Recruiting NCT04996875
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Advanced Systemic Mastocytosis (AdvSM) · SM With an Associated Hematologic Neoplasm (SM-AHN) · Mast Cell Leukemia (MCL)
Hematology
3,640 trials in this section
Recruiting NCT07628634
Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors
Adenocarcinoma · Basal Cell Carcinoma · Squamous Cell Carcinoma
Recruiting NCT07295951
A Study of 14C-Bleximenib (Radiolabeled) in Participants With Acute Leukemia
Acute Lymphoblastic Leukemia · Acute Leukemias · Acute Myeloid Leukemia
Recruiting NCT07615686
tSCS in Children With Spina Bifida
Spina Bifida · Myelomeningocele
Recruiting NCT07061951
Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia
Recurrent Chronic Lymphocytic Leukemia · Recurrent Small Lymphocytic Lymphoma · Refractory Chronic Lymphocytic Leukemia
Not yet recruiting NCT07739849
Flow on FNA/Core Project- Faster Diagnosis for Lymphoma: Utilising Flow Cytometry on FNA Samples of Lymph Nodes to Diagnose Lymphoma in Hours, Not Days.
Cancer · Lymphoma
Recruiting NCT06287944
225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome
Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia · Myelodysplastic Syndrome
Recruiting NCT04811560
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Acute Leukemia
Recruiting NCT06285318
A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials
Relapsed/Refractory Multiple Myeloma (RRMM)
Not yet recruiting NCT07740174
Efficacy of Seated Exercise on Functional Capacity and Quality of Life in Patients With Leukemia During Chemotherapy Cycles
Leukemia
Recruiting NCT01804686
A Long-term Extension Study of PCI-32765 (Ibrutinib)
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma · Mantle Cell Lymphoma
Recruiting NCT07739654
Modified DHAP Versus Standard DHAP in Relapsed/Refractory Diffused Large B-cell Lymphoma.
DLBCL - Diffuse Large B Cell Lymphoma
Recruiting NCT06967610
Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).
Chronic Lymphocytic Leukemia · Small Lymphocytic Leukemia (SLL)
Recruiting NCT06207799
Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma
Multiple Myeloma · Post-transplant MRD-guided Maintenance Therapy · Pre-transplant Purging
Not yet recruiting NCT07137481
Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies
Hematological Malignancies
Recruiting NCT07652281
A Clinical Study of SHR-5421 in Patients With Multiple Myeloma
Multiple Myeloma
Not yet recruiting NCT07735546
A Phase 1 Study of UB-VV500 With Rapamycin in Relapsed/Refractory Multiple Myeloma
Multiple Myeloma in Relapse · Multiple Myeloma (MM)
Not yet recruiting NCT07737262
Prophylactic NAC to Improve Platelet Engraftment After Haploidentical Transplantation in Severe Aplastic Anemia Patients
Aplastic Anemia
Recruiting NCT03486873
Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)
Solid Tumors · Hematologic Malignancies
Not yet recruiting NCT07072585
Testing the Addition of Daratumumab to Chemotherapy for Treating Patients With Newly-Diagnosed T-Cell Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LL)
Stage II T Lymphoblastic Leukemia/Lymphoma · Stage III T Lymphoblastic Leukemia/Lymphoma · Stage IV T Lymphoblastic Leukemia/Lymphoma
Recruiting NCT04609046
Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma
Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System
Recruiting NCT07424833
A Study of APG-3288 in Relapsed/Refractory Blood Cancers
Relapsed/Refractory Hematological Malignancies · Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Leukemia (CLL/SLL · Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL; Including Richter Transformation)
Recruiting NCT07197307
Combining Loncastuximab Tesirine and Epcoritamab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)
Aggressive Diffuse Large B-cell Lymphoma · High-grade B-cell Lymphoma (HGBL) · Follicular Lymphoma (FL) Grade 3B
Recruiting NCT05327023
Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic Malignancies
Hematologic Neoplasms
Not yet recruiting NCT07735637
A Phase III, Multicentre Study to Evaluate Consolidation Treatment With AZD0120 Compared With ASCT, in Participants With Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible (DURGA-6).
Newly Diagnosed Multiple Myeloma (NDMM)
Not yet recruiting NCT07735533
A Phase 1/2 Study of UB-VV400 With Rapamycin in Relapsed/Refractory B-cell Malignancies
Lymphoma, B Cell · Lymphoma Non-Hodgkin · High Grade B Cell Lymphoma
Recruiting NCT06717347
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Diffuse Large B-Cell Lymphoma
Recruiting NCT06529731
Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation
Acute Myeloid Leukemia · Myelodysplastic Syndromes
Recruiting NCT07285044
The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
Amyloidosis · Basal Cell Carcinoma · Biliary Tract Carcinoma
Recruiting NCT07096778
Inobrodib, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma
Multiple Myeloma Refractory · Multiple Myeloma in Relapse
Not yet recruiting NCT07551583
Phase 2 Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHL
Hodgkin Lymphoma
Recruiting NCT07566364
Phase 2 Study Of Mosunetuzumab In Patients With Chronic Lymphocytic Leukemia With Positive MRD
Lymphocytic Leukemia
Recruiting NCT07548710
Study of SA+X in the Treatment of Newly Diagnosed AML
Acute Myeloid Leukemia
Not yet recruiting NCT07674823
Study Of KITE-753 in R/R B-Cell ALL
B-cell Acute Lymphoblastic Leukemia
Enrolling by invitation NCT04266093
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology Studies
Cervical Intraepithelial Neoplasia · Cervical Neoplasms · Oropharyngeal Neoplasms
Recruiting NCT05705531
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
Cardiovascular Disorder · Classic Hodgkin Lymphoma · Clonal Hematopoiesis
Recruiting NCT06500273
Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL
Large B-cell Lymphoma
Not yet recruiting NCT07737769
Arsenic Trioxide to Prevent Relapse in Patients Undergoing Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia or Myelodysplastic Syndrome
Acute Myeloid Leukemia · Myelodysplastic Syndrome
Recruiting NCT07609862
A Study of Rocbrutinib in Combination With Lacutoclax in Patients With B-Cell Malignancies
Mantle Cell Lymphoma (MCL) · Diffuse Large B-Cell Lymphoma (DLBCL) · Follicular Lymphoma ( FL)
Recruiting NCT05645718
Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia
Leukemia
Recruiting NCT06785818
Long-term Follow up Local Registry Study of Kymriah in South Korea
B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma
Recruiting NCT05110742
Phase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances
Hematological Malignancy
Recruiting NCT07609823
A Study of Lacutoclax (LP-108) in Patients With Relapsed/Refractory CLL/SLL
Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Recruiting NCT05365659
IKS03 in Patients With Advanced B Cell Non-Hodgkin Lymphomas
B-cell Non-Hodgkin Lymphoma · Diffuse Large B Cell Lymphoma · Follicular Lymphoma
Recruiting NCT05519085
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
Relapsed or Refractory Multiple Myeloma
Not yet recruiting NCT07459608
Efficacy and Safety of Lisaftoclax (APG-2575) Monotherapy in Patients With Mature B-cell Lymphoma
Indolent Lymphoma · WM · MZL
Recruiting NCT07397832
CRP Regimen in Treating Elderly Patients With Previously Untreated Double-Positive DLBCL
Diffuse Large B-Cell Lymphoma (DLBCL)
Recruiting NCT04293562
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Acute Myeloid Leukemia
Recruiting NCT06516679
Efficacy of Risk-Stratified Treatment in Newly Diagnosed Infant Leukemia
Leukemia, Lymphoid
Recruiting NCT03460977
A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
Metastatic Castration Resistant Prostate Cancer (mCRPC) · Small Cell Lung Cancer (SCLC) · Follicular Lymphoma (FL)
Not yet recruiting NCT07470489
Zanzalintinib Plus Cemiplimab for the Treatment of BRAF Wild-Type Anaplastic Thyroid Cancer
Anaplastic Thyroid Cancer
Recruiting NCT07695701
Cardiac Magnetic Resonance and Echocardiography Study With Acoramidis
Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM) · Amyloidosis · Amyloid Cardiomyopathy
Recruiting NCT06943872
A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma
Recruiting NCT05827549
Evaluation of Treatment Efficacy According to Risk Group in Relapsed Childhood Acute Lymphoblastic Leukemia
Acute Lymphoid Leukemia
Recruiting NCT05645107
A Study to Evaluate Efficacy, Safety, and PK of XEMBIFY®+Standard Medical Treatment (SMT) Compared to Placebo+SMT to Prevent Infections in Participants With HGG and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemia, Multiple Myeloma, and Non-Hodgkin Lymphoma
Hypogammaglobulinemia · Bacterial Infections · B-cell Chronic Lymphocytic Leukemia
Recruiting NCT07730515
Clinical Study of XNW5004 Combined With CHOP/CHOEP in the Treatment of Untreated Peripheral T-Cell Lymphoma
Non-hodgkin Lymphoma · Peripheral T-cell Lymphoma
Recruiting NCT06184009
Treatment of Newly Diagnosed High Risk Pediatric Acute Lymphoblastic Leukemia
Pediatric Acute Lymphoblastic Leukemia
Not yet recruiting NCT07732712
Isa-VRdlite for of Frail and/or Much Older Patients With High Risk Newly Diagnosed Multiple Myeloma Base on Circulating Plasma Cells
Multiple Myeloma
Recruiting NCT03779854
Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant
Acute Biphenotypic Leukemia · Acute Leukemia · Acute Leukemia of Ambiguous Lineage
Not yet recruiting NCT07734038
Venetoclax Plus Zanubrutinib for the Treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia · Small Lymphocytic Lymphoma
Recruiting NCT07015242
A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma
Lymphoma
Recruiting NCT04840602
Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma
Lymphoplasmacytic Lymphoma · Waldenstrom Macroglobulinemia
Not yet recruiting NCT07734285
Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy
Cardiac Amyloidosis · Left Ventricular Hypertrophy · Conduction Abnormality
Recruiting NCT06616636
A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)
Myelodysplastic Syndrome · Acute Myeloid Leukemia
Not yet recruiting NCT07733713
Hysteroscopy and CD138+ Plasma Cell Density in Chronic Endometritis
Chronic Endometritis
Recruiting NCT07507760
Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients
Acute Myeloid Leukemia With Gene Mutations
Recruiting NCT06099366
Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children
Lymphoblastic Leukemia in Children
Recruiting NCT06257394
Treatment of Pediatric Very High-risk Acute Lymphoblastic Leukemia in Korea
Acute Lymphoblastic Leukemia, Pediatric
Recruiting NCT07609940
Adult Outpatient Linvoseltamab With Tocilizumab Prophylaxis to Mitigate the Risk of Cytokine Release Syndrome (CRS)
Relapsed/Refractory Multiple Myeloma (RRMM)
Not yet recruiting NCT07735117
Mitoxantrone Hydrochloride Liposome, Cytarabine, G-CSF Plus Venetoclax vs. Azacitidine Plus Venetoclax for MDS-IB2 and Secondary/Elderly AML
Acute Myeloid Leukemia (AML) · Myelodysplastic Syndromes (MDS)
Not yet recruiting NCT07735208
Geriatric Assessment-Guided Treatment Selection in Older Adults With Acute Myeloid Leukemia
Acute Myeloid Leukemia
Recruiting NCT04588922
Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML
Hematologic Malignancies
Enrolling by invitation NCT06987058
RVU120 Rollover Study
Advanced Solid Tumors · Acute Myeloid Leukaemia (AML) · High-risk Myelodysplastic Syndrome
Recruiting NCT06465810
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Transthyretin Amyloidosis · ATTR-CM · ATTRv-PN
Recruiting NCT06150664
A Phase 1 of CTX-8371 in Patients With Advanced Malignancies
Non Small Cell Lung Cancer · Triple Negative Breast Cancer · Hodgkin Lymphoma
Recruiting NCT07586618
First-in-human Study of a New Treatment (4A10) for Patients With Relapsed or Hard-to-treat Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma, Focused on Safety and How the Drug Behaves in the Body and Early Signs of Effect.
Lymphoblastic Lymphoma · Acute Lymphoblastic Leukemia ALL
Not yet recruiting NCT07731789
Tafasitamab and Rituximab for the Treatment of Newly Diagnosed Follicular Lymphoma
Classic Follicular Lymphoma · Grade 1 Follicular Lymphoma · Grade 2 Follicular Lymphoma
Recruiting NCT01087333
Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment
Hairy Cell Leukemia (HCL) · Chronic Lymphocytic Leukemia (CLL) · Non-Hodgkins Lymphoma (NHL)
Enrolling by invitation NCT04093570
A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Acute Myeloid Leukemia · Chronic Myelomonocytic Leukemia · Myelodysplastic Syndromes
Recruiting NCT03258567
Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas
Epstein-Barr Virus Infections · Lymphoma · Lymphoproliferative Disorder
Recruiting NCT07485855
Influenza Vaccination Strategy for Patients With Hematologic Malignancy
Hematologic Neoplasms · Influenza · Immunogenicity
Recruiting NCT07020533
A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant
Accelerated Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive · Acute Lymphoblastic Leukemia · Acute Myeloid Leukemia
Recruiting NCT07691606
A Study of ARC-02 in B-cell NHL
B-cell Non Hodgkin Lymphoma
Recruiting NCT07335887
Sonrotoclax Plus Dexamethasone With or Without Daratumumab Regimen in Patients With t(11;14) Primary AL Amyloidosis
AL Amyloidosis (AL) · t(11;14) Positive
Recruiting NCT07272499
Orelabrutinib Plus Lisaftoclax and Rituximab in Untreated Mantle Cell Lymphoma With High-Risk Disease
Mantle Cell Lymphoma (MCL)
Recruiting NCT07191119
Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia
Survivor of Childhood Cancer · Insomnia · Acute Lymphoblastic Leukemia (ALL)
Recruiting NCT07398950
Prospective Evaluation of Artificial Intelligence-enabled Screening for Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
ATTR Amyloidosis With Cardiomyopathy · Heart Failure
Recruiting NCT07099391
A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma
Multiple Myeloma
Not yet recruiting NCT07717164
PRAISE-IR Versus CIBMTR Controls
ALL (Acute B-Lymphoblastic Leukemia) · AML (Acute Myeloid Leukemia) · MDS (Myelodysplastic Syndrome)
Not yet recruiting NCT07728188
A Study to Evaluate Adverse Events and Change in Disease Activity With Injected Etentamig Plus Oral Pomalidomide Versus Standard Therapies in Adults With Relapsed or Refractory Multiple Myeloma
Relapsed or Refractory Multiple Myeloma
Recruiting NCT04045470
A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma
Cutaneous T Cell Lymphoma · Peripheral T Cell Lymphoma
Recruiting NCT07549516
A Study on the Tolerability, Safety and Effectiveness of Asciminib in Patients With Philadelphia Chromosome-positive Chronic Myeloid Leukemia in the Chronic Phase in Germany
Leukemia, Chronic Myeloid
Recruiting NCT07007312
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Acute Myeloid Leukemia (AML)
Recruiting NCT07727694
Securing Access to Innovative Molecules in Oncology and Hematology for Children, Adolescents and Young Adults
Pediatric Cancer
Not yet recruiting NCT07621887
Digitalized Exercise Fit Tool Intervention for Adolescents With Blood Cancer
Hematologic Cancer · Leukaemia · Lymphoma
Recruiting NCT03816319
TAK-243 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndromes With Increased Blasts
Myelodysplastic Syndrome With Excess Blasts · Recurrent Acute Myeloid Leukemia · Recurrent Myelodysplastic Syndrome
Recruiting NCT07671209
Addressing Cancer Care Equity With Social Determinants of Health Screening and Early Intervention
Leukemia, Acute
Recruiting NCT06917911
Testing the Addition of Venetoclax or Gemtuzumab Ozogamicin (GO) to Usual Treatment Regimen (Cytarabine and Daunorubicin, "7+3") for Core Binding Factor Acute Myeloid Leukemia (CBF-AML) to Improve Response (A MYELOMATCH Treatment Trial)
Core Binding Factor Acute Myeloid Leukemia
Recruiting NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
B-cell Acute Lymphoblastic Leukemia · Diffuse Large B-cell Lymphoma · Burkitt Lymphoma
Recruiting NCT04898790
Improving Cognitive Function in Older Adults Undergoing Stem Cell Transplant
Leukemia · Lymphoma · Multiple Myeloma