Submandibular Gland Preservation in Neck Dissection
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: modified neck dissection, traditional neck dissection.
- Who it may be relevant to
- Registry conditions: Neck Dislocation, Oral Cancer. Basic parameters: up to 90 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Submandibular Gland Preservation During Neck Dissection for Oral Squamous Cell Carcinoma
Overview
Trial design: a randomized controlled trial. Eligibility criteria for participants: patients with primary early stage oral squamous cell carcinoma. Exclusion criteria: cancer of the floor of the mouth. Interventions: submandibular gland is preserved during neck dissection for patients of the experimental group; submandibular gland is removed during neck dissection for patients of the control group. Primary Parameters: survival rate, mortality rate
Interventions
- Procedure modified neck dissection
Modified neck dissection with preservation of submandibular gland. The submandibular gland is preserved during neck dissection. - Procedure traditional neck dissection
traditional neck dissection without preservation of submandibular gland
Primary outcome measures
- 5-year survival rate [Time frame: 5-year after operation]
- 3-year survival rate [Time frame: 3-year after operation]
- 5-year regional recurrence rate [Time frame: 5-year after operation]
- 3-year regional recurrence rate [Time frame: 3-year after operation]
- 1-year regional recurrence rate [Time frame: 1-year after operation]
Eligibility criteria
Inclusion criteria
Primary oral squamous cell carcinoma of early stage (T1N0 and T2N0).
Exclusion criteria
Cancer of the floor of the mouth.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Peking University School of Stomatology — Beijing
Identifiers
NCT: NCT03385720 · sujiazeng