Recruiting NCT06264219
Restoration of the Gut Microbiome After Cesarean Section
Microbial Colonization
GI & liver
8,202 trials in this section
Recruiting NCT07529626
Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer
Pancreatic Tumor, Benign · Pancreatic Cancer, Adult · Pancreatic Cancer Resectable
Recruiting NCT07378072
Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity
MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease)
Recruiting NCT07670273
Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer
Biliary Tract Neoplasms Immunotherapy
Recruiting NCT07672145
Comparison of Gallbladder Extraction Via Subxiphoid vs Infraumbilical Port in Laparoscopic Cholecystectomy
Cholelithiasis (Without Cholecystitis) · Cholecystitis, Acute
Recruiting NCT06814509
Delivering HOPE (Helping Women Optimize Prenatal Equity)
Gestational Weight Gain · Diet, Healthy · Gestational Hypertension
Recruiting NCT07605819
Pancreatic Cancer Screening Using the Enzeavour Assay in Japan
Pancreatic Cancer · Pancreatic Neoplasms
Enrolling by invitation NCT03103789
Assessment of Esophageal Epithelium Integrity With Use of a Novel Mucosal Impedance Device
Gastro Esophageal Reflux
Not yet recruiting NCT07110233
Yttrium-90 Radiation Segmentectomy for Hepatocellular Carcinoma
Hepatocellular Carcinoma · Unresectable Hepatocellular Carcinoma · Hepatocellular Cancer
Recruiting NCT07671625
Comprehensive Perioperative Program Based on Prehabilitation, Nutritional Intervention and Psychological Support for Patients With Locally Advanced Operable Oesophagogastric Cancer
Locally Advanced Esophageal Cancer · Gastroesophageal Junction Cancer · Gastric Cancer
Recruiting NCT07670286
Spatial Multi-omics and Intelligent Early Warning of Pancreatic Cancer Cachexia
Pancreatic Cancer · Cachexia; Cancer; Sarcopenia
Recruiting NCT07019844
PSMA PET for the Staging and Management of Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Recruiting NCT07527910
A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Not yet recruiting NCT07670871
Exocrine-Endocrine Pancreatic Crosstalk: Precision Pathways to Reframe Diabetes Pathophysiology
Type 2 Diabetes Mellitus (T2DM) · Chronic Pancreatitis · Prediabetes
Recruiting NCT07304843
A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction
Primary Biliary Cholangitis (PBC)
Recruiting NCT07262567
Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic Cancer
Metastatic Pancreatic Cancer
Not yet recruiting NCT07665372
Liver Transplantation From Donors With HIV: Impact on Opportunistic Infections, Cancer, and Long-Term Outcomes (Expanding HOPE Liver)
HIV
Not yet recruiting NCT07671599
Perioperative Use of Continuous Glucose Monitoring for Scheduled Cesarean Deliveries (PERUSE)
Dysglycemia
Recruiting NCT07120906
Augmented Reality Real-Time Guidance for MRI-Guided Interventions
Liver
Recruiting NCT05319730
A Study to Evaluate Investigational Agents With or Without Pembrolizumab (MK-3475) in Participants With Advanced Esophageal Cancer Previously Exposed to Programmed Cell Death 1 Protein (PD-1)/ Programmed Cell Death Ligand 1 (PD-L1) Treatment (MK-3475-06B)
Esophageal Squamous Cell Carcinoma
Recruiting NCT06412198
A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations
Metastatic Colorectal Cancer · KRAS G12C Mutations
Recruiting NCT07672392
The Effect of a Post-operative Exercise Programme Versus Standard Care on Physical Fitness of Patients With Breast Cancer Undergoing Deep Inferior Epigastric Perforator (DIEP) Flap Reconstruction Surgery
Breast Cancer · Exercise
Recruiting NCT07671339
A Study of ELI-002 7P, With or Without Tislelizumab, in People With Pancreatic Cancer
Pancreatic Cancer
Recruiting NCT07669298
Active Surveillance vs Adjuvant Chemoradiotherapy for Locally Resected Intermediate-Risk T1 Rectal Cancer
Rectal Cancer
Recruiting NCT07632235
A Multicenter, Prospective, Randomized, Open-label Phase Ib/II Study of Celecoxib Plus Pembrolizumab and Gemcitabine/Cisplatin Versus Pembrolizumab and Gemcitabine/Cisplatin in Patients With CK5/6-High Unresectable Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma
Intrahepatic Cholangiocarcinoma (Icc)
Not yet recruiting NCT07594990
The MAI-FOIE Cohort
Autoimmune Liver Diseases · Immunological Mechanisms
Recruiting NCT07385703
Clinical Study on the Efficacy and Safety of LM-302 Injection Combined With Tislelizumab and Tislelizumab Combined Chemotherapy for the Treatment of Gastric or Gastroesophageal Junction Adenocarcinoma.
Adenocarcinoma
Not yet recruiting NCT07663487
A Study Evaluating the Safety and Efficacy of Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres to Bridge or Downstage Patients With Hepatocellular Carcinoma (HCC) to Liver Transplant or Resection and Elicit Pathologic Necrosis.
Hepatocellular Carcinoma (HCC)
Recruiting NCT04903223
Liver Adiposity Effects on Pediatric Statin
Cholesterol; Lipidosis
Not yet recruiting NCT07668765
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Morbid Obesity · Anorectal Diseases · Drug-Related Side Effects and Adverse Reactions
Recruiting NCT06205849
Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer
Pancreatic Cancer
Recruiting NCT07668453
An Open-label, Single-arm, Multicenter Exploratory Study of Adebrelimab Combined With Gemcitabine and Albumin-bound Paclitaxel as First-line Treatment for Biliary Tract Malignancies
Biliary Tract Neoplasms
Recruiting NCT07669454
A Randomized, Double-blind, Placebo-controlled, Parallel-group, Comparative, Phase III Study to Evaluate the Efficacy and Safety of Nuvastatic® 300mg Capsule in Reducing Cancer-Tumor in Patients With Metastatic Colorectal Cancer Receiving Standard Chemotherapy.
Fatigue Related to Cancer Treatment · Colon Cancer
Recruiting NCT07669519
Evaluation of NuvastaticTM in Reducing Cancer-Related Fatigue in Stage IV Colon Cancer Patients Undergoing First-Line Chemotherapy
Fatigue · Colon Cancer
Recruiting NCT07642336
Erector Spinae Plane Block Versus Thoracic Epidural Analgesia for Open Liver Resection
Liver Neoplasms · Hepatic Resection · Liver Cancer
Recruiting NCT03801876
Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer
Clinical Stage I Esophageal Adenocarcinoma AJCC v8 · Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8 · Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8
Recruiting NCT07166406
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
Advanced Hepatocellular Carcinoma · Stage III Hepatocellular Carcinoma AJCC v8 · Stage IV Hepatocellular Carcinoma AJCC v8
Recruiting NCT07588386
The Value of Early Postoperative Colonoscopy in The Early Diagnosis of Anastomotic Leakage After Surgery for Low Colorectal Cancer
Anastomotic Leakage
Not yet recruiting NCT07656766
Sintilimab Plus Gossypol Acetate in Advanced Colorectal Cancer
Advanced Colorectal Cancer
Not yet recruiting NCT07668024
Study of Occupational Risk Factors for Biliary and Pancreatic Cancers
Biliary Tract Cancer · Pancreatic Cancer
Recruiting NCT07365007
A Virtually Delivered Diet Intervention (LASO-3) for the Improvement of Chemotherapy-Induced Peripheral Neuropathy in Cancer Survivors Post-treatment
Chemotherapy-Induced Peripheral Neuropathy · Hematopoietic and Lymphatic System Neoplasm · Malignant Solid Neoplasm
Recruiting NCT07042919
Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer
Advanced Hepatocellular Carcinoma · Cirrhosis · Stage III Hepatocellular Carcinoma AJCC v8
Recruiting NCT06543316
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment
Roux-en-y Anastomosis Site · Marginal Ulcer · Marginal Ulcer (Peptic) or Erosion
Recruiting NCT07669220
A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial)
Rectal Adenocarcinoma · High-risk Locally Advanced · Short-course Radiotherapy (SCRT)
Enrolling by invitation NCT06597955
Large-Scale Implementation of a Decision Aid About Colorectal Cancer Screening
Colorectal Cancer Screening
Recruiting NCT06824974
Time-restricted Eating and Healthy Eating in Patients With Metabolic Liver Disease or Cancer
Liver Cancer, Adult · MASH - Metabolic Dysfunction-Associated Steatohepatitis · Obesity and Overweight
Recruiting NCT06958328
Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer
Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma · Stage II Pancreatic Cancer AJCC v8 · Stage III Pancreatic Cancer AJCC v8
Recruiting NCT06553651
Necrosectomy With Cryotechnology for Accelerated Removal
Pancreatic Necrosis · Acute Pancreatitis · Acute Pancreatic Necrosis
Enrolling by invitation NCT07346274
Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy
Serum Lactate Post-pancreatic Duodenectomy
Not yet recruiting NCT07669740
A Study on the Efficacy and Safety of Sintilimab Combined With Ramucirumab and Paclitaxel in the Treatment of Gastric Cancer Patients With Short-term Recurrence After Adjuvant Therapy
Gastric Cancer (Diagnosis)
Recruiting NCT06871579
Study of the Esophageal String Test (EST) for the Diagnosis of Helicobacter Pylori
Helicobacter Pylori
Recruiting NCT06346197
Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas
Gastric Cancer · MSI-H · Metastatic Cancer
Not yet recruiting NCT07219745
Transanal Irrigation for the Management of Early Low Anterior Resection Syndrome (LARS)
Colorectal Cancer · Low Anterior Resection Syndrome
Enrolling by invitation NCT07662902
Ulcerative Colitis Permeability
Ulcerative Colitis (UC) · Steatotic Liver Disease · Intestinal Permeability
Not yet recruiting NCT07668570
SBRT Plus QL1706 as Second-Line Therapy for Hepatocellular Carcinoma
HCC - Hepatocellular Carcinoma
Recruiting NCT06068491
Veteran-Centered Care for Advanced Liver Disease (Vet-CALD)
Liver Diseases
Not yet recruiting NCT07667608
Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource Settings
Cirrhosis of the Liver · Ascites · Pleural Effusion Disorder
Not yet recruiting NCT07668778
Evaluation of a Modified Bowel Preparation Regimen in Cirrhotic Patients Undergoing Colonoscopy
Cirrhosis · Bowel Preparation
Not yet recruiting NCT07667894
Mindfulness Intervention for Emotional Distress (MIED) in Patients With GERD
Gastroesophageal Reflux Disease · Emotional Distress
Recruiting NCT06138821
Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial
Obesity · Liver Diseases · Liver Fibrosis
Not yet recruiting NCT07665684
Samuraciclib in Combination With Gemcitabine/Nab-Paclitaxel in Patients With Metastatic Basal-Like Pancreatic Cancer
Pancreas Ductal Adenocarcinoma · Pancreas Cancer, Metastatic · Pancreatic Adenocarcinoma Metastatic
Recruiting NCT07664891
Metabolic Reprogramming and Microenvironment in Pancreatic Adenocarcinoma
Pancreatic Adenocarcinoma Metastatic
Enrolling by invitation NCT02427269
University of North Carolina (UNC) Barrett's Esophagus and Esophageal Cancer Biorepository
Barrett's Esophagus · Esophageal Cancer · Intramucosal Adenocarcinoma
Not yet recruiting NCT07664449
Surveillance of Neonatal Endotracheal Tube Colonisation
Ventilation, Mechanical · Ventilation-Associated Pneumonia
Recruiting NCT07253311
Evaluation of Rapid Diagnostic Device for the Detection of Candida Auris
Candida Auris Infection · Candida Auris Colonization · Nosocomial Infections
Not yet recruiting NCT04172779
Erlotinib for Hepatocellular Carcinoma Chemoprevention
Cirrhosis, Liver · Advanced Liver Fibrosis
Recruiting NCT07227051
Optimizing Self-Monitoring Feedback Delivery for the Treatment of Overweight and Obesity
Obesity & Overweight · Obesity (Disorder)
Recruiting NCT06109363
A Stepped Care Model to Deliver CBT-I in Community
Insomnia · Sleep Disturbance
Not yet recruiting NCT07390422
Duodenal pulsENDO for Suboptimally Controlled Type II Diabetes Mellitus and Steatotic Liver Disease
T2DM (Type 2 Diabetes Mellitus) · MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease · Metabolic Syndrome (MetS)
Recruiting NCT06755359
Alpha Radiation Emitters Device (DaRT) for the Treatment of Locally Advanced Pancreatic Cancer
Pancreatic Cancer · Locally Advanced Pancreatic Cancer
Not yet recruiting NCT07664813
One-Click Autofocus Versus Segmented Focus in Gastric Endoscopy
Stomach Neoplasms · Stomach Diseases
Recruiting NCT07647250
Pilot Study to Evaluate Targeted Physical Activity Among Pancreatic Cancer Patients Receiving Neoadjuvant Chemotherapy
Physiological Reactivity to Cues · Physical Exercise
Recruiting NCT06550570
Evaluation of the Impact of Ambulatory Epidural on Maternal Satisfaction During Delivery and Postpartum
Childbirth · Epidural; Anesthesia
Recruiting NCT07193862
Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis
Colorectal Cancer Metastatic
Recruiting NCT07387263
Mainstreaming Genetics: Evaluation of a Digital Application to Scale and Spread Oncologist-initiated Genetic Testing
Cancer · Breast Cancer · Prostate Cancer
Recruiting NCT06016855
Surgical Debulking Prior to Peptide Receptor Radionuclide Therapy in Well Differentiated Gastroenteropancreatic Neuroendocrine Tumors
Digestive System Neuroendocrine Tumor G1 · Digestive System Neuroendocrine Tumor G2 · Metastatic Digestive System Neuroendocrine Neoplasm
Recruiting NCT06449677
Bionic Pancreas in CFRD
Cystic Fibrosis-related Diabetes
Recruiting NCT05762991
Application of Artificial Intelligence on the Diagnosis of Helicobacter Pylori Infection and Premalignant Gastric Lesion
Helicobacter Pylori Infection · Premalignant Lesion
Recruiting NCT07660627
Determining Minimal Residual Disease Using ctDNA Deep Sequencing
Esophageal Adenocarcinoma · Gastric Cancer · Pancreatic Cancer
Recruiting NCT07419490
Utero-ovarian Transposition in Patients With Pelvic Malignancies Undergoing Whole Pelvic Radiotherapy
Colorectal (Colon or Rectal) Cancer · Pelvic Malignancies · Oncofertility
Not yet recruiting NCT07206589
Minimally Invasive Approaches for the Diagnosis of Barrett's Esophagus and Esophageal Cancer, SOS5C Trial
Barrett Esophagus · Esophageal Adenocarcinoma
Not yet recruiting NCT07665112
Algorithm-Based Timing of Delivery Using the sFlt-1/PlGF Ratio in Early-Onset Severe Preeclampsia. (MAP 2 Study : Management Based on Angiogenic Markers in Preeclampsia 2 Study )
Severe Preeclampsia
Not yet recruiting NCT07665359
Study on the Impact of Decolonization Treatment of Pneumocystis Jirovecii on the Frequency of Acute Exacerbation in COPD
Chronic Obstructive Pulmonary Disease (COPD)
Recruiting NCT07667166
Composite Index for Outcome Burden in Acute Cholangitis
Acute Cholangitis · Biliary Drainage
Not yet recruiting NCT07666256
Mesenteric Vein Access for OPVT-Related Recurrent Variceal Bleeding: An Ambispective Cohort
Occlusive Portal Vein Thrombosis (OPVT) · Cavernous Transformation of Portal Vein · Gastroesophageal Varices Bleeding
Not yet recruiting NCT07376486
Duodenal pulsENDO as an Early Treatment for Type 2 DM
Diabete Mellitus · T2 Diabetes and Fatty Liver Disease (Non-alcoholic Origin)
Recruiting NCT07636824
Efficacy and Safety of Postoperative Concurrent Chemoradiotherapy for Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma: A Multicenter Prospective Phase II Study
Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma
Not yet recruiting NCT07663188
FIB-4 Cut-Offs for Liver Fibrosis in Obese Endocrinology Patients
MASLD
Recruiting NCT06060405
Durvalumab and Oleclumab in Resectable PDAC
Pancreatic Ductal Adenocarcinoma
Recruiting NCT07660679
Effect of Preoperative CIMT on Hemodynamics During Liver Transplantation
Liver Transplantation · Carotid Intima-media Thickness
Not yet recruiting NCT07663643
Fuzheng Huayu Tablets for Metabolic Dysfunction-Associated Fatty Liver Cirrhosis (Compensated): A Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Study
Metabolic Dysfunction-associated Fatty Liver Cirrhosis
Recruiting NCT07162337
BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention
Colorectal Cancer Prevention · Colorectal Adenoma
Not yet recruiting NCT07664020
Effect of Ursodeoxycholic Acid Supplementation on Liver Regeneration in Adult Living Donor Liver Transplant (LDLT) Recipients.
Chronic Liver Disease
Recruiting NCT07066046
Artificial Intelligence-assisted Colonoscopy in the Detection and Characterization of Colorectal Lesions
Colorectal Cancer (CRC) · Adenomatous Polyposis · Colorectal Lesions
Not yet recruiting NCT07663110
Tackling Resistance And HealthCare Economics Through CPE Screening
Carbapenem-Resistant Enterobacteriaceae · Colonisation
Recruiting NCT04150640
Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma
Esophageal Adenocarcinoma · Gastric Adenocarcinoma
Recruiting NCT06840886
A Study of PHST001 in Advanced Solid Tumors
Advanced Solid Tumors · Ovarian Cancer · Endometrial Cancer
Not yet recruiting NCT07662278
rSIFN-co in Combination With Total Neo-adjuvant Therapy in Subjects With Mid-low Locally Advanced Rectal Cancer
Mid-low Locally Advanced Rectal Cancer
Recruiting NCT06402188
ColoSeal™ ICD System Safety and Feasibility Study
Colorectal Cancer
Not yet recruiting NCT07663734
Assessment of SMI (Superb Microvascular Imaging) for Characterising the Endocystic Material of Papillary Intraductal Mucinous Pancreatic Tumours (PIMPT)
Papillary and Mucinous Intraductal Tumours of the Pancreas