China Collaborative Study on Epidemiology of Acute Kidney Injury
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: no intervention.
- Who it may be relevant to
- Registry conditions: Acute Kidney Injury. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Acute kidney injury (AKI) is a common clinical syndrome, especially patients in the hospital. AKI has become a huge medical burden in China. Little information is available about this disease burden in our country. The investigators aimed to evaluate the burden of AKI and to analyze the related risk factors.
Detailed description
The investigators launch a nationwide of all patients, who were admitted to hospital from 2011-2016. Patients were diagnosed on the basis of changes in serum creatinine by the laboratory information system. The investigators assessed rates of AKI according to the criteria of 2012 Kidney Disease Improving Global Outcomes (KDIGO).
Interventions
- Other no intervention
Primary outcome measures
- Incidence of AKI [Time frame: Jan. 2011 to Oct. 2016]
Secondary outcome measures (5)
- Recognition rate of AKI [Time frame: Jan. 2011 to Oct. 2016]
- Proportion of nephrology referral [Time frame: Jan. 2011 to Oct. 2016]
- In-hospital mortality [Time frame: Jan. 2011 to Oct. 2016]
- Longer ICU stay [Time frame: Jan. 2011 to Oct. 2016]
- Higher medical cost [Time frame: Jan. 2011 to Oct. 2016]
Eligibility criteria
Inclusion criteria
- The patients diagnosed on the basis of changes in serum creatinine according to the criteria of 2012 Kidney Disease Improving Global Outcomes(KDIGO)
Exclusion criteria
- Serum creatinine record less than two times during hospitalization
- Patients being diagnosed with End-stage kidney disease (chronic kidney disease stage 5)
- Nephrectomy
- Kidney transplantation
- Peak serum creatinine of less than 53µ mol/L
- Serum creatinine decrease after amputation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
China · 1 center
- Nephrology Dept,Guangdong General Hospital — Guangzhou
Publications
- Xu L, Wu Y, Chen Y, Li R, Wang Z, Li Z, Liu G, Yu L, Shi W, Liang X; China collaborative study on AKI (CCS-AKI). Is acute kidney injury age-dependent in older adults: an observational study in two centers from North China. BMC Geriatr. 2021 Jan 6;21(1):7. doi: 10.1186/s12877-020-01906-z. PMID 33407184
Identifiers
NCT: NCT03054142 · CCS-AKI RF2011-2016