Shanghai Pediatric Cataract Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: intraocular lens implantation.
- Who it may be relevant to
- Registry conditions: Pediatric Cataract, Congenital Cataract, Traumatic Cataract, Visual Outcome. Basic parameters: 2 months — 20 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Visual Outcome Evaluation and Genetic Analysis: Shanghai Pediatric Cataract Study
Overview
The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of pediatric cataract participants, including congenital and traumatic cataract. The investigators will further investigate into the various genetic and environmental factors that may contribute to the pathogenesis of pediatric cataract.
Interventions
- Procedure intraocular lens implantation
1）Pediatric cataract patients with intraocular lens implantation and those without intraocular lens implantation；2）Traumatic cataract patients with intraocular lens implantation and those without intraocular lens implantation
Primary outcome measures
- Differences in the visual outcomes of pediatric cataract patients. [Time frame: Follow-up until ten years after surgery.]
- Genetic diversity based on biospecimen samples of pediatric cataract patients. [Time frame: Analyzed within six months after surgery.]
Secondary outcome measures (1)
- Differences in the clinical phenotypes of pediatric cataract patients. [Time frame: Evaluated before receiving the cataract surgery.]
Eligibility criteria
Inclusion criteria
- Clinical diagnosis of pediatric cataract
- Must be able to cooperate with the ophthalmic examination
Exclusion criteria
- Clinical diagnosis of mental illness
- Mentally disabled
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
China · 1 center
- Eye and ENT Hospital of Fudan University — Shanghai
Publications
- Zhu X, He W, Du Y, Kraus CL, Xu Q, Sun T, Yu J, Lu Y. Presence of Posterior Staphyloma in Congenital Cataract Children. Curr Eye Res. 2019 Dec;44(12):1319-1324. doi: 10.1080/02713683.2019.1637437. Epub 2019 Jul 5. PMID 31246115
Identifiers
NCT: NCT03063216 · SH-PCS