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Enrolling by invitation NCT03492372

Molecular Characterization of Spinal Tissue

— Observational Spinal Diseases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Waste tissues are collected at the time of spinal surgery..
Who it may be relevant to
Registry conditions: Spinal Diseases. Basic parameters: 1 year — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The researchers are trying to identify molecular mechanisms that control spine deformity and degenerative changes that can be used for therapeutic strategies.

Detailed description

Discarded surgical material from spinal procedures is collected. RNA analysis and other tests on the tissue is performed to determine markers of pathologic disease and to develop pharmacologic treatment strategies for pediatric spinal disorders.

Interventions

  • Other Waste tissues are collected at the time of spinal surgery.
    This is a single visit study. Waste tissues are collected at the time of spinal surgery.

Primary outcome measures

  • RNA expression [Time frame: Baseline]

Eligibility criteria

Inclusion criteria

  • Children and adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure. Material from adults may be collected as a control group.

Exclusion criteria

  • Surgeries where spinal tissues are not being removed.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

United States · 1 center
  • Mayo Clinic — Rochester

Identifiers

NCT: NCT03492372 · 14-008177

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗