Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Lung Recruitment Maneuver, Fluid Administration.
- Who it may be relevant to
- Registry conditions: Anesthesia, Intravenous Fluid, Blood Pressure. Basic parameters: up to 17 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.
Detailed description
In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration.
It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.
Interventions
- Other Lung Recruitment Maneuver
Lung Recruitment Maneuver by Anesthesiologist - Other Fluid Administration
Administration of IV Fluid by Anesthesiologist
Primary outcome measures
- Change in stroke volume [Time frame: immediately before and after each intervention]
Secondary outcome measures (3)
- Change in arterial compliance effect on Systolic Pressure Variation (mmHg) [Time frame: immediately before and after each intervention]
- Change in arterial compliance effect on Pulse Pressure Variation (%) [Time frame: immediately before and after each intervention]
- Change in arterial compliance effect on Plethysmographic Variability Index (%) [Time frame: immediately before and after each intervention]
Eligibility criteria
Inclusion criteria
- 0 to < 18 years old
- Undergoing surgery at Boston Children's Hospital under general anesthesia
- mechanically ventilated with an endotracheal tube
- Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure
Exclusion criteria
- Prematurity
- Low birth weight
- Congenital heart disease
- Left or right ventricular dysfunction
- Cardiac arrhythmia
- Pulmonary hypertension
- Preoperative parenchymal or interstitial lung disease
- Intracranial hypertension
- Poor transthoracic acoustic window
- Obesity
- Allergy to ultrasound transmission gel
- Need for single lung ventilation
- Systemic hypertension on antihypertensive medications
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- Boston Children's Hospital — Boston
Identifiers
NCT: NCT03431064 · IRB-P00025702