Recruiting NCT06004245
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
Advanced Solid Tumors · Colorectal Cancer
GI & liver
8,202 trials in this section
Not yet recruiting NCT07714538
Breath Research Narrow Validation for Gastrointestinal Cancer Detection
Oesophageal Squamous Cell Carcinoma · Oesophageal Adenocarcinoma · Gastric Adenocarcinoma
Recruiting NCT07673887
A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer
Gastric Adenocarcinoma · Gastroesophageal Junction (GEJ) Adenocarcinoma
Recruiting NCT06796114
Identification of Innovative Biomarkers to Predict Outcomes in Hepatocellular Carcinoma Treated With Tremelimumab and Durvalumab
Hepatocellular Carcinoma
Recruiting NCT06943612
Colorectal Resections in Patients With Retroperitoneal Sarcoma
Sarcoma, Soft Tissue · Retroperitoneal Sarcoma
Recruiting NCT06320717
AI Derived Biomarker to Select Neoadjuvant Treatment for Borderline Resectable Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Recruiting NCT06880770
Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
Severe Hypertriglyceridemia
Not yet recruiting NCT07722754
Bevacizumab, Sintilimab, Cetuximab and Irinotecan in Refractory RAS Wild-type Metastatic Colorectal Cancer: BOND-4 Trial
Colorectal Neoplasms Malignant · Neoplasm, Metastatic
Not yet recruiting NCT07634939
Liver Micro Flow - MRI
Liver Diseases
Not yet recruiting NCT07692555
Development and Validation of a Colorectal Cancer Diagnostic Model
Colorectal Cancer · Advanced Neoplasia · Prediction Models
Recruiting NCT07133750
PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer
CRC (Colorectal Cancer)
Recruiting NCT06729632
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
Noise Exposure · Noise-induced Hearing Loss · Noise; Adverse Effect
Recruiting NCT07521852
A Phase IIa, Single-arm, Open-label Clinical Study to Evaluate the Efficacy, Safety and PK of CVM-1118 in Combination With Sintilimab and TACE in Participants With Incurable/Non-metastatic HCC
HCC - Hepatocellular Carcinoma
Not yet recruiting NCT07723781
Structured Case-Finding for Pancreatic Ductal Adenocarcinoma in Swiss Primary Care: A Feasibility Study
Pancreatic Adenocarcinoma (Ductal Adenocarcinoma) · Early Detection of Cancer
Recruiting NCT07723937
GelPOINT® Path-Assisted Endoscopic Removal of Colon and Rectal Polyps: A Feasibility and Safety Study
Polyp Colorectal · Rectal Adenoma · Adenoma Colon Polyp
Recruiting NCT07587866
Panuri Performance Study
Pancreatic Ductal Adenocarcinoma (PDAC)
Recruiting NCT07269301
A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function
Hepatic Impairment · Healthy
Not yet recruiting NCT07722494
IBI363 Combined With Bevacizumab for Advanced Colorectal Cancer
Colorectal Cancer
Recruiting NCT06545942
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
Advanced Solid Tumor · Metastatic Solid Tumor · Prostate Cancer
Not yet recruiting NCT07674771
Response With Interim PSMA PET in Metastatic Castration-sensitive Prostate Cancer for Optimization of Adaptive Metastasis-directed Radiotherapy Delivery
Prostate Cancer · Castration Sensitive Prostate Cancer · Metastatic Prostate Cancer
Recruiting NCT06974110
Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors
Advanced Solid Tumor · Metastatic Solid Tumor · Endometrial Cancer
Not yet recruiting NCT07557303
Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study
Delivery of Health Care · Genetic Testing · Humans
Recruiting NCT06755632
Screening of Patients With Hepatic Fibrosis or Cirrhosis B and C
Liver Pathology
Recruiting NCT07377487
TheraSphere Japan Pre-Market Study
Liver Neoplasms
Not yet recruiting NCT07723196
Effect of a Low AGE Diet on Liver Function in Adults With Fatty Liver.
MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Recruiting NCT06967571
Reconstruction With a Lawrence-Hunt Jejunal Pouch After Total Gastrectomy
Total Gastrectomy · Gastric Cancer
Recruiting NCT05376592
Assoc. of Genomic Polymorphisms With Cancer Cachexia in Subjects With Panc Adenocarcinoma
Pancreas Adenocarcinoma · Cachexia
Recruiting NCT07176715
Same-Day Colectomy: is it Safe for Patients?
Colorectal · Colectomy · Colectomy Left/Right/Total Under Laparotomy
Not yet recruiting NCT07183046
Implementation Intention Planning Guide for FIT Colon Cancer Screening
Fecal Immunochemical Test · Colorectal Cancer Screening
Recruiting NCT06375278
Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation
Cochlear Implants · Cochlear Implantation · Hearing Loss
Recruiting NCT07500298
Phase 1 Study Of SAR445877 In Combination With FOLFOX6 And Bevacizumab As First-Line Treatment For Microsatellite Stable Metastatic Colorectal Cancer
Phase 1 · SAR445877 · FOlfox6
Recruiting NCT07147231
Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer
Metastatic Colorectal Adenocarcinoma · Refractory Colorectal Adenocarcinoma · Stage III Colorectal Cancer AJCC v8
Recruiting NCT07721181
Radiotherapy Dose Escalation for Non-operative Management of Unresectable Locally Recurrent Rectal Cancer (STEP-UP)
Locally Recurrent Rectal Cancer
Recruiting NCT07718828
Laparoscopic Nissen Versus Toupet Fundoplication for Hiatal Hernia.
Hiatal Hernia, Paraesophageal · Hiatal Hernia Large · Hiatal Hernia With Gastroesophageal Reflux Disease
Not yet recruiting NCT07721103
Early Response-guided Sequential Radiotherapy After Chemoimmunotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma
Esophageal Squamous Cell Carcinoma (ESCC)
Not yet recruiting NCT06893276
e-Health Psychosocial Stress and Symptom Management (ePSMI) for Pancreatic Cancer Patients
Pancreatic Cancer
Recruiting NCT07222800
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
Intestinal Neoplasms · Gastrointestinal Neoplasms · Digestive System Neoplasms
Not yet recruiting NCT07648394
Research on the Efficacy and Mechanism of Shouhui Tongbian Capsules in Treating Postoperative Constipation of Benign Anal and Rectal Diseases Based on Gut Microbiota Analysis
Intestinal Flora · Anorectal Diseases · Surgery
Recruiting NCT07046819
Tirzepatide in MetALD
Metabolic Alcohol-associated Liver Disease · Alcohol Use Disorder
Not yet recruiting NCT07714850
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
Acute Pancreatitis (AP)
Recruiting NCT07076043
Multi-product PrEP Delivery to Young Women Seeking Reproductive Health Services and Coverage of HIV Prevention
Hiv
Recruiting NCT06192797
Combined HAIC, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma
Cholangiocarcinoma Non-resectable
Recruiting NCT04272515
Molecular Characterization for Understanding Biliary Atresia
Biliary Atresia
Recruiting NCT04970056
Pancreatic Cancer Early Detection Consortium
Pancreas Cancer · Pancreas Cyst · Pancreatic Ductal Adenocarcinoma
Recruiting NCT07221357
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Untreated, Unresectable, or Metastatic Colorectal Cancer
Not yet recruiting NCT07719426
Characterization of Colorectal Dysplasic Lesions and Stratification of Their Evolving Risk in Inflammatory Bowel Disease Patients: a Prospective, Observational and Multicenter Study
Crohn Disease (CD) · Colitis Ulcerative
Recruiting NCT07318805
A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors
Advanced Breast Cancer · Metastatic Breast Cancer (HR+/ HER2-) · Colorectal Cancer
Recruiting NCT07718490
Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer
Metastatic Colorectal Cancer
Not yet recruiting NCT07719673
Enteral Nutrition and Colonization Resistance Through Microbiota Modulation in Critically Ill Patients
Bacterial Colonization · Multidrug Resistant Organisms · Critical Illness
Recruiting NCT05253651
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
Colorectal Neoplasms
Not yet recruiting NCT07720505
COLOFLOW: Laser Speckle Contrast Imaging Versus Near-infrared Fluorescence Imaging With Indocyanine Green
Leakage, Anastomotic · Colon Cancer · Colon Anastomosis
Recruiting NCT06327308
Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant.
Cirrhosis · Registered on Transplant List
Recruiting NCT06834126
Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial
Locally Advanced Rectal Adenocarcinoma · Stage II Rectal Cancer AJCC v8 · Stage III Rectal Cancer AJCC v8
Recruiting NCT07227012
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
Carcinoma, Hepatocellular · Hepatocellular Cancer · Hepatocellular Carcinoma
Recruiting NCT07554521
A Study to Evaluate Efficacy and Safety of Tislelizumab Plus Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Adenocarcinoma and Esophageal Squamous Cell Carcinoma in Racial and Ethnic Minority Patients in the United States
Advanced Unresectable Gastric Adenocarcinoma · Esophageal Squamous Cell Carcinoma · Advanced Gastroesophageal Adenocarcinoma
Recruiting NCT06130826
Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer
Breast Carcinoma · Colorectal Carcinoma
Recruiting NCT07216456
Vaginal Dilator Therapy After Pelvic Radiation
Pelvic Radiotherapy · Vaginal Stenosis · Pelvic Cancer
Recruiting NCT05856591
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
Food Insecurity · Hypertension · Nutrition
Not yet recruiting NCT07707674
Phase I Open-Label Randomized Multicenter Study of XNW28012 Monotherapy in Metastatic Pancreatic Cancer
Metastatic Pancreatic Cancer
Recruiting NCT05177393
Treatment Outcomes of Esophageal Cancer
Esophageal Cancer
Recruiting NCT07720232
Bacillus Subtilis and Enterococcus Faecium Probiotic Plus Lipid-Lowering Therapy for Hypertriglyceridemic Acute Pancreatitis: A Prospective RCT
Hypertriglyceridemic Acute Pancreatitis · Acute Pancreatitis, Hypertriglyceridemia-induced · Hyperlipidemia
Enrolling by invitation NCT07441369
Abemaciclib Combined With FOLFOX/FOLFIRI Regimen in Patients With Advanced Colorectal Liver Metastases Cancer
Liver Metastases From Colorectal Cancer (mCRC)
Recruiting NCT04329494
PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer
Clinical Stage IV Gastric Cancer AJCC v8 · Clinical Stage IVA Gastric Cancer AJCC v8 · Clinical Stage IVB Gastric Cancer AJCC v8
Recruiting NCT03884075
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Non-Alcoholic Steatohepatitis · Non-Alcoholic Fatty Liver Disease
Recruiting NCT03334708
A Study of Blood Based Biomarkers for Pancreas Adenocarcinoma
Pancreatic Cancer · Pancreatic Diseases · Pancreatitis
Recruiting NCT06967701
Building and Sustaining Exercise Habits for Adults With Type 1 Diabetes
Type 1 Diabetes (T1D) · Latent Autoimmune Diabetes in Adult (LADA) · Pancreatitis
Recruiting NCT06847542
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
Neovascular Age-related Macular Degeneration
Not yet recruiting NCT07716995
Association Between Metabolic Associated Fatty Liver Disease and Obstructive Sleep Apnea
Obstructive Sleep Apnea · Metabolic Dysfunction-Associated Steatotic Liver Disease
Not yet recruiting NCT07716423
Remote Versus On-Site Robotic Surgery for Hepatobiliary and Pancreatic Procedures
Hepatobiliary and Pancreatic Diseases
Recruiting NCT05586776
Decolonization to Reduce After-Surgery Events of Surgical Site Infection
Surgical Site Infection
Recruiting NCT04174079
Study on Adjuvant Chemotherapy After Total Two-field Lymph Node Dissection of Thoracic Esophageal Squamous Cell Carcinoma
Thoracic Esophageal Squamous Cell Carcinoma
Not yet recruiting NCT07697690
Thoracic Epidural Analgesia for Acute Pancreatitis With Early Organ Dysfunction
Organ Dysfunction · Organ Support · Acute Pancreatitis (AP)
Not yet recruiting NCT07716670
Development and Prospective Validation of an AI-Based Diagnostic Model for Hepato-Pancreato-Biliary Diseases
Hepatic Disease · Biliary Disease · Pancreas Disease
Recruiting NCT02361320
Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer
Pancreatic Cancer
Not yet recruiting NCT07716384
Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness
Liver Fibrosis · Liver Cirrhosis · NAFLD (Nonalcoholic Fatty Liver Disease)
Recruiting NCT06801899
ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer
Pancreatic Cancer
Recruiting NCT07646613
Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients
Migraine
Recruiting NCT07291180
A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis
Appendiceal Cancer · Colorectal Adenocarcinoma · Peritoneal Metastases
Not yet recruiting NCT07715240
The HANAROSTENT® Multi-Hole™ Biliary Stent is Indicated for Use in the Palliative Treatment of Biliary Strictures Produced by Malignant Neoplasms and the Study is to Demonstrate Clinical Safety and Performance of the Multi-Hole™ Stent for the Palliative Treatment of Malignant Biliary Obstruction.
Biliary Strictures Caused by Malignant Neoplasms
Recruiting NCT06687603
Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms
Barrett Esophagus · Gastroesophageal Reflux · Esophageal Adenocarcinoma
Recruiting NCT07657897
The Impact of Anaesthesia and Sedation on Inflammation and NETosis in Hepatocellular Carcinoma Ablation
Hepato Cellular Carcinoma (HCC) · Sedation and Analgesia · Ablation Techniques
Not yet recruiting NCT07716449
QLS31905 in Combination With CAPOX Versus Sintilimab in Combination With CAPOX as First-line Treatment in Patients With GC/GEJ
Gastric or Gastroesophageal Junction Adenocarcinoma
Recruiting NCT07282912
Trial Comparing Standard of Care Therapy With and Without Sequential Cytoreductive Intervention for Patients With Metastatic Foregut Adenocarcinoma and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid (ctDNA) Levels
Foregut Adenocarcinoma · Esophageal Adenocarcinoma · Gastroesophageal Adenocarcinoma
Not yet recruiting NCT07716345
Inter-Individual Tumor Heterogeneity on 3D-MRE for Predicting Response to Conversion Therapy in Liver Cancer
Hepato Cellular Carcinoma · Intrahepatic Bile Duct Carcinoma · Metastatic Hepatocellular Carcinoma
Recruiting NCT05835505
Detoxification of the Liver In PSC (Dolphin)
Primary Sclerosing Cholangitis
Recruiting NCT07491445
Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC
Recruiting NCT07213609
A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
Neoplasms, Colorectal · Neoplasms
Not yet recruiting NCT07714447
Efficacy and Safety of Tunlametinib Combination Therapy in the Treatment of Second-line and Above Metastatic Colorectal Cancer
CRC (Colorectal Cancer) · BRAF
Recruiting NCT07685353
Influence of Donor and Recipient Genetic Polymorphisms on Graft Steatosis After Liver Transplant
Chronic Liver Disease and Cirrhosis
Recruiting NCT07222657
Liquid Nitrogen Spray Cryotherapy Prior to Neoadjuvant Systemic Therapy in Esophageal Adenocarcinoma
Esophageal Adenocarcinoma · Esophageal Cancer
Recruiting NCT07219459
Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure
Unresectable or Metastatic Hepatocellular Carcinoma · Child-Pugh A Hepatocellular Carcinoma · Failure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
Not yet recruiting NCT07716111
Neoadjuvant SHR-A1811 and SHR-A1701 ± Pertuzumab for Potentially Immunotherapy-Sensitive GC or GEJ Adenocarcinoma
Gastric or Gastroesophageal Junction Adenocarcinoma
Recruiting NCT07656181
International Delphi Study to Develop Standardized Quality Criteria and a Rating Tool for Liver CEUS Image Quality Assessment
Contrast Enhanced Ultrasound · Ultrasonic Diagnosis · Liver
Recruiting NCT07106359
Initial Testing of a Behavioral Intervention About Genetic Services for Families at Risk of Lynch Syndrome
Cascade Testing · Lynch Syndrome · Decision Making
Recruiting NCT05492136
Unravelling the Impact of Radiofrecuency in Liver Surgery: the Key to Decrease Local Recurrence?
Liver Cancer · Cancer, Treatment-Related
Not yet recruiting NCT07693751
A Study Testing SOT109 for the First Time in Patients, to Assess How Safe SOT109 is, How Well it Works, and How the Body Handles it in Patients With Advanced Colorectal Cancer That Can Not be Removed by Surgery or is Metastatic
Colorectal Cancer (Locally Advanced or Metastatic)
Not yet recruiting NCT07717502
Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)
Nulliparous Women Who Scheduled for Labor Induction · Pregnancy
Not yet recruiting NCT07718126
Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME)
Metabolic Dysfunction-Associated Steatohepatitis · Hepatic Steatosis · Living Liver Donors
Recruiting NCT07683065
A Study to Estimate Secukinumab Retention Rate in Psoriasis Patients With MASLD
Plaque Psoriasis · Metabolic Dysfunction-Associated Steatotic Liver Disease
Recruiting NCT04751435
Developing New Educational Materials About Genetic Testing for a Diverse Group of Cancer Patients
Educational Materials for Genetic Testing · Breast Cancer · Ovarian Cancer