Recruiting NCT01771718

Pilot Study on In-vivo Non-invasive Skin Imaging Using Multiphoton Microscopy

— Observational Skin Lesion

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied: The protocol lists: Multiphoton microscopy-based tomograph..
Who it may be relevant to: Registry conditions: Skin Lesion. Basic parameters: No limits · All.
What needs checking: Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place: United States
Next step: Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

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Official title

Non-invasive Skin Imaging Using Multiphoton Microscopy

Overview

The purpose of this pilot study is to employ multiphoton microscopy to non-invasively image in-vivo pigmented and non-pigmented human skin lesions for characterization of their morphologic and functional features.

Detailed description

This study is performed using a multiphoton microscopy-based tomograph (MPTflex) developed by JenLab, GmbH (Germany) and a MPM imaging system developed at BLI: Fast Large Area Multiphoton Exoscope (FLAME) to image non-invasively normal and lesional skin. Skin lesions are imaged by multiphoton microscopy and images are compared to those obtained from histopathology through standard of care processed skin biopsies.

Any biopsies will be performed by the health care provider as a standard of care procedure.

Interventions

Device Multiphoton microscopy-based tomograph.
non-invasive optical biopsy

Primary outcome measures

high-resolution images of skin [Time frame: up to 12 months]

Eligibility criteria

Inclusion criteria

Male or Female all age groups
Ability to understand and carry out subject instructions

Exclusion criteria

Pregnant women

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model: Case-only

Study locations

United States · 1 center

Beckman Laser Institute Medical Clinic — Irvine

Identifiers

NCT: NCT01771718 · 20118494 · R01EB026705

Primary sources (government registries)

ClinicalTrials.gov (US NIH)

View this study on ClinicalTrials.gov ↗