Ion Therapy Patient Registry
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Protons and Carbon Ions.
- Who it may be relevant to
- Registry conditions: Ion Beam Radiation Therapy for Tumor Patients. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Austria
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
A Prospective Registry Study to Record Clinical Results and Side Effects of Ion Beam Therapy at MedAustron
Overview
The purpose of the study is the prospective and standardized data collection of patients treated with ion therapy at MedAustron.
Detailed description
During and up to 10 years after radiation therapy data regarding tumor control and treatment response as well as acute and late toxicities will be collected at regular time intervals. Additionally quality of life and sociodemographic status will be assessed in all study patients and neurocognitive assessment will be performed in patients undergoing ion radiation of the brain.
Interventions
- Radiation Protons and Carbon Ions
Primary outcome measures
- Therapy response [Time frame: 10 years]
- Overall survival [Time frame: 10 years]
- Progression-free survival [Time frame: 10 years]
- Local progression-free survival [Time frame: 10 years]
- Cause-specific survival [Time frame: 10 years]
- Toxicity according to NCI CTCAE [Time frame: 10 years]
Secondary outcome measures (4)
- EORTC-QLQ-C30 [Time frame: Through study completion, at 3, 5, and 10 years]
- EORTC-QLQ-BN20 [Time frame: Through study completion, at 3, 5, and 10 years]
- EORTC-QLQ-PR25 [Time frame: Through study completion, at 3, 5, and 10 years]
- Neurocognitive test battery [Time frame: Through study completion, at 3, 5, and 10 years]
Eligibility criteria
Inclusion criteria
- Patients with tumor disease treated with ion beam therapy at MedAustron
- Signed informed consent form
Exclusion criteria
- Comorbidities endangering treatment delivery or study compliance
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Austria · 1 center
- EBG MedAustron GmbH — Wiener Neustadt
Identifiers
NCT: NCT03049072 · REGI-MA-002015