Analysis of Biomarkers From Patients With Chorioretinal Diseases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Chorioretinal diseases.
- Who it may be relevant to
- Registry conditions: Diabetic Retinopathy, Macular Degeneration. Basic parameters: 20 years — 80 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
This study was conducted to investigate the levels of ocular biomarkers from the patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
Detailed description
This prospective, case-control study included 50 patients(50eyes) with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration. and 50 patient with nondiabetic retinopathy or cataract. Ocular fluids and blood samples were taken before injection of anti-vascular endothelial growth factor agent or pars plana vitrectomy for other retinal disease. Ocular biomarkers were analyzed.
Interventions
- Drug Chorioretinal diseases
chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration
Primary outcome measures
- Biomarkers in ocular fluids [Time frame: one month]
Eligibility criteria
Inclusion criteria
- age over 20 years
- patients requiring ophthalmologic treatments for different degrees of decreasing of visual acuity.
- patients with chorioretinal diseases including diabetic retinopathy, retinal vascular diseases, age-related macular degeneration (dry and wet), and retinal degeneration.
- control patients asking cataract surgery or vitrectomy for posterior segment nonproliferative disorders.
Exclusion criteria
- under the age of 20 years
- patients that received any anti-vascular endothelial growth factor agent for proliferative disease before taking sample of aqueous humor
- patients that did not signed the informed consent of the trial
- patients with intraocular inflammations or infections that requiring any pharmaceutical agent
- patients with recent ocular trauma
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
South Korea · 1 center
- Dong Ho Park — Daegu
Identifiers
NCT: NCT02026843 · KNUH2013-1