From Brain Currents to Interpersonal Flow: Investigating the Social Processing Stream of Schizophrenia
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: This is not an intervention study.
- Who it may be relevant to
- Registry conditions: Schizophrenia, Cognitive Impairment, Social Competence. Basic parameters: 17 years — 55 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The overall objective of this project is to identify the neural signature of the impaired ability to relate socially seen in individuals with schizophrenia. A hypothesized path from the neural processes of social cognition, to social cognition assessed behaviorally, to real-life social interactions is examined. Secondary aims are to compare electrophysiological measures of high vs low level social cognition; to develop assessment methods of real-life behavior; and to increase the ecological validity of schizophrenia research. Much research within the field is devoid of personal meaning and interpersonal context. This project's use of personalized assessment allows for an ecologically valid approach to the social deficits of schizophrenia.
Interventions
- Other This is not an intervention study
This is not an intervention study
Primary outcome measures
- Neurophysiology: EEG [Time frame: 1 day (when assessed)]
- Neurophysiology: ERP [Time frame: 1 day (when assessed)]
- Cognition [Time frame: 1 day (when assessed)]
- Negative symptoms: clinician-rated [Time frame: 1 day (when assessed)]
- Negative symptoms: objective 1 [Time frame: 1 day (when assessed)]
- Negative symptoms: objective 2 [Time frame: 1 day (when assessed)]
- Social cognition: complex ToM [Time frame: 1 day (when assessed)]
- Social cognition: low level ToM [Time frame: 1 day (when assessed)]
- Social cognition: facial emotion perception [Time frame: 1 day (when assessed)]
- Social cognition: body language reading [Time frame: 1 day (when assessed)]
Eligibility criteria
Inclusion criteria
- schizophrenia
- schizoaffective disorder
Exclusion criteria
- diabetes
- Hyperthyroidism
- severe head trauma
- neurological disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT03543553 · ecoval