Lung cancer

Not yet recruiting NCT06670118☆ Save

Exploring the Correlations of Lung Ultrasound with Delirium and Outcomes in Acute GEriatrics World: a Multicenter, Prospective, Observational Study from the GRETA Group of the Italian Society of Gerontology and Geriatrics

— Observational Italy

Acute Respiratory Failure · Delirium in Old Age · Pneumonia

Recruiting NCT06667154☆ Save

Efficacy Analysis of Neoadjuvant Treatment in Lung Cancer Using Low-dose Nivolumab Combined With Chemotherapy

Phase II Interventional Brazil

Lung Cancer, Nonsmall Cell · Non-Small Cell Lung Cancer NSCLC

Recruiting NCT05468242☆ Save

Study of Tislelizumab for Locally Advanced Non-Small Cell Lung Cancer Following Neoadjuvant Chemotherapy Plus Tislelizumab ± Bevacizumab and Definitive Concurrent Chemoradiation Therapy

Phase II Interventional China

Stage III Non-small Cell Lung Cancer

Recruiting NCT05403554☆ Save

A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers

Phase I Interventional France, Italy

Epithelial Ovarian Cancer · Triple Negative Breast Cancer · Non-squamous Non-small-cell Lung Cancer

Recruiting NCT06444854☆ Save

Patient Reported Outcomes Targeting Early Chest Tube Removal (PROTECTR) Study

No phase Interventional Canada

Lung Surgery · Chest Tube Removal · Enhanced Recovery After Surgery (ERAS)

Recruiting NCT05772455☆ Save

A Study of XZB-0004 in Patients With Solid Tumors

Phase I Interventional China

Advanced Solid Tumor · NSCLC

Recruiting NCT06657898☆ Save

Complicated Pneumonia (CP) in Children in South-East Europe

— Observational Serbia

Pneumonia, Necrotizing · Lung Abscess · Empyema, Pleural

Recruiting NCT06107374☆ Save

Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

Phase II Interventional United States

Advanced Non Small Cell Lung Cancer

Recruiting NCT06084806☆ Save

Test-retest Evaluation of [18F]F-AraG PET

Phase II Interventional United States

Non-small Cell Lung Cancer

Recruiting NCT06655090☆ Save

Fibrotic Interstitial Lung Disease Early Recognition and Strategic Therapy Study in China

— Observational China

Interstitial Lung Disease (ILD)

Enrolling by invitation NCT06448988☆ Save

Evaluation of Respiratory Mechanics in Supine and PARK-bench Positions (SPARK)

— Observational Italy

Ventilation Therapy; Complications · Ventilator-Induced Lung Injury

Recruiting NCT04335292☆ Save

Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer with Osimertinib Third-line Rechallenge

Phase II Interventional Canada

Non-Small Cell Lung Cancer

Recruiting NCT06653478☆ Save

Development and Demonstration of Intelligent Assessment Based on Multi-modal Information Fusion for Tumor Risk and Diagnosis and Treatment

— Observational China

Artificial Intelligence · Deep Learning · Lung Cancer

Recruiting NCT04322890☆ Save

Treatment Strategies and Survival Outcome for Non-small Cell Lung Cancer With Oncogenic Mutation

Phase II Interventional China

Non Small Cell Lung Cancer · EGFR Gene Mutation · ALK Gene Mutation

Not yet recruiting NCT06652555☆ Save

The Incidence and Risk Factors of Central Nervous System Adverse Events of Lorlatinib in Patients with ALK-positive Advanced Non-small Cell Lung Cancer: a Real-world Study

— Observational —

ALK · NSCLC

Recruiting NCT06182748☆ Save

Physical Activity and Fibrosing Interstitial Lung Disease

No phase Interventional France

Fibrotic Interstitial Lungs Diseases

Recruiting NCT05925764☆ Save

WSI Based DL for Diagnosing the IASLC Grading System of Lung Adenocarcinoma

— Observational China

Lung Adenocarcinoma · Whole Slide Image · IASLC Grading System

Not yet recruiting NCT06531343☆ Save

Advancing Lung Cancer Screening: Artificial Intelligence, Multimodal Imaging and Cutting-Edge Technologies for Early Detection and Characterization

No phase Interventional Italy

Lung Cancer Screening

Recruiting NCT01993498☆ Save

Chronic Toxicities Related to Treatment in Patients With Localized Cancer

No phase Interventional France

Breast Cancer Nos Metastatic Recurrent · Early Lung Cancer

Not yet recruiting NCT06648200☆ Save

Toripalimab and JS004 Combined With Platinum-based Chemotherapy for Relapsed and Extensive-stage Small Cell Lung Cancer

Phase II Interventional China

Small Cell Lung Cancer Extensive Stage · Small Cell Lung Cancer Recurrent

Not yet recruiting NCT06645743☆ Save

Retrospective Analysis of Clinical and CT Features to Predict Spread Through Air Space in Stage IA Lung Adenocarcinoma

— Observational China

Tomography, X-Ray Computed · Spread Through Air Space · Clinical Features

Not yet recruiting NCT06646770☆ Save

SEgmentectomy Versus Lobectomy in T1C Non-Small Cell Lung Cancer (SELTIC)

No phase Interventional Turkey (Türkiye)

Non-Small Cell Lung Cancer

Recruiting NCT05501665☆ Save

Split Course Adaptive Radiation Therapy With Pembrolizumab With/Without Chemotherapy for Treating Stage IV Lung Cancer

Phase I / Phase II Interventional United States

Lung Non-Small Cell Carcinoma · Stage IV Lung Cancer AJCC v8 · Stage III Lung Cancer

Recruiting NCT06645977☆ Save

Patients With Interstitial Lung Disease

— Observational Italy

Interstitial Lung Disease

Not yet recruiting NCT06647147☆ Save

Aerobic Training on Lung Function in Fibromyalgia

No phase Interventional —

Fibromyalgia (FM) · Respiration Disorders

Not yet recruiting NCT06644495☆ Save

Post-Market Surveillance Study of ALK-Positive Advanced NSCLC Participants Treated With Iruplinalkib

— Observational —

NSCLC

Recruiting NCT04605146☆ Save

Impact of Telemonitoring for the Management of Side Effects in Patients with Melanoma, Lung or Renal Cancer, Treated with Immunotherapy Combination of Nivolumab and Ipilimumab or Adjuvant Nivolumab Monotherapy

No phase Interventional France

Melanoma · Lung Cancer · Renal Cancer

Recruiting NCT06498479☆ Save

ARTEMIS-008：HS-20093 Compared With Topotecan in Subjects With Relapsed Small Cell Lung Cancer

Phase III Interventional China

Small Cell Lung Cancer

Recruiting NCT06302985☆ Save

Atomized Inhalation ICG for Treatment of Congenital Lung Malformations

No phase Interventional China

Pulmonary Sequestration · Congenital Pulmonary Airway Malformation · Indocyanine Green

Not yet recruiting NCT06644313☆ Save

Vebreltinib for Neoadjuvant in MET-altered Stage IIIA-IIIB (N2) Non-small Cell Lung Cancer (NSCLC)

Phase II Interventional —

Potentially Resectable MET-altered Non-Small Cell Lung Cancer

Not yet recruiting NCT06643910☆ Save

A Study on the Safety and Efficacy of BST08 in Treating Advanced Non-Small Cell Lung Cancer

No phase Interventional China

Non-small Cell Lung Cancer

Recruiting NCT06638515☆ Save

Effects of Walking Apnea At Low Lung Volume on Hypoalgesia

No phase Interventional Spain

Pain · Hypoxemia · Hypercapnia

Recruiting NCT06638528☆ Save

Effects of Walking Apnea At High Lung Volume on Hypoalgesia

No phase Interventional Spain

Pain · Hypoxemia · Hypercapnia

Recruiting NCT06637345☆ Save

Identification of Prognostic and Predictive Biomarkers of Toxicity in Patients With Malignant Pleural Mesothelioma and Treated With High Doses of Radiotherapy (MESORTIBO)

— Observational Italy

Pleural Mesothelioma Malignant

Not yet recruiting NCT06597513☆ Save

Auto-HSCT-Supported Dose-Dense Chemotherapy with Adebrelimab As First-Line Treatment for ES-SCLC

Phase I / Phase II Interventional —

Extensive Stage Small Cell Lung Cancer

Recruiting NCT05902559☆ Save

Assessment of Novel Biomarkers in Participants Undergoing Targeted Lung Health Checks

— Observational United Kingdom

Lung Cancer

Not yet recruiting NCT06641609☆ Save

A Phase I Study of CFT8919 in Patients With Advanced NSCLC

Phase I Interventional China

Non-Small Cell Lung Cancer With EGFR Mutation

Recruiting NCT06607770☆ Save

Safety and Efficacy of Cryoablation With Karelizumab and Apatinib for Multiple Lung Cancers

Phase I / Phase II Interventional China

Lung Cancer

Recruiting NCT05487391☆ Save

A Study of QL1706 Combined With Platinum-containing Chemotherapy in Adjuvant Treatment of Stage II-IIIB Non-small Cell Lung Cancer After Complete Surgical Resection.

Phase III Interventional China

Carcinoma, Non-Small-Cell Lung

Recruiting NCT05745961☆ Save

Quantifying 18kDa TSPO Expression in the Lung in Pulmonary Artery Hypertension (PAH)

— Observational United Kingdom

Pulmonary Arterial Hypertension · Healthy

Enrolling by invitation NCT06028412☆ Save

Comparison of Sublobar and Lobectomy in Small (2 Cm or Less 0.5<CTR<1) Non-small Cell Lung Cancer: a Prospective, Multicenter Randomized Controlled Study

No phase Interventional China

NSCLC, Stage I

Recruiting NCT06634966☆ Save

Segmentectomy for Solid-dominant Lung Cancer

Phase III Interventional China

Segmentectomy · Lung Adenocarcinoma

Not yet recruiting NCT06634667☆ Save

Third-generation EGFR-TKI Plus Anlotinib as Maintenance for NSCLC With Small Cell Transformation After EGFR-TKI Resistance

Phase II Interventional China

Non-small Cell Lung Cancer

Recruiting NCT06632886☆ Save

AI-Assisted Non-Contrast CT for Multi-Cancer Screening

No phase Interventional China

Lung Cancers · Liver Cancer · Gastric Cancers

Not yet recruiting NCT06196814☆ Save

AK112 Plus Platinum-based Chemotherapy for EGFR/ALK/ROS1 Positve NSCLC

Phase I / Phase II Interventional —

Efficacy

Recruiting NCT02299921☆ Save

Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure

— Observational United States

Infection · Alcohol Abuse · Drugs of Abuse

Recruiting NCT05878964☆ Save

Evaluation of Skin Health and QoL in Pts Receiving Anti-PD1/PDL1/CTLA4 or CDK Inhibitors.

— Observational Italy

Lung Cancer · Breast Cancer · Kidney Cancer

Recruiting NCT06628102☆ Save

Improving Detection of Early Lung Cancer in a Diverse Population (IDEAL) Study

No phase Interventional Canada

Lung Cancer · Pulmonary Nodule

Recruiting NCT05751447☆ Save

Sarcoidosis and Immune Cells in Lung, Lymph Nodes and Blood

No phase Interventional Sweden

Sarcoidosis

Not yet recruiting NCT06603675☆ Save

Microplastics in the Human Respiratory System

— Observational Poland

Microplastics · Lung Cancer (NSCLC) · Lung Transplantation

Recruiting NCT06626178☆ Save

Development of an Artificial Intelligence Model for the Identification and Prevention of Smoking-related Diseases.

No phase Interventional Italy

Lung Cancer Screening Program · Artificial Intelligence (AI)

Recruiting NCT06623487☆ Save

The Application Value of 68Ga-grazytracer PET in Immunotherapy for Stage III Non-small-cell Lung Cancer

— Observational China

Carcinoma, Non-Small-Cell Lung · PET / CT · Neoadjuvant Immunotherapy

Not yet recruiting NCT06622174☆ Save

Pulse Radiotherapy to Overcome Metastatic Immune System Evasion in Lung Cancer

Phase I Interventional Canada

Non Small Cell Lung Cancer · Metastatic Lung Cancer

Not yet recruiting NCT06623786☆ Save

Cancer Patient Remote Monitoring for Timely Communication Study

— Observational —

NSCLC Stage IV

Recruiting NCT04611867☆ Save

Study of PRO in Patients with Advanced Pancreatic or Biliary Tract Cancer (BetterEveryDay)

No phase Interventional Denmark

Pancreatic Cancer · Lung Cancer, Nonsmall Cell

Not yet recruiting NCT06618391☆ Save

Local Injection and Systemic Therapy in the Treatment of NSCLC.

Phase II Interventional —

Non-small Cell Lung Cancer

Not yet recruiting NCT06620796☆ Save

A Phase II Study of Ivonescimab Combined with Cadonilimab and Chemotherapy in Extensive-stage Small Cell Lung Cancer

Phase II Interventional —

SCLC, Extensive Stage

Not yet recruiting NCT06620822☆ Save

Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial

Phase II Interventional China

Non Small Cell Lung Cancer

Recruiting NCT06341543☆ Save

Quantiferon CMV to Identify Treatment Need for Asymptomatic CMV Infection After Solid Organ Transplant (QUANTIFOT)

No phase Interventional France

Cytomegalovirus Infections · Heart Transplantation · Kidney Transplantation

Recruiting NCT04888429☆ Save

Camrelizumab Plus Famitinib as Treatment in Patient With Advanced or Metastatic Pulmonary Sarcomatoid Carcinoma

Phase II Interventional China

Sarcomatoid Carcinoma of Lung

Recruiting NCT06247163☆ Save

PET-guided Radiotherapy for Patients With Small Cell Lung Cancer.

— Observational Germany

Small Cell Lung Carcinoma

Not yet recruiting NCT06615128☆ Save

Assessment of Serum CD25 Level in Systemic Sclerosis Patients with or Without Interstitial Lung Disease (ILD)

— Observational —

Assessment of Serum Level of SCD25 in RA, SSc (with or Without ILD) and IPF and Its Correlation with Disease Activity

Not yet recruiting NCT06614231☆ Save

Neoajuvant Tislelizumab Combined with Chemotherapy for Initially Unresectable Stage IIIA/N2 Non-small Cell Lung Cancer

Phase II Interventional —

NSCLC, Stage IIIA · NSCLC (non-small Cell Lung Cancer)

Not yet recruiting NCT06614621☆ Save

A Study of Adebelimab Combined With Chemotherapy as a First-line Treatment Sequential Treatment for Extensive-stage Small Cell Lung Cancer

Phase II Interventional —

Extensive-Stage Small Cell Lung Cancer

Not yet recruiting NCT06613308☆ Save

Association Between Microbiome and the Efficacy and Safety of PD-1/PD-L1 Blockade in Resectable NSCLC

— Observational —

Lung Cancer (NSCLC)

Recruiting NCT06607796☆ Save

Efficacy and Safety of Intratumoral Toluenesulfonamide (PTS) Injection in Stage IV Driver Gene-Negative NSCLC With/Without Chemoimmunotherapy

Phase III Interventional China

Lung Cancer

Recruiting NCT05557552☆ Save

Sequential Chemo-immunotherapy Plus Thoracic Radiotherapy for Elderly And/or Frail Stage III Non-small-cell Lung Cancer

No phase Interventional China

Non-small Cell Lung Cancer Stage III

Recruiting NCT05974475☆ Save

MONDRIAN: Multi-omics Integrative Modelling for Stereotactic Body Radiotherapy in Early-stage Non-small Cell Lung Cancer

— Observational Italy

Lung Neoplasm Malignant

Not yet recruiting NCT06607926☆ Save

Neoadjuvant With Tα1 Plus Immuno-chemotherapy for Resectable NSCLC

No phase Interventional China

Resectable Non-Small-Cell Lung Cancer

Recruiting NCT06608160☆ Save

68Ga-grazytracer PET Assists in Diagnosing Pseudoprogression Following Immunotherapy in Lung Cancer.

— Observational China

PET / CT · Lung Carcinoma · Immunotherapy

Recruiting NCT05991193☆ Save

A Study With Central Nervous System Metastatic EGFR Mutation Positive Non-small Cell Lung Cancer

— Observational China

NSCLC

Not yet recruiting NCT06537297☆ Save

Intrathecal Pemetrexed Combined With High-dose Furmonertinib and Beva for EGFR-m NSCLC With Leptomeningeal Metastases

Phase II Interventional China

Non-small Cell Lung Cancer

Recruiting NCT06355609☆ Save

Sunvozertinib Plus Anlotinib as 1L Treatment in EGFR Mutant Advanced NSCLC-RW

Phase II Interventional China

Non-small Cell Lung Cancer

Recruiting NCT05014464☆ Save

ALK Tyrosine Kinase Inhibitors in ALK-rearranged Advanced Squamous Cell Carcinoma

Phase II Interventional China

Non-small Cell Lung Cancer

Not yet recruiting NCT06602661☆ Save

Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy

Phase I Interventional Canada

Lung · Lung Adenocarcinoma · Lung Adenosquamous Carcinoma

Not yet recruiting NCT06591910☆ Save

Induction Therapy With Serplulimab Combined With Chemotherapy for Unresectable Stage III Non-small Cell Lung Cancer

— Observational —

Unresectable Stage III Non-small-cell Lung Cancer

Not yet recruiting NCT06497543☆ Save

Intrathecal Pemetrexed for SCLC Patients With Refractory Brain Metastases or Leptomeninges Metastatic

Phase II Interventional China

Small-cell Lung Cancer

Recruiting NCT04777175☆ Save

A Retrospective Study: Evaluation of the Efficacy of Immunotherapy With Rare Mutations in Non-small Cell Lung Cancer

— Observational China

Non Small Cell Lung Cancer

Recruiting NCT05830812☆ Save

Improving the Intraoperative Diagnosis Accuracy of Invasiveness for Small-sized Lung Adenocarcinoma

— Observational China

Lung Adenocarcinoma, Stage I

Recruiting NCT04144569☆ Save

PD-1 Combined With Pyrotinib for Chemotherapy Failure HER2 Insertion Mutation Advanced NSCLC

Phase II Interventional China

HER2 Insertion Mutation Positive Advanced NSCLC

Recruiting NCT04324151☆ Save

Pembrolizumab Combined With Double Platinum Based Chemotherapy for Potentially Resectable NSCLC

— Observational China

Non Small Cell Lung Cancer

Recruiting NCT06141226☆ Save

Phase II Clinical Trial to Evaluate the Safety and Efficacy of TQB2450 Injection Combined With Anlotinib Capsule and Chemotherapy in the Treatment of Immunoresistant Advanced Non-small Cell Lung Cancer

Phase II Interventional China

Non-small-cell Lung Cancer

Recruiting NCT06603350☆ Save

The Effect of Perioperative Factors on Postoperative Outcomes After Lung Transplantation

— Observational China

Postoperative Complications After Lung Transplantation

Recruiting NCT06592235☆ Save

Awareness of Individuals with Chronic Lung Disease About Climate Change, Heat Waves, Air Pollution and Physical Activity

— Observational Turkey (Türkiye)

Climate Change · Chronic Lung Disease · Air Pollution

Recruiting NCT06595043☆ Save

Effects of Different Occlusion Angles of Disposable Tracheal Blocker on Right One-lung Ventilation

No phase Interventional China, Serbia +1

The Direction of Blocker Placement

Recruiting NCT05379803☆ Save

High-dose Furmonertinib for First-line Treatment of EGFR Mutated NSCLC With Central Nervous System (CNS) Metastases

Phase II Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT06527898☆ Save

Hypofractionated Radiotherapy Combined with Immunotherapy for Limited-stage Small-cell Lung Cancer

Phase I / Phase II Interventional China

Small-cell Lung Cancer

Not yet recruiting NCT06586060☆ Save

Lung Ultrasound Guided Fluid Balance Strategy in Patients with Lung Contusion

No phase Interventional Egypt

Lung Contusion

Recruiting NCT06105177☆ Save

Implementation of Up-front ctDNA Into Lung Cancer Care and Development of Liquid Biopsy-based Decision Support Models - LM² Study

— Observational Netherlands

Lung Cancer

Recruiting NCT04324125☆ Save

Chemotherapy Combined With Immunotherapy in HER 2 Insertion or Amplification Advanced NSCLC

— Observational China

Non Small Cell Lung Cancer

Recruiting NCT05552846☆ Save

Phase II Trial of Consolidative Thoracic Radiotherapy for ES-SCLC After Standard Care of Chemo-immunotherapy

No phase Interventional China

Small-cell Lung Cancer

Recruiting NCT06598839☆ Save

Immuno-effect of Tα1 for Stage I NSCLC

No phase Interventional China

Non Small Cell Lung Cancer

Not yet recruiting NCT06600503☆ Save

The Effect of a Mobile Application on Enhancing Pulmonary Rehabilitation After Lung Cancer Surgery

No phase Interventional —

Pulmonary Rehabilitation · Telerehabilitation · Lung Cancer

Not yet recruiting NCT06586801☆ Save

The Patient-Reported Outcomes in ALK Positive Advanced NSCLC in China

— Observational —

Non-small Cell Lung Cancer

Not yet recruiting NCT06604351☆ Save

Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction

Phase II Interventional China

Non-Small Cell Lung Cancer

Recruiting NCT05766800☆ Save

Induction Therapy With PD-1 Antibody Combined With Platinum-based Doublet Chemotherapy for Locally-advanced Non-small Cell Lung Cancer

Phase II Interventional China

Locally Advanced · Non-small Cell Lung Cancer

Not yet recruiting NCT06592430☆ Save

The Impact of Communication With Healthcare Providers Via WeChat on Survival Outcomes for Lung Cancer Patietns

— Observational —

Lung Cancer

Recruiting NCT05295212☆ Save

Atezolizumab Combined With Platinum-based Chemotherapy as Neoadjuvant Therapy for Patients With Resectable Stage II-IIIB

Phase II Interventional China

Non Small Cell Lung Cancer

Recruiting NCT06183762☆ Save

A Real-World Study of Treatment Patterns and Effectiveness in MET Mutation-Positive Advanced Lung Cancer

— Observational China

Advanced Lung Cancer

Not yet recruiting NCT06590194☆ Save

PH009-1 in Patients With EGFR Mutation Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC)

Phase I / Phase II Interventional China

Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)