Recruiting NCT07077174
Effects of PERMISSive Lung-protective Ventilation on Outcome in Critically Ill Invasively Ventilated Patients
Mechanical Ventilation · Intensive Care (ICU)
Lung cancer
3,760 trials in this section
Recruiting NCT06995898
The Vanguard Study: Testing a New Way to Screen for Cancer
Bladder Carcinoma · Breast Carcinoma · Colorectal Carcinoma
Recruiting NCT05543330
A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC
Malignant Pleural Effusions · NSCLC Stage IV
Recruiting NCT07314216
Firmonertinib Combined With Definitive Radiotherapy in Stage III Unresectable EGFR Uncommon Mutant Pulmonary Adenocarcinoma
NSCLC (Non-small Cell Lung Carcinoma) · Stage III · EGFR Uncommon Mutations
Recruiting NCT06465329
A Study of Cemiplimab Plus Chemotherapy Versus Cemiplimab Plus Chemotherapy Plus Other Cancer Treatments for Adult Patients With Operable Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer
Recruiting NCT07690917
A Study of a New PET Scanner in People With Cancer
Non Small Cell Lung Carcinoma NSCLC · Head and Neck Cancer · Prostate Cancer
Recruiting NCT07242547
Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients
Limited-stage Small-cell Lung Cancer · Carcinoma, Small Cell Lung · Respiratory Tract Neoplasms
Recruiting NCT07066813
Staging Strategies and Their Association With Prognosis and Therapy in Lung Cancer With Cystic Airspaces
Lung Cancer Associated With Cystic Airspaces
Not yet recruiting NCT07676383
Precision Navigation to Improve Community Cancer Screening Participation
Cancer Screening · Lung Cancer · Breast Cancer
Recruiting NCT07416695
A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of HLX3901 in Patients With Advanced SCLC or NEC
SCLC · NEC
Recruiting NCT07296887
CARE Tool Study Aim 3
Gynecologic Cancer · Prostate Cancer · Lung Cancer
Recruiting NCT07670013
SKB264 Plus Glecirasib in Advanced KRAS G12C-Mutant NSCLC: A Phase II Study
NSCLC
Recruiting NCT06931717
A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy
Non-Small Cell Lung Cancer
Recruiting NCT06996249
Prospective Data Collection Initiative on Thoracic Malignancies
Lung Cancer · Thoracic Cancer · Lung Cancer, Nonsmall Cell
Not yet recruiting NCT07686185
A Non-interventional, Real-world Study on the Adjuvant Treatment of Chinese EGFR-positive Stage IA NSCLC Patients With High-risk Factors Using Third-generation EGFR-TKIs.
Non-Small Cell Lung Cancer · Adjuvant Therapy
Recruiting NCT07518160
JS212 Plus JS111 in EGFR-Mutant Advanced NSCLC: A Phase II Study
Locally Advanced, Metastatic, or Recurrent Non-small Cell Lung Cancer (NSCLC) Harboring Epidermal Growth Factor Receptor (EGFR) Mutations
Recruiting NCT05424029
Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Not yet recruiting NCT07364682
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography
Premature Baby · Pulmonary Hypertension of Newborn · Hypoxic Ischaemic Encephalopathy (HIE)
Recruiting NCT06552234
Phase II Efficacy Study of Repotrectinib in Frail and/or Elderly Patients With ROS1-rearranged Advanced NSCLC
NSCLC Stage IV · NSCLC, Stage III
Recruiting NCT07358039
Effect of Post-suction Recruitment on Lung Volume in Mechanically Ventilated ICU Patients
Mechanical Ventilation
Not yet recruiting NCT07688577
XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors
Metastatic NSCLC - Non-Small Cell Lung Cancer · Advanced Solid Tumor
Recruiting NCT07117214
A Phase I Study of [68Ga]Ga-DWJ155 in Patients With Breast and Lung Cancers
Breast Neoplasms · Carcinoma, Non-Small-Cell Lung
Not yet recruiting NCT07686549
Patient-Specific 3D Model-Assisted Preoperative Consultation for Thoracoscopic Lung Resection
Lung Neoplasms · Thoracoscopic Lung Resection · Shared Decision Making
Not yet recruiting NCT07507435
Optimizing Medications and Lung Health in People With HIV Through Pharmacist-led Proactive E-Consults
HIV · Inhaled Corticosteroid · Proton Pump Inhibitor
Recruiting NCT06825715
Multilevel Intervention for Precision Oncology
Advanced Cancers of the Prostate · Cancers of the Lung
Recruiting NCT07115043
A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors
Melanoma · Non-small Cell Lung Cancer · Squamous Cell Carcinoma (Skin)
Recruiting NCT07681245
Label-free Femtosecond Laser Imaging Combined With the Fast Lung Artificial Intelligence Model for Rapid Intraoperative Diagnosis of Lung Surgical Specimens: A Multicentre, Prospective, Parallel-workflow, Non-inferiority Study.
Lung Cancer
Recruiting NCT06699979
Multi-omics Study of Early-stage Lung Cancer With Distinct Phenotypes
Lung Cancer Associated With Cystic Airspaces · Multiple Primary Lung Cancers · Non-Small Cell Lung Cancer
Recruiting NCT06116786
A Study of JNJ-86974680 in Participants With Advanced Non-small Cell Lung Cancer
Carcinoma, Non-small-Cell Lung
Not yet recruiting NCT07685938
Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease
Chest Wall Tumor · Breast Cancer · Lung Cancer
Recruiting NCT06925373
Housing, Environment, And Living Conditions for Transformed Health
Lung Diseases · Chronic Disease
Recruiting NCT05248230
4D-710 in Adult Patients With Cystic Fibrosis
Cystic Fibrosis Lung
Recruiting NCT06535607
Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy) · Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy) · Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy)
Recruiting NCT07538804
A Study to Investigate ANS02 in Participants With EGFR Mutation-Positive Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Recruiting NCT06667908
A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)
Carcinoma, Non-Small-Cell Lung
Recruiting NCT07645222
PHASE 1b STUDY OF HS-20122 COMBINED THERAPY IN NSCLC
Lung Cancer
Not yet recruiting NCT07685041
An Open-label, Fixed-sequence Phase I Clinical Trial to Evaluate the Effect of HS-10504 on the Pharmacokinetics of Midazolam in Patients With Non-small Cell Lung Cancer
NSCLC
Recruiting NCT04389632
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
Carcinoma, Non-Small Cell Lung · Squamous Cell Carcinoma of Head and Neck · HER2 Negative Breast Neoplasms
Recruiting NCT06780137
A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)
Small Cell Lung Cancer
Recruiting NCT06452277
A Study to Learn More About How Well Sevabertinib Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Advanced Non-small Cell Lung Cancer, HER2 Mutation
Recruiting NCT07300150
A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors
Colorectal Cancer · Pancreatic Cancer · Non-Small Cell Lung Cancer
Recruiting NCT07423585
Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer
Extensive Stage Lung Small Cell Carcinoma
Recruiting NCT06710756
Lead-212 PSV359 Therapy for Patients With Solid Tumors
Pancreatic Ductal Adenocarcinoma · Gastric Cancer · Esophageal Cancer
Recruiting NCT07177937
A Study of DXC014 in Patients With Advanced Solid Tumors.
Small Cell Lung Cancer · Melanoma · Prostate Cancer
Recruiting NCT07462377
A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC
Epidermal Growth Factor · Epidermal Growth Factor Receptor · Epidermal Growth Factor Receptor Gene Mutation
Recruiting NCT06601998
Cardiovascular Disease Progression in Survivors of Community Acquired Pneumonia and Lung Infection by Covid-19.
Pneumonia, Community-Acquired · COVID-19 Pneumonia · Cardiovascular Diseases
Not yet recruiting NCT07683832
Safety, Tolerability, Immunogenicity, Pharmacodynamic Characteristics, and Preliminary Anti-tumor Activity of Personalized Cancer Vaccines Alone and in Combination With Toripalimab in Participants With Resected NSCLC
Non-Small Cell Lung Cancer NSCLC
Not yet recruiting NCT07685197
Comparative ¹⁸F-FDG and ⁶⁸Ga-MY6349 PET/CT Imaging for Assessing TROP2 ADC Therapeutic Efficacy in EGFR-TKI Resistant Advanced NSCLC
NSCLC · EGFR Activating Mutation · EGFR-TKI-resistant Non-Small Cell Lung Cancer
Recruiting NCT05819944
A Trial Evaluating Novel Technologies for the Diagnosis of Asthma The LUNG-TECH Trial
Asthma
Recruiting NCT07682597
Statewide Optimization of Lung Cancer Screening Utilizing the QUILS™ System in Nevada and Mississippi: State-Based Initiative Component
Lung Cancer Screening
Recruiting NCT05498428
A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer
Carcinoma, Non-small-Cell Lung
Recruiting NCT05696782
Quick Start Durvalumab Following Chemoradiation for Stage III Nonsmall Cell Lung Cancer
Nonsmall Cell Lung Cancer Stage III · Unresectable Non-Small Cell Lung Carcinoma · Nonsmall Cell Lung Cancer, Stage II
Recruiting NCT06780085
A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)
Carcinoma, Non-Small-Cell Lung
Recruiting NCT07358676
A Study of Bemotuzumab Plus Chemotherapy and Anlotinib Induction Followed by Bemotuzumab, Anlotinib and Consolidative Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer
Small Cell Lung Cancer (SCLC) · SCLC, Extensive Stage
Recruiting NCT07682610
Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Health Services Research Intervention
Lung Cancer Screening
Recruiting NCT07595926
Height Measurement Procedures Influence the Risk of Ventilator-induced Lung Injury in ARDS
Acute Respiratory Distress Syndrome · Ventilator-Induced Lung Injury · Tidal Volume
Recruiting NCT06488638
Pilot Study of Nitrate-rich Beetroot Juice Supplementation in Patients With Idiopathic Pulmonary Fibrosis (IPF)
Idiopathic Pulmonary Fibrosis · Interstitial Lung Disease
Not yet recruiting NCT07685028
LEGACY: Lung Cancer Screening in Individuals With a Lung Cancer Family History-Protocol A
Family History of Lung Cancer
Recruiting NCT06595602
Intelligent Lung Support in the Intensive Care Unit
Mechanical Ventilation · Intensive Care Medicine
Recruiting NCT06839105
A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies
Non-Small Cell Lung Cancer, Colorectal Cancer, Renal Cell Carcinoma, Melanoma and Other Solid Tumor
Recruiting NCT07482917
Optimizing the Diagnostic Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-1 Trial
Interstitial Lung Disease (ILD) · Suspected Interstitial Lung Disease · Fibrotic Interstitial Lung Disease
Not yet recruiting NCT07639242
Olomorasib + Pembrolizumab KRAS G12C Mutant, PD-L1 TPS 1-49% Locally Advanced or Metastatic NSCLC
Lung Cancer · Lung Cancer (NSCLC) · Locally Advanced NSCLC
Recruiting NCT06876766
Effect of Pediatric Lung Ultrasound on Antibiotic Prescriptions in Hospitalized Children and Adolescents With Lower Respiratory Tract Infections. A Randomized Controlled Trial.
Lower Resp Tract Infection
Recruiting NCT06066723
19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
Cystic Fibrosis in Children
Recruiting NCT07169734
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
Cervical Squamous Cell Carcinoma · Squamous Non-small-cell Lung Cancer · Colorectal Cancer
Recruiting NCT07681583
Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score
Pneumonia · Fungal Pneumonia · Aspergillosis Pneumonia
Not yet recruiting NCT07682168
DIVision of the Interlobar Fissure in Patients Who Do Not Respond to Endobronchial Lung Volume Reduction
Chronic Obstructive Pulmonary Disease (COPD) · Emphysema · Lung Volume Reduction Surgery
Recruiting NCT06927986
Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01）
EGFR-mutated Locally Advanced or Metastatic NSCLC
Recruiting NCT07291037
Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations
Non-small Cell Lung Cancer (NSCLC)
Recruiting NCT07676435
Ongoing Lung Decline With Age Intensified Response
Age-Related Lung Function Decline
Recruiting NCT07098988
Trial Investigating Visugromab in Combination With Immunochemotherapy in 1L Treatment of Participants With Metastatic NSCLC
Metastatic Non-Squamous Non-Small Cell Lung Cancer · Adult Solid Tumor
Not yet recruiting NCT07679607
GCC 2545- Improving Post-Radiotherapy Respiratory Function Through Sparing Serial and Parallel Components in the Lung
Lung Cancer (NSCLC) · Radiation
Recruiting NCT06712316
Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer
Non-small Cell Lung Cancer
Recruiting NCT04804644
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability
Metastatic Lung Small Cell Carcinoma · Metastatic Malignant Neoplasm in the Brain · Recurrent Lung Small Cell Carcinoma
Recruiting NCT07432477
Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
Atelectasis, Postoperative
Recruiting NCT07677787
DLL3-Targeted PET/CT in Small Cell Lung Cancer
PET/CT · Small Cell Lung Cancer ( SCLC ) · DLL3-targeted PET/CT
Not yet recruiting NCT07675876
Inhaled Cromolyn Sodium in Patients With Locally Advanced Lung Cancer
Locally Advanced Non-Small Cell Lung Cancer · Lung Adenocarcinoma
Recruiting NCT07186296
EXoPERT EMERALD Clinical Study
Breast Cancer · Colon Cancer · Pancreatic Cancer
Recruiting NCT00568490
Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
Head and Neck Cancer · Lung Cancer · Lip Cancer
Recruiting NCT06985225
Evaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Muco-Obstructive Lung Disease
Severe Asthma · COPD · Non-CF Bronchiectasis
Recruiting NCT07639255
Kentucky - Quality Improvement Implementation Lung Cancer Screening (QUILS™) Implementation
Lung Cancer Screening
Recruiting NCT07307066
Real-Time Algorithm-Driven Ventilation Feedback to Improve Lung-Protective Ventilation in Patients With ARDS (REALVENT-study)
ARDS (Acute Respiratory Distress Syndrome) · VILI (Ventilator-induced Lung Injury) · Respiratory Failure
Not yet recruiting NCT07678320
AI Technologies for Enhanced and Celerated High-Field WB-MRI
Whole Body Imaging · Prostate · MRI
Recruiting NCT07098338
A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)
Non-Small Cell Lung Cancer
Not yet recruiting NCT07674368
Rucaparib Monoclonal Antibody for Lorlatinib-Induced Hypercholesterolemia / Mixed
ALK Fusion-positive Non-small Cell Lung Cancer
Recruiting NCT05099172
First in Human Study of BAY2927088 in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations in the Genes of Epidermal Growth Factor Receptor (EGFR) and/or Human Epidermal Growth Factor Receptor 2 (HER2)
Advanced Non-small Cell Lung Cancer · EGFR Mutation · HER2 Mutation
Recruiting NCT05443126
A Study of EP0031 (Lunbotinib) in Patients With Advanced RET-altered Malignancies
NSCLC
Recruiting NCT07609121
Hypofractionated Chemoradiotherapy With Tislelizumab and Surufatinib for Unresectable Stage III NSCLC
NSCLC (Non-small Cell Lung Cancer)
Recruiting NCT06772025
A Study to Understand How Cardiac Surgery-associated Acute Kidney Injury Develops in Participants Who Undergo Heart Surgery With the Use of Heart-lung Machine
Cardiac Surgery-associated Acute Kidney Injury
Recruiting NCT05136846
Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer
Locally Advanced Lung Non-Small Cell Carcinoma · Stage II Lung Cancer AJCC v8 · Stage IIA Lung Cancer AJCC v8
Recruiting NCT06162221
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
Non-Small Cell Lung Cancer, NSCLC · KRAS, NRAS, HRAS-mutated NSCLC · KRAS G12C-mutated Solid Tumors, Lung Cancer
Recruiting NCT07674953
How Different Levels of CPAP Affect Oxygen Delivery and Lung Expansion in Preterm Infants
Respiratory Distress Syndrome (Neonatal) · Respiratory Distress of Newborn
Recruiting NCT05965557
Exploration of Predictive Markers of Neoadjuvant Immunotherapy in Non-Small Cell Lung Cancer
Lung Cancer
Recruiting NCT07652125
RGL-270 + ICI in Advanced NSCLC
NSCLC
Recruiting NCT07675473
Pre-Emptive Parecoxib Sodium for Pain Control During CT-Guided Lung Nodule Localization
Lung Nodules
Recruiting NCT04895709
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Cervical Cancer · Gastric/Gastroesophageal Junction Adenocarcinoma · Microsatellite Stable Colorectal Cancer
Not yet recruiting NCT07675889
Intraoperative Longitude-Latitude-Depth Localization Versus Preoperative CT-Guided Percutaneous Lung Puncture Localization for 0.8-2 cm Peripheral Pulmonary Nodules
Pulmonary Nodule, Solitary · Peripheral Pulmonary Nodules · Pulmonary Nodules
Recruiting NCT07673861
Clinical Utility of ctDNA in Detecting Resistance Mechanisms and Delivering Precision Medicine to Cancer Patients
Non Small Cell Lung Cancer · Gastrointestinal Stromal Tumor (GIST) · Colorectal Cancer
Recruiting NCT07285655
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Pulmonary Hypertension Due to Lung Disease (Disorder)
Not yet recruiting NCT07673419
A Clinical Study GK01 Cell Injection in Subjects With Advanced Lung Cancer
Advanced Lung Cancer