the Application of Cardiopulmonary Exercise Testing in Assessment Outcome of Patients With Pulmonary Hypertension
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: balloon pulmonary angioplasty.
- Who it may be relevant to
- Registry conditions: Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension Associated With Schistosomiasis (Disorder). Basic parameters: 5 years — 100 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
cardiopulmonary exercise test evaluate patients with pulmonary hypertension before and after medical or balloon pulmonary angioplasty treatment
Detailed description
patients diagnosed with pulmonary hypertension, including pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, will be evaluated by cardio pulmonary exercise test before and after medical or balloon pulmonary angioplasty treatment
Interventions
- Device balloon pulmonary angioplasty
patients with chronic thromboembolic pulmonary hypertension who underwent balloon pulmonary angioplasty
Primary outcome measures
- all cause mortality [Time frame: 5 years]
- mean pulmonary arterial pressure after treatment [Time frame: 5 years]
- achievement of low risk [Time frame: 5 years]
Secondary outcome measures (1)
- deterioration of WHO function [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- pulmonary arterial hypertension;( WHO1)
- chronic thromboembolic pulmonary hypertension;
- pulmonary arterial hypertension due to other cause;
Exclusion criteria
- massive hemoptysis;
- unable to accomplish cardiopulmonary exercise testing due to neuromuscular disorders;
- recent recurrent syncope;
- pulmonary hypertension due to hypoxia;
- pulmonary hypertension due to left heart diseases.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
China · 1 center
- center of pulmonary vascular disease, Fuwai hospital — Beijing
Publications
- Li X, Duan A, Jin Q, Zhang Y, Luo Q, Zhao Q, Yan L, Huang Z, Hu M, Xiong C, Zhao Z, Liu Z. Exercise feature and predictor of prognosis in patients with pulmonary artery stenosis-associated pulmonary hypertension. ESC Heart Fail. 2022 Dec;9(6):4198-4208. doi: 10.1002/ehf2.14154. Epub 2022 Sep 13. PMID 36101502
- Tang Y, Yao L, Liu Z, Ma X, Luo Q, Zhao Z, Huang Z, Tu L, Gao L, Jin Q, Ni X, Xiong C. Effect of calcium channel blockers evaluated by cardiopulmonary exercise testing in idiopathic pulmonary arterial hypertension responding to acute pulmonary vasoreactivity testing. Pulm Pharmacol Ther. 2017 Apr;43:26-31. doi: 10.1016/j.pupt.2017.01.012. Epub 2017 Feb 1. PMID 28159512
Identifiers
NCT: NCT02061787 · CPETPH