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Recruiting NCT03019471

Non Invasive Cancer Test (NICT): a Proof of Principle Study.

— Observational Neoplasmata

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Isolation of tumor DNA.
Who it may be relevant to
Registry conditions: Neoplasmata. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Netherlands
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The investigators aim to collect tumor DNA out of blood of cancer patients. If this is successful this could lead to the development of a cancer test in blood in the future, which is less invasive than current diagnostic methods.

Interventions

  • Genetic Isolation of tumor DNA

Primary outcome measures

  • ctDNA [Time frame: One year]

Eligibility criteria

Inclusion criteria

  • Patients with newly diagnosed local or metastatic breast cancer, colorectal cancer, non-small cell lung cancer and anaplastic glioblastoma, before start of radiation therapy, chemoradiation or chemotherapy.
  • Patients age > 18 years, willing and able to comply with the protocol as judged by the investigator with a signed informed consent

Exclusion criteria

  • Patients with a history of malignant disease other than the disease under study, with an exception for adequately treated squamous cell carcinoma of the skin, basal cell carcinoma of the skin and in situ cervix carcinoma.
  • Pregnancy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Netherlands · 1 center
  • Maastricht University Medical Center — Maastricht

Identifiers

NCT: NCT03019471 · NL55080.068.15

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗