The Genetics of Pulmonary Fibrosis
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Blood draw, Questionnaire.
- Who it may be relevant to
- Registry conditions: Idiopathic Pulmonary Fibrosis (IPF). Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Idiopathic Pulmonary Fibrosis, a Disease Initiated by Mucociliary Dysfunction
Overview
This study seeks to screen first degree family members of people with Idiopathic Pulmonary Fibrosis (IPF) for the earliest signs of lung fibrosis.
Detailed description
The purpose of this study is to explore genetic factors associated with the development of pulmonary fibrosis. The investigators aim is to identify and explore genetic loci that affect development of pulmonary fibrosis and also explore related environmental exposures. Idiopathic pulmonary fibrosis (IPF) is one of the interstitial lung diseases under the broader umbrella of idiopathic interstitial pneumonias (IIP). The investigators hypothesize that inherited genetic factors are associated with pulmonary fibrosis. To investigate the genetics of pulmonary fibrosis, the investigators plan to enroll individuals with pulmonary fibrosis and their family members.
Interventions
- Other Blood draw
Blood draw - Other Questionnaire
Pulmonary Fibrosis Questionnaire
Primary outcome measures
- Identify and explore genetic loci and related environmental exposures in individuals with familial pulmonary fibrosis and their relatives. [Time frame: Baseline]
Eligibility criteria
Inclusion criteria
- Age at least 18 years old
- Family member diagnosed with IPF
Exclusion criteria
\- No family member with IPF
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Family-based
Study locations
United States · 1 center
- University of Colorado Anschutz Medical Campus — Aurora
Identifiers
NCT: NCT03478553 · 15-1147 · W81XWH-17-1-0597_1a