Recruiting NCT07209787
SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic Leak
Rectal Cancer
GI & liver
8,202 trials in this section
Recruiting NCT07125521
Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare
GERD (Gastroesophageal Reflux Disease)
Recruiting NCT06106269
Outcomes and Quality of Life Following Rectal Artery Embolization for Bleeding Internal Hemorrhoids
Internal Hemorrhoid
Enrolling by invitation NCT07198945
Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection
Colon Cancer · Colon Polyp · Adenoma
Recruiting NCT07496840
Clinical Outcomes, Safety, and Effectiveness of Speedboat UltraSlim™ in Per-Oral Endoscopic Myotomy (POEM)
Esophageal Motility Disorders · Achalasia
Recruiting NCT05486572
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Carcinoma, Hepatocellular · Cirrhosis
Recruiting NCT06774300
Evaluating Telehealth Delivery of Brief Alcohol Screening and Intervention for College Students
Alcohol Consumption
Recruiting NCT06636435
A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer
Solid Tumors · Hepatocellular Carcinoma (HCC) · Malignant Melanoma
Not yet recruiting NCT07653867
Patient Controlled Propofol Sedation Versus Nurse-assisted Propofol Sedation in Diagnostic Colonoscopies With a Focus on Patient Satisfaction
Colonoscopy (Procedure)
Recruiting NCT05829291
Alpha Radiation Emitters Device (DaRT) for the Treatment of Liver Metastases
Liver Metastases
Not yet recruiting NCT07640022
Optimization of Coronary Sinus Lead Placement for CRT Delivery in Non-LBBB or Narrow LBBB Patterns Using Multiparametric 82Rubidium PET-CT Scan Analysis and Cardiac CT Venography
Heart Failure
Not yet recruiting NCT07649473
QL1706 Combined With Standard Therapy for Conversion Therapy of Synchronous Liver Metastases From Colon Cancer: a Multicenter, Single-arm, Exploratory Study
Colon Cancer · Synchronous Liver Metastases
Not yet recruiting NCT07650773
CHARM Hepatocellular Carcinoma MEA Study
HepatoCellular Carcinoma
Recruiting NCT06764875
A Phase Ⅲ Study of Rilvegostomig in Combination With Fluoropyrimidine and Trastuzumab Deruxtecan as the First-line Treatment for HER2-positive Gastric Cancer
HER2-positive Gastric Cancer · Gastroesophageal Junction Adenocarcinoma
Recruiting NCT06843434
A Study of Botensilimab and Balstilimab for Rectal Adenocarcinoma
Microsatellite Stable Rectal Carcinoma · Locally Advanced Rectal Adenocarcinoma
Not yet recruiting NCT07440342
TEAS for Sedation During ERCP: A Multicenter Trial With Mechanistic Substudy
Endoscopic Retrograde Cholangiopancreatography · Conscious Sedation Adverse Event · Procedural Pain
Not yet recruiting NCT07651137
Impact of Culture of Perfusion Fluid on Donor-derived Infection Management and Outcome in Liver and Kidney Transplant
Liver Transplant Infection · Kidney Transplant Infection · Liver Transplant
Recruiting NCT07651553
Transanal Total Mesorectal Excision vs Robotic Total Mesorectal Excision
Rectal Cancer Patients · Robotic Assisted Intervention
Recruiting NCT07547553
A Phase Ib/II Trial to Evaluate the Efficacy and Safety of HH-009 for the Treatment of FGF19-positive Advanced or Unresectable HCC
Advanced or Unresectable Hepatocellular Carcinoma (HCC)
Enrolling by invitation NCT07651748
Secretin in Ex-situ Liver Perfusion
Liver Transplantation
Recruiting NCT06698458
Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer
Pancreatic Cancer · Pancreatic Adenocarcinoma · Metastatic Pancreatic Cancer
Recruiting NCT07433751
Ultrasound Estimation of Fetal Macrosomia at Term: Diagnostic Accuracy Within 24 Hours of Delivery
Macrosomia · Fetal Weight
Not yet recruiting NCT07649746
Opioid-Free Versus Opioid-Based Sedation for Endoscopic Procedures
Sedation · Endoscopy · Colonoscopy
Recruiting NCT04506593
Indiana University Gastrointestinal Motility Diagnosis Registry
Eosinophilic Esophagitis · Gastroesophageal Reflux Disease (GERD) · Gastroparesis
Recruiting NCT06026943
Alpha Radiation Emitters for the Treatment of Pancreatic Cancer for the Treatment of Locally Advanced Pancreatic Cancer
Pancreatic Cancer · Unresectable Pancreatic Cancer · Pancreatic Adenocarcinoma
Recruiting NCT07309991
Postoperative Hypoxemia Increases the Risk of Anastomotic Leak After Radical Esophagectomy
Esophageal Carcinoma · Esophageal Adenocarcinoma · Esophagectomy
Recruiting NCT07559474
A Study to Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment
Hepatic Insufficiency · Liver Diseases
Not yet recruiting NCT07649980
Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II
Biliary Tract Cancer (BTC) · EGFR-positive Advanced Biliary Tract Carcinoma
Recruiting NCT06963047
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum Period
Recruiting NCT07187154
The Application of Symptoms Management Program Based on the Patient Reported Outcome After Esophagectomy
Esophageal Cancer
Not yet recruiting NCT07651007
Short-course RT Followed by NALIRIFOX Plus Pucotenlimab as Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer With MSS/pMMR
Advanced Rectal Cancer
Recruiting NCT04367987
Variability of Heart Rate as a Marker of Complication of Colorectal Surgery
Surgery--Complications
Recruiting NCT05030571
The Effects of Double Plasma Molecular Adsorption System in Acute on Chronic Liver Failure Patients
Acute-On-Chronic Liver Failure · Acute on Chronic Hepatic Failure
Not yet recruiting NCT07558304
Suprapapillary Metal Stent vs. Routine Transpapillary Drainage in Malignant Hilar Biliary Obstruction (SMART-B Trial)
Cholangiocarcinoma · Bile Duct Neoplasms · Malignant Biliary Obstruction
Not yet recruiting NCT07649512
Progressive Muscle Relaxation Delivered Via Virtual Reality - an Intervention for Patients Undergoing Cellular Therapy
Heme Malignancy
Recruiting NCT06642844
Bevacizumab-based Chemotherapy Adapted to Bevacizumab Pharmacokinetics in 1st-line Treatment
Unresectable Metastatic Colorectal Cancer
Recruiting NCT04503785
Esophageal Impedance and Manometry Measurements and Dysphagia Symptom Scoring
Dysphagia, Esophageal
Recruiting NCT07650344
USAGE OF ARITIFICIAL INTELLIGENCE IN AIDING WITH COLONIC SESSILE SERRATED LESIONS DETECTION AND DIAGNOSIS (AI-SSL)
Sessile Serrated Lesion · CADe
Recruiting NCT06898177
Development and Testing of a Mobile App to Scale Delivery of Cognitive-behavioral Therapy for Avoidant/Restrictive Food Intake Disorder
Avoidant/Restrictive Food Intake Disorder (ARFID)
Not yet recruiting NCT07649655
EMB-01 in Combination With Chemotherapy for Unresectable or Metastatic Colorectal Cancer
Unresectable/Metastatic Colorectal Cancer
Recruiting NCT07649928
A Study of Dose Escalation of ES502 in Patients With Advanced Pancreatic Cancer
Pancreatic Cancer
Recruiting NCT07337590
Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar
Colorectal Cancer
Recruiting NCT07651644
Two-component Radiology-guided Autonomous Cascade Engine (TRACE)
Gastric Cancer (Diagnosis)
Recruiting NCT07576920
Anxiety Levels in Living Liver Donors
Anxiety Postoperative
Recruiting NCT07651358
A Tailored, Web-based Program (COMPASS) to Improve Exercise and Dietary Changes in Stage I-III Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy
Stage I Pancreatic Cancer AJCC v8 · Stage II Pancreatic Cancer AJCC v8 · Stage III Pancreatic Cancer AJCC v8
Enrolling by invitation NCT05047289
Indiana University Gastric Electrical Stimulation Registry
Gastroparesis
Not yet recruiting NCT07647601
Video Versus Verbal Preoperative Education in Elective Cesarean Delivery
Preoperative Anxiety · Cesarean Delivery · Stress Response
Recruiting NCT06626074
Exploratory Study of MRI Biomarkers of NASH
Non-alcoholic Fatty Liver Disease NAFLD
Recruiting NCT05657743
Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic Cancer (Feasibility and Safety)
Pancreatic Cancer · Unresectable Pancreatic Cancer · Metastatic Pancreatic Cancer
Not yet recruiting NCT07649811
Endoscopic vs Non-endoscopic Drainage for Benign Gallbladder Diseases in High-risk Patients or Patients Desiring Gallbladder Preservation
Gallbladder Diseases · Cholecystitis, Acute · Cholelithiasis
Recruiting NCT06479239
Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
Pancreas Cancer · Pancreatic Cancer
Recruiting NCT07071441
Indomethacin vs Diclofenac for Preventing PEP
ERCP · Pancreatitis · Non-steroidal Anti-inflammatory (NSAID)
Recruiting NCT06964438
Postoperative Electrical Muscle Stimulation Two
Surgery · Colorectal Cancer · Muscle Atrophy
Recruiting NCT03711890
Ultra-High Resolution Optical Coherence Tomography in Detecting Micrometer Sized Early Stage Pancreatic Cancer in Participants With Pancreatic Cancer
Pancreatic Carcinoma · Pancreatic Intraductal Papillary Mucinous Neoplasm, Pancreatobiliary-Type
Recruiting NCT07646639
Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC
Rectal Cancer · Radiotherapy
Recruiting NCT07106580
Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Via Capsules for Intestinal Multidrug-resistant Bacteria Decolonization
Colonization, Asymptomatic
Recruiting NCT07594977
Food-Effect, Single and Multiple Dose Pharmacokinetics, Safety and Tolerability Study of 4-MUST, 128 mg, Tablets in Healthy Volunteers
Chronic Cholecystitis · Biliary Dyskinesia
Not yet recruiting NCT07648589
Glucose Homeostasis and Shared Genetic Factors in Colorectal Cancer
Colorectal Cancer · Diabetes Mellitus · Glucose Homeostasis
Recruiting NCT04048278
Lidocaine Infusion in Pancreatic Cancer
Pancreatic Cancer
Recruiting NCT01401998
ARPKD Database Study
Hepato/Renal Fibrocystic Disease · Autosomal Recessive Polycystic Kidney Disease · Joubert Syndrome
Recruiting NCT06972147
Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis
Eosinophilic Esophagitis
Not yet recruiting NCT07639853
Case-Specific Health Care Professional Clinical Survey for Concerto Versa™ Detachable Coils
Arteriovenous Malformation · Gastrointestinal Bleed · Gastric Varices
Enrolling by invitation NCT04457193
Outcomes After Transoral Incisionless Fundoplication (TIF) Following Successful Endoscopic Ablation for Barrett's Esophagus
Barrett Esophagus · Transoral Incisionless Fundoplication
Recruiting NCT05943210
The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer
Rectal Cancer
Not yet recruiting NCT07647731
Endoscopic Calcium Electroporation in Gastric Tumors
Calcium Electroporation for Hemostasis in Gastric Neoplasms
Recruiting NCT06015607
Testing of GripTract-GI Endoscopic Tissue Manipulator for Use During Complex Endoscopic Polypectomies in the Colon
Polyps Colorectal
Recruiting NCT07649057
A Study of a Urine Test to Detect Colorectal Cancer
Colorectal Cancer · Precancerous Polyp · Rectal Bleeding
Recruiting NCT07335042
Prediction Model for MINS After Major Hepatobiliary Surgery
Myocardial Injury After Noncardiac Surgery (MINS) · Postoperative Complications · Liver Neoplasm
Not yet recruiting NCT07643779
Symptom Severity, Posture, Pain, and Physical Activity in Gastroesophageal Reflux Disease
Gastroesophageal Reflux Disease (GERD) · Symptom · Musculoskeletal Pain
Recruiting NCT05561907
Enteral Anastomosis for the Treatment of Gastric Outlet Obstruction: A Randomized Controlled Study Comparing Endoscopic Versus Surgical Gastrojejunostomy
Gastric Outlet Obstruction
Not yet recruiting NCT07638956
ICG in Colon Cancer
Colon Cancer · ICG (Indocyanine Green)
Not yet recruiting NCT07645118
Brachytherapy Followed by Nivolumab Prior to Surgery in Rectal Cancer
Locally Advanced Rectal Cancer
Recruiting NCT07644091
Psychosocial Burden and Quality of Life in Caretakers of Hepatobiliary Cancer Patients
Psychosocial Problem
Not yet recruiting NCT07645079
Automated Insulin Delivery Versus Daily Injections for Hospital Diabetes Care
Diabetes Mellitus Type 2 · Infection · CGM
Recruiting NCT07058012
A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)
Colo-rectal Cancer
Not yet recruiting NCT07643909
Health-Related Social Needs Food Boxes Delivery Program
Food Insecurity
Recruiting NCT05630794
Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
Colorectal Adenomatous Polyp · Colorectal Carcinoma · Familial Adenomatous Polyposis
Not yet recruiting NCT07646574
Non-surgical Management After NIT for dMMR/MSI-H GC
Non-surgical Management;dMMR/MSI-H Gastric Cancer;Neoadjuvant Immunotherapy
Recruiting NCT07574970
A COMBINATION OF RECTAL INDOMETHACIN AND COLD WATER EXPOSURE OF THE AMPULLA AFTER ERCP IS SUPERIOR TO RECTAL INDOMETHACIN ALONE IN REDUCING THE INCIDENCE OF POST-ERCP PANCREATITIS -RCT
Pancreas Disease
Recruiting NCT06459869
NG-350A Plus Chemoradiotherapy for Locally Advanced Rectal Cancer
Locally Advanced Rectal Cancer (LARC)
Not yet recruiting NCT07644208
PD-1/IL-2 Bispecific Antibody as Neoadjuvant Therapy for Early Recurrent Hepatocellular Carcinoma After Curative Hepatectomy
Hepatocellular Carcinoma (HCC)
Not yet recruiting NCT07643857
Circular Staplers and Anastomotic Leak After Colorectal Surgery
Colorectal Cancer Postoperative Complications
Not yet recruiting NCT07612007
HRX215, A First Generation MKK4 Inhibitor Drug, for the Treatment of Patients With Colorectal Liver Metastasis After Undergoing a Portal Vein Embolization
Metastatic Colorectal Carcinoma · Metastatic Malignant Neoplasm in the Liver · Resectable Colorectal Carcinoma
Recruiting NCT07644286
A Phase II Study of Pirfenidone Plus PD-1 Inhibitor With or Without Hypofractionated Radiotherapy for Refractory pMMR/MSS Colorectal Cancer
Colorectal Cancer (CRC)
Recruiting NCT05239546
Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers
Colon Cancer · dMMR Colorectal Cancer
Recruiting NCT07575191
Safety and Performance of a Novel Infusion Catheter System for Peri/Intratumoral Gemcitabine Delivery in Patients With Pancreatic Cancer
Pancreatic Cancer Non-resectable
Enrolling by invitation NCT07646340
Long-term Pelvic Floor and Sexual Health After Obstetric Anal Sphincter Injury in Finland
Obstetric Anal Sphincter Injury · Sexual Dysfunction and the Mode of Deliveries · Pelvic Floor Disorders
Recruiting NCT07351071
Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections
Colorectal Anastomosis · Left-sided Colon Resection · Anastomotic Leak
Recruiting NCT07011576
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
Colon Cancer · Rectal Cancer · Colorectal Cancer
Recruiting NCT06861478
PPIs and In-Hospital Morbidity in Acute Variceal Bleeding With Chronic Liver Disease
Morbidity
Recruiting NCT06369259
Open-label Phase 2 Study of Avutometinib (RAF/MEK Clamp) in Combination With Defactinib (FAK Inhibitor) and Cetuximab in Patients With Unresectable, Anti-EGFR-Refractory Advanced Colorectal Cancer
Advanced Colorectal Cancer
Not yet recruiting NCT07318389
ASCEND-CRC: Profiling and Targeting Dynamic Tumor Resistance in Patients With Metastatic Colorectal Cancer
Dynamic Tumor Resistance · Metastatic Colorectal Cancer
Not yet recruiting NCT07642323
Safety and Efficacy of NOM and OPFS Versus RO for dMMR/MSI-H or POLE-Mutated Gastrointestinal Cancers
Gastrointestinal Cancers · Gastrointestinal Cancers - Stomach · Gastrointestinal Cancers - Colorectal
Enrolling by invitation NCT07631442
Using Digital Health Technology to Monitor Patients With Primary Biliary Cholangitis (PBC)
Primary Biliary Cholangitis (PBC)
Not yet recruiting NCT07643623
Neoadjuvant and Adjuvant Therapy Studies of Sintilimab Combined With Chemotherapy With or Without Ipilimumab N01 in Resectable Gastric/Gastroesophageal Junction Adenocarcinoma
Resectable Gastric/Gastroesophageal Junction Adenocarcinoma
Recruiting NCT06363266
A SMART Design to Optimize the Delivery of TEMPO for Men With Prostate Cancer and Their Caregivers
Cancer of the Prostate · Anxiety
Not yet recruiting NCT07640880
Lipidomic and Multi-Omics Profiling of Fatty Liver Disease in People With and Without HIV
MASLD · HIV (Human Immunodeficiency Virus)
Not yet recruiting NCT07643727
Development of Fluorescent Lectin Tracers With Dedicated Technology for in Vivo Detection of Esophageal Dysplasia in Barrett Patients
Barrett's Esophagus With or Without Dysplasia · Barrett Esophagus Adenocarcinoma
Recruiting NCT05890365
Increased Risk of Non-alcoholic Fatty Liver Disease in Low Birth Weight Individuals
Non-Alcoholic Fatty Liver Disease · Low Birth Weight
Recruiting NCT07011147
Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery
Type 1 Diabetes (T1D) · Type 2 Diabetes · Diabetes, Autoimmune