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Recruiting NCT02182921

Evaluation of Cataract Surgery Outcome

— Observational Cataract High Myopia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Cataract, High Myopia. Basic parameters: up to 90 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Evaluation of Surgical Outcomes of Cataract Surgery

Overview

The purpose of this study is to evaluate the visual outcome of the cataract surgery, including best uncorrected and corrected visual acuity, spherical equivalent, wavefront aberration and other measurements.

Primary outcome measures

  • Change from baseline in visual acuity at one month after cataract surgery [Time frame: Follow-up until one month after surgery]
  • Change from baseline in spherical equivalent at one month after cataract surgery [Time frame: Follow-up until one month after surgery]
  • Change from baseline in visual acuity at six months after cataract surgery [Time frame: Follow-up until six months after surgery]
  • Change from baseline in spherical equivalent at six months after cataract surgery [Time frame: Follow-up until six months after cataract surgery]
Secondary outcome measures (6)
  • Change from baseline in wavefront aberration at one month after cataract surgery [Time frame: Follow-up until one month after surgery]
  • Change from baseline in contrast sensitivity at one month after cataract surgery [Time frame: Follow-up until one month after surgery]
  • Change from baseline in intraocular light scattering at one month after cataract surgery [Time frame: Follow-up until one month after surgery]
  • Change from baseline in wavefront aberration at six months after cataract surgery [Time frame: Follow-up until six months after surgery]
  • Change from baseline in contrast sensitivity at six months after cataract surgery [Time frame: Follow-up until six months after surgery]
  • Change from baseline in intraocular light scattering at six months after cataract surgery [Time frame: Follow-up until six months after surgery]

Eligibility criteria

Inclusion criteria

  • Clinical diagnosis of cataract
  • Must be able to cooperate with the ophthalmic examination

Exclusion criteria

  • Clinical diagnosis of mental illness
  • Mentally disabled

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-control

Study locations

China · 1 center
  • Eye and ENT Hospital of Fudan University — Shanghai

Publications

  • Zhou J, Chen Y, Meng J, Cheng K, Qi J, Du Y, Yao Y, Lu Y, He W, Zhu X. Comparative analysis of iris blood flow after first-eye and second-eye cataract surgeries: insights into increased pain perception in the second eye. BMJ Open Ophthalmol. 2025 Aug 19;10(1):e002162. doi: 10.1136/bmjophth-2025-002162. PMID 40835236
  • Chen C, Zhou J, Cheng K, Hu X, Zhu M, Du Y, Meng J, Lu Y, He W, Zhu X. Lens position change following cataract surgery in eyes with thick lenses: an SS-OCT based study. Br J Ophthalmol. 2025 Sep 23;109(10):1120-1125. doi: 10.1136/bjo-2025-327414. PMID 40461064
  • Yao Y, Meng J, He W, Zhang K, Wei L, Cheng K, Lu Y, Zhu X. Associations between anterior segment parameters and rotational stability of a plate-haptic toric intraocular lens. J Cataract Refract Surg. 2021 Nov 1;47(11):1436-1440. doi: 10.1097/j.jcrs.0000000000000653. PMID 34675151
  • Lu Q, Wei L, He W, Zhang K, Wang J, Zhang Y, Rong X, Zhao Z, Cai L, He X, Wu J, Ding D, Lu Y, Zhu X. Lens Opacities Classification System III-based artificial intelligence program for automatic cataract grading. J Cataract Refract Surg. 2022 May 1;48(5):528-534. doi: 10.1097/j.jcrs.0000000000000790. PMID 34433780
  • Zhu X, Lu Q, Yao Y, Xu X, Lu Y. Intraoperative Pain Sensation During Cataract Surgery: Why Does Timing Matter? Curr Eye Res. 2021 Jul;46(7):971-977. doi: 10.1080/02713683.2020.1857776. Epub 2020 Dec 15. PMID 33249933
  • Lu Q, He W, Lu Y, Zhu X. Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos. Eye Vis (Lond). 2020 Sep 9;7:47. doi: 10.1186/s40662-020-00212-4. eCollection 2020. PMID 32974413
  • Zhu X, Qi J, He W, Zhang S, Zhang K, Lu Q, Lu Y. Early transient intraocular pressure spike after cataract surgery in highly myopic cataract eyes and associated risk factors. Br J Ophthalmol. 2020 Aug;104(8):1137-1141. doi: 10.1136/bjophthalmol-2019-315117. Epub 2019 Nov 8. PMID 31704699
  • Zhu X, He W, Zhang K, Lu Y. Factors influencing 1-year rotational stability of AcrySof Toric intraocular lenses. Br J Ophthalmol. 2016 Feb;100(2):263-8. doi: 10.1136/bjophthalmol-2015-306656. Epub 2015 Jun 18. PMID 26089212

Identifiers

NCT: NCT02182921 · NSFC/YOUNG-81100653

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗