CArdioSurgEry Atrial Fibrillation Register
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Atrial Fibrillation. Basic parameters: 18 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Germany
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
CArdioSurgEry Atrial Fibrillation Register - CASE-AF Register
Overview
CASE AF aims to describe the reality of medical care of patients in whom atrial fibrillation is treated by cardiac surgical ablation.
Detailed description
CASE AF aims to describe the reality of medical care of patients in whom atrial fibrillation is treated by cardiac surgical ablation. In particular, the following questions should be answered:
* Indication: Which are the different indications for cardiac surgical ablation in patients with atrial fibrillation? * How often and in which patients the different concepts of surgery and ablation procedures are used? At the same time, how often an intervention at the left atrial appendage is carried out? * Safety: How secure is the cardiac surgical ablation of atrial fibrillation (periprocedural, during hospital stay and during the long-term follow up)? * Effectiveness: How effectively is the cardiac surgical ablation of atrial fibrillation (procedural success)? How often are AF recurrences in the long-term follow up? * What is the concommitant medical treatment after surgical ablation?
Primary outcome measures
- Number of major bleeding events [Time frame: 12 months]
Secondary outcome measures (2)
- Number of major adverse cardiac events [Time frame: 12 months]
- Complications during hospital stay [Time frame: 12 months]
Eligibility criteria
Inclusion criteria
- Atrial fibrilation
- Treated by cardiac surgical ablation
Exclusion criteria
- Patient denies participation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Germany · 3 centers
- Klinikum Bogenhausen — München
- Asklepios Harburg — Hamburg
- Schüchtermann Kliniken — Bad Rothenfelde
Publications
- Niemann B, Doll N, Grubitzsch H, Hanke T, Knaut M, Senges J, Ouarrak T, Vondran M, Boning A. Surgical Ablation of Atrial Fibrillation in High-Risk Patients: Success versus Risk. Thorac Cardiovasc Surg. 2025 Aug;73(5):373-386. doi: 10.1055/a-2334-9039. Epub 2024 May 28. PMID 38806162
Identifiers
NCT: NCT03091452 · CASE-AF