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Recruiting NCT03017118

Turmeric for Patients With Basal Joint Arthritis

No phase Interventional Thumb Osteoarthritis

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Turmeric, Placebo.
Who it may be relevant to
Registry conditions: Thumb Osteoarthritis. Basic parameters: from 40 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

A Randomized Controlled Trial Using Turmeric for Patients With Basal Joint Arthritis

Overview

The aim of this study is to assess whether the use of a commercially available nutraceutical, turmeric, is an effective option to manage pain and stiffness in patients with basal joint arthritis. To conduct a pilot Randomized Controlled Trial evaluating the impact of turmeric on basal joint arthritis.

Interventions

  • Dietary supplement Turmeric
    Subjects will receive turmeric (100 mg pastille) 3 times per day for 6 weeks.
  • Other Placebo
    Subjects in the control group will receive a placebo 3 times per day for 6 weeks.

Primary outcome measures

  • Change in baseline pain intensity [Time frame: Enrollment, 6 weeks, and 3 months]
  • Change in baseline disability [Time frame: Enrollment, 6 weeks, and 3 months]

Eligibility criteria

Inclusion criteria

  • 40 years of age or older
  • English fluency and literacy
  • Seeking care for basal joint pain
  • Tender over basal joint
  • Positive distraction rotation test (rotation of the thumb metacarpal base while applying axial traction)
  • Radiographic evidence of Eaton stage 1 and 2 only

Exclusion criteria

  • Secondary gains (litigations or worker compensation) procedures that may interfere with patients' motivation for treatment
  • Inability or unwillingness to participate in a trial study
  • Rheumatoid Arthritis or other inflammatory disorder diagnoses
  • Post-traumatic osteoarthritis
  • Patients on Coumadin/Steroids/NSAIDs/Tylenol
  • Diabetes Mellitus
  • Pregnant or lactating women
  • Basal joint arthritis of Eaton stage 3
  • Patients seeking other treatment for their basal joint arthritis (splint, corticosteroid injection, surgery)

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

United States · 1 center
  • Massachusetts General Hospital — Boston

Identifiers

NCT: NCT03017118 · 2016P001402

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗