Proteinuria in Pre and Post Transplant
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Proteinuria. Basic parameters: up to 25 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Evaluation of Recipients With and Without Proteinuria, Pre and Post Kidney Transplantation
Overview
Patients with focal segmental glomerulosclerosis (FSGS) who progress rapidly to end stage renal disease (ESRD) are at highest risk for development of recurrence of proteinuria following kidney transplantation. This study will look at serum specimens pre and post transplant, as well as kidney transplant specimens pre and post reperfusion to identify where the defects has occured that results in recurrence of proteinuria in a given kidney transplant.
Detailed description
This study will retrospectively review patient's medical records for protein in the urine, blood creatinine and kidney biopsy results. Also character of the fluid used to flush the kidney before transplant will be analyzed.
Primary outcome measures
- Explain mechanisms behind the development of proteinuria in patients immediately after receiving a kidney transplant [Time frame: through study completion, an average of 5 years]
Eligibility criteria
Inclusion criteria
- Kidney transplant recipients
- Pediatric males and females up to the age of 25 years old.
Exclusion criteria
- Transplant recipients other than kidney
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
United States · 1 center
- University of Miami Miller School of Medicine Transplant Clinic — Miami
Identifiers
NCT: NCT01094327 · 20070206