Recruiting NCT07673900
Semaglutide Delivered Epi-Intradermally by Microarray Patch (VX-201) Versus Subcutaneous Administration in Healthy Overweight and Obese Participants
Overweight and/or Obesity
GI & liver
8,202 trials in this section
Recruiting NCT07580456
AI for Gastric POCUS ( Point-of-care Ultrasound)
Point-of-care Ultrasound
Not yet recruiting NCT07669727
A Post Approval Study to Evaluate Safety and Effectiveness of Multicompartmental Dosimetry Planning.
Hepatocellular Carcinoma (HCC)
Not yet recruiting NCT07739914
Everolimus bAsed caLcineurin inhibiTor frEe immunosuppRession oNe Year AfTer lIver transplantatiON (ALTERNATION)
Liver Allograft · Liver Diseases · Liver Transplantation
Not yet recruiting NCT03654079
Patient Centered Simulation For Labor and Delivery
Pregnancy Related
Recruiting NCT07419841
A Phase 1 Study of the Safety and Tolerability of CTX-10726
Gastroesophageal Cancer (GC) · Hepatocellular Carcinoma (HCC) · Endometrial Cancer
Recruiting NCT07335601
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
MASH - Metabolic Dysfunction-Associated Steatohepatitis
Recruiting NCT07135050
Phase 1/2 Study of MZ-1866, an AAV-9 Gene Therapy Delivered by Intracerebroventricular Injection to Participants With Pitt Hopkins Syndrome
Pitt Hopkins Syndrome
Recruiting NCT03683251
Extension Study for the Port Delivery System With Ranibizumab (Portal)
Neovascular Age-Related Macular Degeneration
Not yet recruiting NCT07570537
TubeClear System Evaluation in Pediatric Patients
Clogged Enteral Access Devices · Occluded Enteral Access Devices · Enteral Nutrition
Recruiting NCT07448077
Short-course Radiotherapy in TNT Combined With Enlonstobart for pMMR LARC
Efficacy and Safety of Short-course Radiotherapy in Total Neoadjuvant Therapy Combined With Enlonstobart for pMMR Locally Advanced Rectal Cancer
Recruiting NCT06811116
Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial
Advanced Hepatocellular Carcinoma · Metastatic Hepatocellular Carcinoma · Stage III Hepatocellular Carcinoma AJCC v8
Recruiting NCT05691491
Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness
Advanced Malignant Solid Neoplasm · Advanced Microsatellite Stable Colorectal Carcinoma · Hematopoietic and Lymphatic System Neoplasm
Not yet recruiting NCT07738484
AI-Assisted Optical Diagnosis (CADx) for Diminutive Colorectal Polyps
Colorectal Polyps · Colorectal Adenoma · Diminutive Colorectal Polyp
Not yet recruiting NCT07738939
IKS04 Regimen in Advanced Solid Tumors That Express CA242
Colorectal Cancer · Gastro Esophageal Junctional Cancer · Gastric Cancer (GC)
Recruiting NCT06662786
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
Colorectal Neoplasms
Recruiting NCT07629817
Surgery vs. Radical Chemoradiotherapy for Esophageal SCC After Neoadjuvant Immunochemotherapy
Esophageal Squamous Cell Carcinoma
Not yet recruiting NCT07733427
Evaluating the Effectiveness of AIT in the Treatment of Pain Related to Pancreatic Cancer
Pancreatic Cancer Pain · Intrathecal Analgesic · Intrathecal Administration of the Drug
Enrolling by invitation NCT06458998
Getting To Implementation: Improving Cancer Screening for Veterans
Cancer of Liver · Cancer of Colon · Cirrhosis
Recruiting NCT06607302
Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study
Cholangiocarcinoma
Recruiting NCT07252232
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
Pancreatic Cancer · PDAC · PDAC - Pancreatic Ductal Adenocarcinoma
Recruiting NCT05213598
Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment
Congenital Heart Disease
Recruiting NCT06750094
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Colorectal Neoplasms
Recruiting NCT06374875
Fibrosis Lessens After Metabolic Surgery
Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) · Non-Alcoholic Fatty Liver Disease · Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Recruiting NCT07268131
TITAN-HCC: Neoadjuvant and Adjuvant QL1706 With TACE in Resectable Hepatocellular Carcinoma Beyond Milan Criteria
Hepatocellular Carcinoma (HCC)
Recruiting NCT06934525
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
Obsessive Compulsive Disorder (OCD) · Pediatric Anxiety Disorders · Anxiety Disorder
Recruiting NCT07013916
Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH)
MASH - Metabolic Dysfunction-Associated Steatohepatitis · MASH With Fibrosis · Steatosis of Liver
Recruiting NCT04912765
Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
Hepatocellular Carcinoma · Hepatocellular Cancer · Colorectal Cancer
Recruiting NCT06305624
Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease
Alcohol Use Disorder · Alcohol-related Liver Disease
Recruiting NCT05534087
Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12)
Colon Cancer
Recruiting NCT07740122
AI-Based Stool Image Analysis for Colorectal Neoplasia Risk Assessment
Colorectal Neoplasms
Recruiting NCT07740382
Comparative Effects of ESP Block and EOIP Block on Postoperative Respiratory Recovery Following Liver Resection
Liver Resection · Upper Abdominal Surgeries
Recruiting NCT05803382
Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers
Metastatic Colorectal Carcinoma · Metastatic Malignant Solid Neoplasm · Stage IV Colorectal Cancer AJCC v8
Recruiting NCT06901531
A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer
Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer · Locally Advanced Unresectable Gastric Adenocarcinoma or Cancer · Metastatic Gastric Adenocarcinoma or Cancer
Not yet recruiting NCT07731373
Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)
Polycystic Ovary Syndrome (PCOS) · Metabolic Dysfunction-Associated Steatotic Liver Disease · Pediatric Obesity
Enrolling by invitation NCT07735650
Immunosuppressant Withdrawal Based on Parenchymal Chimerism in the Liver Transplantation
Liver Transplantation · Liver Transplantation in Long-term
Recruiting NCT07736963
Discontinuation Recommendations for GLP-1 Receptor Agonists Prior to Colonoscopy: A Randomized Controlled Trial in Taiwan.
GLP-1
Recruiting NCT04657068
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
Advanced Cancer · Metastatic Cancer · Ovarian Cancer
Not yet recruiting NCT07733817
Impact of Probiotics on Neuropathy Induced by Adjuvant Chemotherapy in Patients With Colon Cancer.
Colon Adenocarcinoma · Neuropathic Pain
Not yet recruiting NCT07738055
Study on the Combined Treatment of Hepatocellular Carcinoma With Envafolimab, Suvemcitug and HAIC Conversion
Potentially Resectable Hepatocellular Carcinoma
Recruiting NCT07636382
Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy in Patients With Cancer-Related Celiac Pain
Advanced Cancer · Pancreatic Cancer
Not yet recruiting NCT06786429
Managing Hepatitis B (Hep. B) and Human Papilloma Virus (HPV) Related Cancers and Mental Health.
Hepatitis B · Human Papilloma Virus · Mental Health Issue
Not yet recruiting NCT07735624
RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer
Early Rectal Cancer · Stage I Rectal Cancer · Microsatellite Stable Rectal Carcinoma
Recruiting NCT06622057
D07001 Softgel-Capsules and Capecitabine Combination Therapy in Patients With Advanced Biliary Tract Cancer
Biliary Tract Cancer (BTC)
Recruiting NCT07082530
A RCT of Labor Induction at 39 Weeks in Low - Risk Women in China
Cesarean Delivery
Recruiting NCT06638502
Safety of HRX215 in Patients After Minor and Major Liver Resection
Liver Resection · Colorectal Carcinoma Liver Metastases
Not yet recruiting NCT07736105
Optimizing Dysphagia Treatment Delivery in Acute Care: A Hybrid Efficacy Implementation Trial
Dysphagia · Critical Illness
Recruiting NCT06252649
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Metastatic Colorectal Cancer
Recruiting NCT07736495
Protective Role of Alpha-Lipoic Acid in Chemotherapy-Induced Mucositis
Colorectal Cancer
Not yet recruiting NCT07736612
A Pan-RAS Inhibitor in Combination With Anti-Tumor Therapy in Participants With Advanced Pancreatic Cancer
Pancreatic Cancer · RAS Mutations or Amplifications
Not yet recruiting NCT05932914
Liver Biopsy Following Gene Therapy For Hemophilia
Hemophilia A · Hemophilia B
Recruiting NCT07737171
Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions
Pancreatic Cancer
Recruiting NCT07736911
Discontinuation One Week Recommendations for GLP-1 Receptor Agonists Prior to Esophagogastroduodenoscopy.
GLP-1
Enrolling by invitation NCT05821634
Personalizing Treatment Delivery
Anxiety Disorders and Symptoms · PTSD and Trauma-related Symptoms · Alcohol; Use, Problem; Alcohol Use Disorder
Not yet recruiting NCT07731360
Non-Invasive Diagnostic Panel for MASLD in Children With Obesity
Metabolic Dysfunction-Associated Steatotic Liver Disease · Pediatric Obesity · Insulin Resistance Syndrome
Recruiting NCT07143968
A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease · HIV (Human Immunodeficiency Virus)
Recruiting NCT07392892
Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction , or Esophageal Adenocarcinoma · Metastatic Gastric Cancer · Gastroesophageal Junction Cancer
Recruiting NCT04634643
Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
NAFLD
Recruiting NCT07534241
Hepatoprotective Effects of Reishi Mushroom- (Ganoderma Lucidum) Among Metabolic Dysfunction-associated Fatty Liver Disease Patients
Lipid Profile · Liver Biomarkers
Not yet recruiting NCT07738042
To Explore a Single-arm Phase II Study on Intestinal Microbiota Transplantation Combined With Neoadjuvant Immunotherapy and Chemoradiotherapy for Locally Advanced Rectal Cancer Under MSS/pMMR
Locally Advanced Rectal Cancer (LARC)
Recruiting NCT07254910
Feasibility of a Multi-Channel Intervention to Promote Colorectal Cancer Screening Among American Indians in Oklahoma
CRC Screening · CRC (Colorectal Cancer)
Recruiting NCT07737340
Metabolic Liver Disease in Newly Diagnosed People Living With HIV (MASHIV-TR)
HIV Infections · Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) & Steatohepatitis (MASH) · Fatty Liver
Recruiting NCT07738094
Cold and NSAID Trial for Prevention of Post-ERCP Pancreatitis
Pancreatitis, Acute
Recruiting NCT07405151
A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)
Oesophageal Squamous Cell Carcinoma
Not yet recruiting NCT07734766
Ebastine for Adjuvant Treatment of Tumor Budding-Positive Liver Cancer After Surgery
Hepato Cellular Carcinoma
Recruiting NCT07191886
Measuring Patient Reported Needs in Outpatient Liver Disease Management
Chronic Liver Disease · Cirrhosis, Liver
Recruiting NCT06937671
Randomized Trial of Cold EMR Compared to Hybrid Cold EMR.
Polyp of Colon · Endoscopic Mucosal Resection
Recruiting NCT07733115
QL1706（Iparomlimab/Tuvonralimab) Combined With Gemcitabine and Cisplatin as First-Line Treatment for PD-L1-Positive Biliary Tract Cancer
Biliary Tract Cancer (BTC)
Recruiting NCT07733830
Comparing ICI Followed By CCRT And CCRT Followed By Immunotherapy In Unresectable LA-ESCC
Esophageal Cancer
Recruiting NCT06723275
LEOPARD Prospective Validation Cohort 1
Decompensated Liver Cirrhosis · Primary Biliary Cholangitis · Primary Sclerosing Cholangitis
Not yet recruiting NCT07733050
Efficacy and Safety of Serplulimab in Combination With Bevacizumab and FOLFIRINOX or NALIRIFOX as Second-Line Therapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma
Not yet recruiting NCT07734857
Peripheral Blood Biomarkers and Response to Atezolizumab Plus Bevacizumab in Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Recruiting NCT07327229
A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in Participants With Claudin (CLDN) 18.2-positive, HER2-negative, Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaUnresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Recruiting NCT07525206
A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
Colorectal Cancer
Recruiting NCT07281924
Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
Metastatic Melanoma · Liver Metastases
Recruiting NCT06219941
AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2
Gastric Cancer · Gastroesophageal Junction Cancer · Biliary Tract Cancer
Not yet recruiting NCT07528430
Signature Development and Validation Protocol for an Epigenetic Assay in Diagnosing Pancreatic Cancer
Pancreatic Cancer, Advanced or Metastatic
Recruiting NCT04113382
Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy
Bowel Preparation
Recruiting NCT06445062
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Colorectal Cancer · CRC · Pancreatic Ductal Adenocarcinoma
Not yet recruiting NCT07734142
Mental Health Outcomes and Psychological Evaluation After Liver Transplantation
Liver Transplantation (LT)
Recruiting NCT07600788
A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.
Chronic Hepatitis B
Not yet recruiting NCT07732504
AI-Guided Surveillance and Curative Salvage of Recurrence After Hepatocellular Carcinoma Resection or Ablation
Hepatocellular Carcinoma (HCC)
Not yet recruiting NCT07071454
Preventing Early-Onset Colorectal Cancer in the VA
Colorectal Neoplasms · Mass Screening
Recruiting NCT07610837
Study of AZD2389 Safety, Tolerability, and Pharmacodynamics in Adults With Steatotic Liver Disease and Advanced Fibrosis
Liver Fibrosis · Hepatic Cirrhosis
Not yet recruiting NCT07732933
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
Bipolar Disorder (BD) · Bipolar Disorder (BPD)
Recruiting NCT06915753
Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations
Metastatic Hepatocellular Carcinoma · Solid Tumors · Solid Tumor, Adult
Recruiting NCT02863757
Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease
Chronic Hepatitis B · Nonalcoholic Fatty Liver Disease
Not yet recruiting NCT07509008
Phase 1/2 Window Of Opportunity Study Of TROP2 CAR/IL-15 TGFBR2 KO NK Cells Delivered Intraperitoneally For The Management Of Gastric Cancer Metastatic To The Peritoneum
Gastric Cancer, Metastatic
Recruiting NCT07430293
Hybrid Closed-Loop Insulin Delivery After Pancreatectomy
Pancreatectomy · Total Pancreatectomy · Partial Pancreatectomy
Recruiting NCT04990609
EUS-RFA PANCARDINAL-1 Trial
Pancreatic Ductal Adenocarcinoma (PDAC)
Recruiting NCT06803927
Non-Endoscopic Detection of Barrett's Esophagus Using Methylation Biomarkers on EndoSign® Cell Collection Device Samples
Barrett Esophagus
Enrolling by invitation NCT07708467
The DiNAM-EoE-C Study: Esophageal Distensibility and Novel Assessment of Motility in Eosinophilic Esophagitis
Eosinophilic Esophagitis (EoE) · Dysphagia, Esophageal
Recruiting NCT07227805
Evaluation of the Safety and Performance of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in People Living With Diabetes (NEXUS)
Diabetes (Insulin-requiring, Type 1 or Type 2)
Recruiting NCT07047807
PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Recruiting NCT07409805
YMN-136 Vaccine for Patients With Liver Metastasis of Colorectal Cancer Progressing After Third-Line Treatment
Colorectal Cancer
Recruiting NCT07016269
A Study to Evaluate the Efficacy and Safety of CnU Cap. 500 mg in Patients With Biliary Dyspepsia
Biliary Dyspepsia
Recruiting NCT06675604
LEOPARD Training and Validation Data Collection Study
Decompensated Liver Cirrhosis · Primary Biliary Cholangitis · Primary Sclerosing Cholangitis
Recruiting NCT07093346
The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Nonalcoholic Fatty Liver Disease · Nonalcoholic Fatty Liver Disease (NAFLD) · MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease
Recruiting NCT06732388
Itraconazole in Combination With Ablation for the Prevention of Esophageal Cancer in Patients With High-risk Barrett's Esophagus
Barrett Esophagus · Clinical Stage I Esophageal Adenocarcinoma AJCC v8 · Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8
Recruiting NCT03151473
Longitudinal Observational Study Of Chinese With NAFLD/NASH
Non-Alcoholic Fatty Liver Disease (NAFLD) · Non-Alcoholic Steatohepatitis (NASH)