Intra- and Inter-fraction Changes in Radiation Therapy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Radiation Therapy.
- Who it may be relevant to
- Registry conditions: Cancer. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Analysis to quantify intra-fraction, inter-fraction and post-treatment changes in tumor target volumes and surrounding normal organs in radiation therapy.
Detailed description
The accurate and detailed knowledge of the changes (e.g., anatomically/biologically intra- and inter-fraction changes) to be obtained from this study would allow the research team to determine how Adaptive Radiation Therapy (ART) should be performed for a given tumor site/type. Radiation oncologists then can choose a proper ART strategy for a given tumor type to account for the anatomic/biological intra- and inter-fraction changes, improving accuracy of radiation therapy delivery, and in turn reducing treatment related toxicities and/or improving tumor local control.
Interventions
- Radiation Radiation Therapy
Radiation therapy plans for cancer patients who have completed treatment.
Primary outcome measures
- Changes of volumes from baseline of organs at risk during and after radiation therapy. [Time frame: 2 years]
Secondary outcome measures (1)
- Changes of volumes from baseline or tumors during and after radiation therapy. [Time frame: 2 years]
Eligibility criteria
Inclusion criteria
°Completed radiation therapy
Exclusion criteria
°Subjects who refuse voluntary participation
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Case-control
Study locations
United States · 1 center
- Froedtert Hospital — Milwaukee
Identifiers
NCT: NCT02344121 · 22316