and rarely report fix-bearing and mobile-bearing prosthetics \[1-4\]. Therefore the data related to this study can be considered a reference in the literature.

Patients who performed and will perform ankle prosthesis surgery from January 2011 to March 2026 and who underwent a clinical evaluation (also using questionnaires and scores) and radiographic evaluation.

The clinical data and radiological parameters were collected together with the visits and the procedures prescribed according to the clinical routine of the department.

Interventions

  • Procedure Total ankle replacement
    total ankle prosthesis through a lateral or an anterior approach

Primary outcome measures

  • Changes in American orthopaedic foot and ankle society (AOFAS) ankle-hindfoot score [Time frame: Pre operatively, 2 months post-operatively, 6 months post-operatively, 12 months post-operatively, 24-36-48-60-72-84-96-108-120 months post-operatively]
  • Changes in Short form 12 (SF 12) [Time frame: Pre operatively, 2 months post-operatively, 6 months post-operatively, 12 months post-operatively, 24-36-48-60-72-84-96-108-120 months post-operatively]
  • Anterior distal tibial angle [Time frame: Pre operatively]
  • Changes in beta angle [Time frame: 2 months post-operatively, 6 months post-operatively, 12 months post-operatively, 24-36-48-60-72-84-96-108-120 months post-operatively]
  • Changes in alpha angle [Time frame: 2 months post-operatively, 6 months post-operatively, 12 months post-operatively, 24-36-48-60-72-84-96-108-120 months post-operatively]
  • Medial distal tibial angle [Time frame: Pre operatively]
Secondary outcome measures (1)
  • Changes in visual analogue scale [Time frame: Pre operatively, 2 months post-operatively, 6 months post-operatively, 12 months post-operatively, 24-36-48-60-72-84-96-108-120 months post-operatively]

Eligibility criteria

Inclusion criteria

  • Males and females
  • age ≥ 18 years at the time of surgery
  • patients who underwent ankle replacement surgery from January 2011 to March 2026

Exclusion criteria

\- age < 18 years at the time of surgery

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-control

Study locations

Italy · 1 center
  • Irccs Istituto Ortopedico Galeazzi — Milan

Identifiers

NCT: NCT03650010 · Tarus

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗