Recruiting NCT06243393
Sacituzumab Govitecan in Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
GI & liver
8,202 trials in this section
Not yet recruiting NCT06493448
Prospective Observational Cohort Study
Gastric Cancer · Liver Metastases
Not yet recruiting NCT06492941
A Study of Docetaxel for Injection (Albumin Bound) in Patients With Advanced Pancreatic Cancer
Advanced Pancreatic Cancer
Recruiting NCT05462236
MNK Inhibitor AUM001 in Combination With Either Pembrolizumab or Irinotecan to Treat Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Recruiting NCT06491472
Ivonescimab(AK112/SMT112) in Combination With Stereotactic Body Radiation Therapy and Chemotherapy in Patients With Pancreatic Cancer
Pancreatic Cancer
Recruiting NCT06492408
Neoadjuvant Intra-tumor Double Immunotherapy for Hepatocellular Carcinoma.
Hepatic Cancer · Surgery
Not yet recruiting NCT06492317
RC48 Plus AK104 as First-line Treatment for HER2-overexpressing Advanced Gastric Cancer
HER2-positive Gastric Cancer
Recruiting NCT06124456
Vigorous- Versus Moderate-intensity Exercise to Reduce Liver Fat in Adults With Obesity and NAFLD
Obesity · NAFLD
Not yet recruiting NCT06491134
Liposomal Irinotecan With Cisplatin and Concurrent Radiotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Not yet recruiting NCT06490198
Phase 2 Study: OBI-833/OBI-821 Maintenance for Globo H+ Advanced Biliary Tract Cancer After Gemcitabine/Cisplatin
Cholangiocarcinoma · Chemotherapy Effect · Immunotherapy
Recruiting NCT06313567
Metronomic Capecitabine in Stage III Gastric Cancer
Gastric Cancer
Recruiting NCT06487663
TACE Combined With Immune Checkpoint Inhibitors for Liver Malignant Tumors
Hepatocellular Carcinoma Non-resectable · Cholangiocarcinoma Non-resectable · Liver Metastases
Recruiting NCT06466902
Evaluation of Intra-operative Photographs for the Assessment of a Proper Lymphadenectomy in Minimally-invasive Gastrectomies for Gastric Cancer (PhotoNodes)
Gastric Cancer · Gastric Adenocarcinoma · Lymphadenectomy
Recruiting NCT06487429
Short Course Radiotherapy With Sequential Disitamab Vedotin Combined With S-1 and Sintilimab as Whole Course Neoadjuvant Therapy for HER2 Expressed Locally Progressive Gastric Cancer
Gastric Cancer
Enrolling by invitation NCT06487312
Clinical Trial to Evaluate the Effectiveness and Safety of a Remote Automated Ultrasound Diagnostic System for Automated Ultrasound Examinations: a Prospective, Multicenter Study
Ultrasound · Thyroid · Carotid Artery
Not yet recruiting NCT06487702
A Phase lb/lI Clinical Study in Advanced or Metastatic Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Recruiting NCT06485271
A Real-world Study of Camrelizumab Alone or in Combination With Apatinib/Chemotherapy for Advanced Gastric Cancer
Gastric Cancer · RWS · PD-1 Immunotherapy
Not yet recruiting NCT06484153
Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Advanced or Metastatic pMMR/MSS Colorectal Carcinoma
To Evaluate the Efficacy of Fruquintinib and Pirfenidone in Combination With Anti-PD-1 Antibody in Colorectal Carcinoma · To Evaluate Whether Pirfenidone Can Reshape the Tumor Microenvironment in Colorectal Cancer · Combination of Fruquintinib and Anti-PD-1 Antibody Was Reported to Improve Patient Prognosis in Colorectal Cancer
Recruiting NCT06298968
Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma
Recruiting NCT06339060
An Organ Preservation Strategies After Chemoradiotherapy Combined With Immunotherapy for Esophageal Cancer (PALACE3).
Esophageal Cancer
Recruiting NCT04520737
Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases
Prehabilitation · Neoadjuvant Therapy · Liver Metastases
Recruiting NCT06385730
Neoadjuvant PD-1 Blockade for Elderly Esophageal Squamous Cell Carcinoma (BLESS)
Esophageal Cancer
Recruiting NCT06482801
Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT
Liver Cancer · Antibody
Not yet recruiting NCT06469060
Neoadjuvant Immunochemotherapy for Adenocarcinoma of the Esophagogastric Junction
Esophageal Cancer
Recruiting NCT06482788
Perioperative Treatment of Resectable Adenocarcinoma of Esophagogastric Junction by Immunotherapy (Adebrelimab) Combined With Chemotherapy (XELOX): a Prospective, Single-center, Feasibility Study
Esophagogastric Junction Adenocarcinoma
Recruiting NCT06454448
Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancer
Adebrelimab (SHR-1316) · Decitabine · Metastatic Pancreatic Cancer
Recruiting NCT06314646
Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients
Rectal Cancer · Surgery
Not yet recruiting NCT06478264
A Study of Adebrelimab Combined With Chemoradiotherapy in the Treatment of Esophageal Small Cell Carcinoma
Esophageal Small Cell Carcinoma
Recruiting NCT06196697
AK104 in Combination With AK112 Plus Chemotherapy(SOX/XELOX) as First-line Treatment for Advanced G/GEJ Cancer
Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma
Recruiting NCT06477991
The Efficacy of Watch and Wait Strategy or Surgery After Neoadjuvant Immunotherapy for Locally Advanced Colorectal Cancer With dMMR/MSI-H Guided by MRD Dynamic Monitoring: A Single-center, Open-label, Prospective, Phase II Clinical Trial.
Clinical Complete Response Rate With Negative MRD
Recruiting NCT06478927
Backline Treatment of Advanced Hepatocellular Carcinoma With Palbociclib
Hepatocellular Carcinoma
Recruiting NCT03949231
Infusion of PD1/PDL1/CTLA4 Inhibitors Via Hepatic Arterial for Immunotherapy of Hepatocellular Carcinoma
Liver Cancer
Recruiting NCT06385418
Fluorouracil Treatment Via Colon for Colorectal Cancer
Colorectal Cancer
Recruiting NCT03596476
Diagnostic Yield of Post PRandial Esophageal High Resolution Impedance Manometry in Patients With Gastro-Esophageal Reflux Disease Symptoms Resistant to Proton Pump Inhibitor Therapy
Gastro-esophageal Reflux Disease
Recruiting NCT04803318
Trametinib Combined With Everolimus and Lenvatinib for Recurrent/Refractory Advanced Solid Tumors
Solid Tumor, Adult · Hepatocellular Carcinoma
Recruiting NCT06359275
PD-1 Combined With Chemotherapy and PULSAR in LAPC and Local Recurrence Patients
Pancreatic Cancer
Not yet recruiting NCT06470178
A Real-World Study of Neoadjuvant/Conversion Therapy for Colorectal Cancer With Chemotherapy And Anti-Angiogenic Targeted Agents
Colorectal Cancer
Recruiting NCT06390878
Nationwide Research on the Rewilding of Kindergarten Yards
Microbial Colonization · Atopic Dermatitis · Asthma in Children
Not yet recruiting NCT05498766
Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients
Gastric Cancer
Recruiting NCT06341335
A Study of AK104/Placebo Plus AK109/Placebo And Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma
Gastric and Gastroesophageal Junction Adenocarcinoma
Recruiting NCT06470256
Palliative Hepatectomy Combined With Targeted Therapy and Immunotherapy for Advanced Hepatocellular Carcinoma
Advanced Hepatocellular Carcinoma
Recruiting NCT06161207
3D-4K-ICG Laparoscopic Gastrectomy for Gastric Cancer
Gastric Cancer · Surgery
Not yet recruiting NCT06468670
Short-course Radiotherapy Combined With Sintilimab for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Not yet recruiting NCT06468488
Impact of Drainless Donor Abdominal Site in Deep Inferior Epigastric Perforator (DIEP) Flap on Complications and Duration of Hospital Stay.
Breast Reconstruction
Not yet recruiting NCT06468644
Phase II Study of Different Doses of Radiotherapy Combined With Sintilimab in the Treatment of Locally Advanced Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Recruiting NCT06469593
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
Diabetes Mellitus, Type 1
Not yet recruiting NCT06468969
Enhanced vs. Routine Follow-Up After Total Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial
Gastric Cancer · Total Gastrectomy · Postoperative Care
Enrolling by invitation NCT05877456
Validation of the Global Polypectomy Assessment Tool (GPAT)
Colorectal Adenoma · Colorectal Polyp · Colo-rectal Cancer
Recruiting NCT06466707
Collection of Microbiome Samples of Healthy Western Donors for Fundamental and Functional Microbiome Research
Microbial Colonization
Recruiting NCT06147635
Prophylactic Tributyrin Supplementation in Acute Pancreatitis
Acute Pancreatitis
Recruiting NCT04340986
Cohort of Patients With Hepatocellular Carcinoma or Cholangiocarcinoma
Cholangiocarcinoma · Hepatocellular Carcinoma
Recruiting NCT02864485
Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases
Colorectal Cancer · Liver Metastases
Not yet recruiting NCT06464601
A Real-World Study of Neoadjuvant/Conversion Therapy for Locally Advanced or Metastatic Gastric Cancer
Gastric Cancer
Not yet recruiting NCT06463548
Irinotecan Hydrochloride Liposome Combined With Capecitabine and Lenvatinib in Patients With Biliary Tract Carcinoma
Biliary Tract Carcinoma
Recruiting NCT06463834
A Study of Sintilimab Combined With Chemotherapy for Neoadjuvant Treatment of Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma
Recruiting NCT06462053
Short-course Radiotherapy Combined With CAPOX and PD-1 Antibody Versus Long-course Chemoradiotherapy Combined With CAPOX for Early Low-lying Rectal Cancer
Early Low Rectal Cancer
Recruiting NCT05701241
Continuing Somatostatin Analogues Upon Progression in Neuroendocrine Tumour pAtients
Gastroenteropancreatic Neuroendocrine Tumor
Recruiting NCT04050345
Tracking Mutations in Cell Free Tumour DNA to Predict Relapse in Early Colorectal Cancer
Colorectal Cancer
Recruiting NCT06084897
Radiotherapy in Patients With Metastatic Esophageal Cancer Responding to PD-1 Inhibitor Plus Chemotherapy
Esophageal Neoplasm Metastatic · Esophageal Cancer Stage IVb
Not yet recruiting NCT06460896
Analysis of the Influence of Gastric By-Pass on the Pharmacokinetics of Common Drugs
Bypass Bariatric Surgery
Recruiting NCT05257746
Perioperative and Postoperative Evaluation of Rectal and Urogenital Function in Patients Undergoing Rectal Resection
Rectal Surgery
Recruiting NCT06253650
Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease
Gastric Cancer · HER2-positive Gastric Cancer
Recruiting NCT06455124
Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)
Rectal Cancer
Recruiting NCT04678583
Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer
Colorectal Liver Metastasis
Not yet recruiting NCT06454435
Conversion Therapy of Sintilimab in Combination With Fruquintinib and Chemotherapy Versus Sintilimab and Chemotherpay in Stage IV Gastric Cancer
Gastric Cancer · Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma
Not yet recruiting NCT06455501
FOAM: Functional Outcome After Ventral Mesh Rectopexy
Rectal Prolapse
Recruiting NCT06451393
Predicting Gastric Cancer Response to Chemo With Multimodal AI Model
Gastric Cancer · Chemotherapy Effect
Recruiting NCT06451211
Neoadjuvant Immunotherapy Plus Chemotherapy in Borrmann Type 4 and Large Type 3 Gastric Cancer
Stomach Neoplasms · Gastric Cancer · Linitis Plastica of Stomach
Recruiting NCT06452966
The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients
Organ Failure, Multiple · Indigestion · Delayed Gastric Emptying
Recruiting NCT06449833
Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD
Type2 Diabetes Mellitus · Nonalcoholic Fatty Liver Disease
Recruiting NCT06449937
Local Liver Treatment for Multi-organ Colorectal Cancer Metastases
Metastatic Colorectal Carcinoma · Multi-organ Metastatic Colorectal Cancer · Metastatic Malignant Neoplasm in the Liver
Not yet recruiting NCT06450574
Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study)
Rectal Cancer Stage I
Not yet recruiting NCT06449846
Compare the Accuracy of ctDNA-MRD and MVI Result in Predicting Postoperative Recurrence of Hepatocellular Carcinoma
Hepatocellular Carcinoma Resectable · Surgery · Recurrence
Recruiting NCT06018896
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
Metastatic Pancreatic Cancer · Terminal Cancer
Recruiting NCT04891016
Toripalimab Plus FLOT in Locally Advanced Gastric Cancer
Chemotherapy · Immune Checkpoint Inhibitor · Locally Advanced Gastric Carcinoma
Enrolling by invitation NCT05287737
Clinical Outcome After Total Pancreatectomy With Islet Autotransplantation
Islets of Langerhans Transplantation · Pancreatitis, Chronic · Diabetes Mellitus
Recruiting NCT06446050
Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer
Advanced Colorectal Cancer
Not yet recruiting NCT06446908
Acceptability and Feasibility of a New Approach to Engage Patients With Steatotic Liver Disease in Physical Activity
Liver Steatosis · MASH · MASLD
Enrolling by invitation NCT06443996
Association of Sleep Quality and Mental Status With Early Recurrence and Prognosis of Colorectal Cancer
Colorectal Cancer · Sleep Quality · Mental Status Change
Not yet recruiting NCT06443671
Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer
Rectal Cancer
Recruiting NCT05304234
Liver Cancer Disparities in American Indian and Alaska Native Persons
Hepatocellular Carcinoma · Cirrhosis, Liver · Hepatitis B
Recruiting NCT06440902
Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA
Colorectal Cancer Metastatic
Recruiting NCT05309863
Comparison Between the Efficacy of Residential and Ambulatory Weight Loss Programs for Pediatric Non-alcoholic Fatty Liver Disease
Pediatric Non-alcoholic Fatty Liver Disease
Not yet recruiting NCT06275997
GAIN Project: Gastric Cancer and Artificial Intelligence
Gastric Cancer
Recruiting NCT03349762
Huaier Granules for Prevention of Recurrence and Metastasis of Colorectal Cancer Patients Following Radical Surgery
Colorectal Cancer
Not yet recruiting NCT06439550
Adjuvant Treatment With Serplulimab，Trastuzumab and SOX in the HER-2 Positive GC/GEJC
HER2-positive Gastric Cancer
Not yet recruiting NCT06435689
Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers
Colon Cancer · Peritoneal Carcinoma
Not yet recruiting NCT06364462
Precise Evaluation Criteria for Histological Regression of NASH Fibrosis
NASH · Liver Fibrosis
Recruiting NCT06415669
A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma
Gastric/Gastroesophageal Junction Adenocarcinoma
Not yet recruiting NCT06432075
Neoantigen Reactive T Cells c for Chinese Patients With Advanced Gastric Cancer
Advanced Gastric Cancer
Recruiting NCT06429839
Nimotuzumab Concurrent With Chemoradiotherapy for Esophageal Cancer Patients
Esophageal Cancer · Nimotuzumab · Chemoradiotherapy
Not yet recruiting NCT06405958
Gut Microbiome Analysis in Organ Transplant Recipient
Microbial Colonization
Recruiting NCT05911217
A Study to Evaluate the Efficacy and Safety of CT041 After Adjuvant Chemotherapy for Pancreatic Cancer
Pancreatic Cancer
Not yet recruiting NCT06426654
Sintilimab Combined With LDRT for Neoadjuvant Treatment of Locally Advanced dMMR/MSI-H Gastric Cancer
Gastric Cancer
Recruiting NCT06427460
Central-boost Ablative Radiation Therapy for Solid Tumors (CBART)
Pancreatic Cancer
Not yet recruiting NCT06426797
Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell Carcinoma
Locally Advanced Esophageal Squamous Cell Carcinoma
Recruiting NCT05536089
ctDNA Methylation Application in Postoperative Relapse and Adjuvant Chemotherapy Efficacy Evaluation
Cancer Colorectal
Recruiting NCT06420700
Ablation Registry (Combined Gastric Mucosal Ablation With Endoscopic Sleeve Gastroplasty for Weight Loss)
Obesity
Recruiting NCT02920554
The Effect in Wedge Resection and IVb/V Resection of the Liver for Gallbladder Cancer
Gallbladder Cancer
Recruiting NCT06204835
ITGA6 Targeting NIR-II Fluorescence Image Guided Surgery
Hepatocellular Carcinoma