Molecular and Genetic Analysis of Lung Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Lung Cancer. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Investigators use a genome-wide approach within a case-control design to identify SNPs that show evidence of association with lung cancer risk and survival.
Detailed description
Investigators also investigate how genetic variants may affect cancer treatment, at various stages of disease development, in order to determine prognostic and predictive factors for survival.
Primary outcome measures
- Survival among patients at different stages of lung cancer and treatment will be measured using questionnaires along with medical chart data to monitor treatment and disease progression [Time frame: 20 years]
Secondary outcome measures (3)
- Overall survival [Time frame: 20 years]
- Progression-free survival [Time frame: 20 years]
- Treatment toxicities [Time frame: 20 years]
Eligibility criteria
Inclusion criteria
- healthy controls: participants without evidence of any cancer
- cases: pathology proven primary lung cancer
Exclusion criteria
- younger than 18 years old
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-only
Study locations
United States · 1 center
- Massachusetts General Hospital — Boston
Identifiers
NCT: NCT03029325 · 1999P-004935 · 5P30CA006516-50