Acceptance of Uterus Transplantation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Uterus transplantation.
- Who it may be relevant to
- Registry conditions: Resolve Infertility. Basic parameters: 20 years — 40 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Transplantation of an Uterus for Treatment of an Absolute Uterine Infertility
Overview
Transplantation of an uterus
Detailed description
Uterus transplantation will be performed from live donors to patients with absolute uterine factor infertility. Organ procurement from the donor will be performed by laparotomy. Transplantation will also be performed by laparotomy. Embryo transfer will be done 10-12 months after transplantation. After birth of 1-3 children the uterus will be removed by hysterectomy.
Interventions
- Procedure Uterus transplantation
Primary outcome measures
- Number of patients who are interested in an uterus transplantation [Time frame: 3 years]
- Number of patients from these who do have a potential donor [Time frame: 3 years]
- Number of patients from these who do have a medical indication for an uterus transplantation [Time frame: 3 years]
Eligibility criteria
Inclusion criteria
- age below 40 years
- absolute uterine factor infertility
- BMI < 30
Exclusion criteria
- systemic disease
- psychiatric disease
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Other
Study locations
Center list to be confirmed — check the primary protocol.
Publications
- Brucker SY, Brannstrom M, Taran FA, Nadalin S, Konigsrainer A, Rall K, Scholler D, Henes M, Bosmuller H, Fend F, Nikolaou K, Notohamiprodjo M, Rosenberger P, Grasshoff C, Heim E, Kramer B, Reisenauer C, Hoopmann M, Kagan KO, Dahm-Kahler P, Kvarnstrom N, Wallwiener D. Selecting living donors for uterus transplantation: lessons learned from two transplantations resulting in menstrual functionality a PMID 29270725
Identifiers
NCT: NCT03048396 · FEH_Uterustransplantation