Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: biologic sample preservation procedure, medical chart review.
- Who it may be relevant to
- Registry conditions: Head and Neck Cancer. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Head and Neck Tumor Tissue Repository and Clinical Database
Overview
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.
Detailed description
OBJECTIVES:
* Maintain and update a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer. * Develop a repository of biospecimens from these patients.
OUTLINE: Tumor tissue samples and/or bronchial washings are collected from patients undergoing planned surgery and/or bronchoscopy, respectively. Buccal swabs and/or mouthwash samples and saliva samples are collected. Patients also undergo blood sample collection at baseline and then every 2-6 months thereafter.
Healthy participants contribute blood samples, buccal swabs, and mouthwash samples at baseline only.
Information about medical and family history and cancer risk factors is also collected.
PROJECTED ACCRUAL: No limit.
FOLLOW UP: Indefinite, until date of death or lost to follow up.
Interventions
- Other biologic sample preservation procedure
- Other medical chart review
Primary outcome measures
- Maintenance of a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer [Time frame: ongoing]
- Development of a repository of biospecimens [Time frame: ongoing]
Eligibility criteria
DISEASE CHARACTERISTICS:
- Meets 1 of the following criteria:
- Diagnosis of head and neck cancer
- Being treated at Vanderbilt University Medical Center for the cancer
- Healthy participant
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 4 centers
- Vanderbilt-Ingram Cancer Center - Cool Springs — Nashville
- Vanderbilt-Ingram Cancer Center at Franklin — Nashville
- Veterans Affairs Medical Center - Nashville — Nashville
- Vanderbilt-Ingram Cancer Center — Nashville
Identifiers
NCT: NCT00898638 · CDR0000546682 · P30CA068485 · VU-VICC-HN-0356 · VU-VICC-IRB-030062