Pediatric PET/MR Image Registry
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: PET/MR imaging, MR imaging, PET/CT imaging.
- Who it may be relevant to
- Registry conditions: Soft Tissue, Lymphoma, Osteosarcoma. Basic parameters: up to 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The purpose of this study is to compare whole body magnetic resonance (MR) imaging, whole body positron emission tomography (PET)/MR imaging, and (if available) PET/Computed Tomography (CT) imaging for the diagnosis of tumors in children and young adults. Sensitivities, specificities and diagnostic accuracies of the different imaging modalities will be compared for significant differences.
Interventions
- Diagnostic test PET/MR imaging
undergo PET/MR imaging - Diagnostic test MR imaging
Undergo MR imaging - Diagnostic test PET/CT imaging
Undergo PET/CT imaging
Primary outcome measures
- Number of tumors [Time frame: up to 12 months]
Secondary outcome measures (1)
- Metabolic activity of tumors [Time frame: up to 12 months]
Eligibility criteria
Inclusion criteria
- Patients with proven solid tumors or newly diagnosed mass strongly suspected to represent a solid tumor.
- We might also include some patients with leukemia if there is concern for a focal lesion in any of their organs.
- Participant's parents (if participant is under 18) or the participant (if participant is 18 years or older) must willingly give written informed consent prior to any image transfer to the image registry.
Exclusion criteria
- Patient has contraindications for MRI or PET/MR. This includes patients with cardiac pacemakers or intracranial vascular clips as well as patients with a blood glucose level > 200 mg/dl.
- Lack of parental permission (if participant is younger than 18) or lack of informed consent (if participant is at least 18 years of age).
- Patient has a CNS primary tumor.
- Pregnant women and fetuses
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Stanford University, School of Medicine — Palo Alto
Identifiers
NCT: NCT03458520 · IRB-44706 · PEDSVAR0049 · 5U24CA264298-04