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Recruiting NCT02211365

Registro Campania Salute Network on Hypertension

— Observational Hypertension; Heart Disease, Hypertensive

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Hypertension; Heart Disease, Hypertensive. Basic parameters: 18 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Registro Campania Salute Network for the Treatment of Hypertension and Correlated Diseases

Overview

The Registro Campania Salute Network (RCSN) is a prospective registry aimed at improving the management of essential hypertension by integrating the activity of general practitioners (GPs) with that of the hypertension specialist. It involves selected GPs homogeneously allocated in the regional area, and the Hypertension Clinic of the Federico II University in Naples, which served as co-ordinating centre. Through the RCSN system it is possible to store clinical data detected at each visit between the peripheral units and the co-ordinating centre and to support scientific analysis of the dataset.

Detailed description

The patients will be followed over a period of twenty years and all clinical data will be recorded in order to investigate the role of hypertension and correlated disease on this patient population

Primary outcome measures

  • MACCE [Time frame: every year up to 20 years]

Eligibility criteria

Inclusion criteria

-Hypertension

  • 18 years old

Exclusion criteria

  • Refused to sign informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • Department od advanced biomedical sciences, Università degli studi di Napoli Federico II, — Naples

Publications

  • Mancusi C, Basile C, Gerdts E, Fucile I, Manzi MV, Lembo M, Pacella D, Giugliano G, Canciello G, Piccolo R, Spinelli A, Morisco C, De Luca N, Trimarco B, de Simone G, Bossone E, Izzo R, Losi MA, Esposito G. Carotid plaque offsets sex-related differences in cardiovascular risk of young hypertensive patients. Eur J Intern Med. 2024 Dec;130:137-143. doi: 10.1016/j.ejim.2024.09.007. Epub 2024 Sep 17. PMID 39294033
  • Trimarco V, Manzi MV, Izzo R, Mone P, Lembo M, Pacella D, Esposito G, Falco A, Morisco C, Gallo P, Santulli G, Trimarco B. The therapeutic concordance approach reduces adverse drug reactions in patients with resistant hypertension. Front Cardiovasc Med. 2023 May 5;10:1137706. doi: 10.3389/fcvm.2023.1137706. eCollection 2023. PMID 37215551
  • Lembo M, Acampa W, Rao MAE, Manzi MV, Morisco C, Esposito G, Assante R, Zampella E, Nappi C, Gaudieri V, Mannarino T, Mancusi C, de Simone G, Izzo R, Cuocolo A, Trimarco B. Left Ventricular Mechano-Energetic Efficiency Identifies an Early Impairment of Myocardial Blood Flow in Arterial Hypertension. Hypertension. 2023 Jul;80(7):1534-1543. doi: 10.1161/HYPERTENSIONAHA.123.21071. Epub 2023 May 12. PMID 37170833
  • Stabile E, Franzese M, Chianese S, Alfani A, Gerardi D, Colaiori I, Annunziata M, Nappi P, Scalise M, Di Serafino L, Puzone B, Avvedimento M, Leone A, Ilardi F, Piccolo R, Franzone A, Cirillo P, Morisco C, Trimarco B, Esposito G. Predictors of adherence to composite therapy after acute coronary syndromes. J Cardiovasc Med (Hagerstown). 2021 Aug 1;22(8):645-651. doi: 10.2459/JCM.0000000000001201. PMID 33966020
  • Mancusi C, Losi MA, Albano G, De Stefano G, Morisco C, Barbato E, Trimarco B, De Luca N, de Simone G, Izzo R. Characteristics and Outcomes of Patients Presenting With Hypertensive Urgency in the Office Setting: The Campania Salute Network. Am J Hypertens. 2020 Apr 29;33(5):414-421. doi: 10.1093/ajh/hpaa003. PMID 31930302
  • Canciello G, Mancusi C, Losi MA, Izzo R, Trimarco B, de Simone G, De Luca N. Aortic Root Dilatation Is Associated With Incident Cardiovascular Events in a Population of Treated Hypertensive Patients: The Campania Salute Network. Am J Hypertens. 2018 Nov 13;31(12):1317-1323. doi: 10.1093/ajh/hpy113. PMID 30099532
  • Mancusi C, Izzo R, Ferrara LA, Rozza F, Losi MA, Canciello G, Pepe M, de Luca N, Trimarco B, de Simone G. Is increased uric acid a risk factor or a defensive response? The Campania Salute Network. Nutr Metab Cardiovasc Dis. 2018 Aug;28(8):839-846. doi: 10.1016/j.numecd.2018.04.013. Epub 2018 May 4. PMID 29898822
  • Izzo R, Losi MA, Stabile E, Lonnebakken MT, Canciello G, Esposito G, Barbato E, De Luca N, Trimarco B, de Simone G. Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network. Hypertension. 2017 Jan;69(1):136-142. doi: 10.1161/HYPERTENSIONAHA.116.08158. Epub 2016 Nov 28. PMID 27895192

Identifiers

NCT: NCT02211365 · 16/14

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗