Predictive Factors and Autonomy Level Change
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6.
- Who it may be relevant to
- Registry conditions: Memory Impairment. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Predictive Factors of the Autonomy Level Change Related to Memory Disorders
Overview
The Alzheimer's disease or related disorders (ADRD) are among the most disabling diseases because of their main features such as cognitive impairment, loss of functional autonomy and behavioural disorders. In absence of current curative treatment, the identification of the predictive risk factors of progression of the disease, evaluated through its main symptoms, represents a major stake of public health. The investigators aimed at developing a database, which includes the patient medical records on a prospective basis, in collaboration with the medical and administrative personal and with the University hospital computer science department. The main objective is to study the predictive factors associated with the change of functional autonomy level, measured every 6 months to 12 months by phone, in a Memory Clinic. The study population would consist in about 1000 patients with ADRD. The length of follow-up of each patient will be 3 years.
Interventions
- Other The Lawton Instrumental Activities of Daily Living score (IADL), and the disability assessment of dementia score (DAD-6
Primary outcome measures
- Functional autonomy level [Time frame: 3 years]
Secondary outcome measures (1)
- Cognitive function level [Time frame: 3 years]
Eligibility criteria
Inclusion criteria
- Patients who undergo a medical visit in the Memory Clinic for the 1st time
- Patients living at home or in housing
- Patients with memory impairment, at all stage of the disease
Exclusion criteria
- Patients in institution
- Patients under legal protection
- Patients with a hearing or visual impairment, which dot not allow to carry out the examination
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- N/A
- Model
- Single group
- Masking
- Open label
- Primary purpose
- Health services research
Study locations
France · 2 centers
- Hôpital Dugoujon — Caluire-et-Cuire
- Hospices Civils de Lyon - Hôpital des Charpennes — Lyon
Publications
- Dauphinot V, Moutet C, Rouch I, Verdurand M, Mouchoux C, Delphin-Combe F, Gaujard S, Krolak-Salmon P; MEMORA group. A multicenter cohort study to investigate the factors associated with functional autonomy change in patients with cognitive complaint or neurocognitive disorders: the MEMORA study protocol. BMC Geriatr. 2019 Jul 18;19(1):191. doi: 10.1186/s12877-019-1204-1. PMID 31319809
Identifiers
NCT: NCT02302482 · 2014.868