International Bifurcation Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: PCI of bifurcation lesions.
- Who it may be relevant to
- Registry conditions: Coronary Bifurcation Lesion. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Russia
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
International Prospective Register on Treatment of Coronary Artery Bifurcation Lesions
Overview
The IBS registry is an observational, multi-center, real-world registry of stenting in coronary bifurcation lesions that will collect information on procedures and outcomes from various participating centers. The aim of this registry is to investigate long-term clinical results and predictors of adverse outcomes after PCI for coronary bifurcation lesions among various participating centers.
Detailed description
Patients with coronary bifurcation lesions, if they meets all the study inclusion criteria and none of the exclusion criteria, after signing the informed consent, they will underwent PCI according to the current standard of care and will be entered in the registry. Follow-up for all subjects will continue for 5 years.
Interventions
- Procedure PCI of bifurcation lesions
Different approaches for treatment of bifurcation coronary artery disease.
Primary outcome measures
- Procedural success [Time frame: 1 day]
Secondary outcome measures (6)
- Major Adverse Cardiac and Cerebrovascular Events [Time frame: 6 months, 1 year, 3 years, 5 years]
- All cause mortality [Time frame: 6 months, 1 year, 3 years, 5 years]
- Death from cardiac causes [Time frame: 6 months, 1 year, 3 years, 5 years]
- Myocardial infarction [Time frame: 6 months, 1 year, 3 years, 5 years]
- Target vessel revascularization [Time frame: 6 months, 1 year, 3 years, 5 years]
- Stent thrombosis [Time frame: 6 months, 1 year, 3 years, 5 years]
Eligibility criteria
Inclusion criteria
- Age ≥ 18 years
- Any type of bifurcation lesion in major epicardial artery
Exclusion criteria
- Patient refused informed consent to participate in the registry
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Russia · 1 center
- Meshalkin National Research Center — Novosibirsk
Publications
- Khelimskii D, Bessonov I, Sapozhnikov S, Badoyan A, Baranov A, Mamurjon M, Manukian S, Utegenov R, Krestyaninov O. Impact of Prolonged Dual Antiplatelet Therapy After Bifurcation Percutaneous Coronary Intervention in Patients with High Ischemic Risk. Am J Cardiovasc Drugs. 2024 Jul;24(4):577-588. doi: 10.1007/s40256-024-00657-1. Epub 2024 Jun 13. PMID 38871947
Identifiers
NCT: NCT03450577 · IBS