Collection of Blood for Multiple Collaborative Studies
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: HIV. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Collection and Preservation of Blood and Serum Specimens From HIV Positive or HIV Negative Patients for Multiple Collaborative Studies
Overview
This study seeks to confidentially collect blood from HIV-positive individuals and HIV-negative controls to provide basic scientists with specimens for collaborative studies.
Detailed description
HIV positive patients are currently the focus of multiple collaborative research studies, both at UCSF and other institutions. The aims of these research projects include improving the understanding of etiology, immunology, epidemiology and treatment of HIV. There are numerous requests from basic scientists at UCSF for collaborative studies on specimens, especially for blood, saliva and urine samples. Specimens may be used to test such things as virus characteristics, genotyping and/or phenotyping resistance, plasma drug concentrations, immune function or evidence of complications of HIV disease. The samples may also be tested for genetic factors that may be related to the course of HIV disease
Primary outcome measures
- Plasma HIV RNA level [Time frame: Ongoing]
Eligibility criteria
Inclusion criteria
- HIV-1 antibody negative with similar characteristics to HIV-1 positive cohort
- HIV-positive subjects naive to antiretroviral therapy
- HIV-positive subjects stable on or off antiretroviral therapy for a minimum of 6 months
- Good venous access
- Able to provide informed consent
Exclusion criteria
- Hemoglobin < 9g/dl
- Hematocrit < 27%
- Active treatment for cancer
- Hospitalization or IV antibiotic use within the last 4 months
- Immunosuppressive therapy within the last 4 months
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- San Francisco General Hospital — San Francisco
Identifiers
NCT: NCT01336855 · H8211-04743-22