Recruiting NCT07644559
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC) · G12D Mutated KRAS
GI & liver
8,202 trials in this section
Not yet recruiting NCT07313787
Effects of Meal Macronutrients on Postprandial Lipids
Nephrotic Syndrome · Lipodystrophy · Metabolic Syndrome
Recruiting NCT00001971
Evaluation of Patients With Liver Disease
Hepatitis D · Hepatitis C · Hepatitis B
Recruiting NCT07162714
SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal Cancer
Rectal Cancer · Radiation · AK112
Recruiting NCT06943755
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
Pancreatic Neuroendocrine Tumor (pNET) · Extra-Pancreatic Neuroendocrine Tumor (epNET)
Recruiting NCT07422766
Comparison of Non-Invasive Mean Arterial Blood Pressure Measurements at the Arm and Ankle During Elective Cesarean Delivery.
Pregnancy · Cesarean Delivery · Blood Pressure Measurement in Pregnancy
Recruiting NCT07751302
A Randomized, Controlled, Open-Label, Multi-center Clinical Study Comparing the Efficacy of Close Follow-Up Versus Adjuvant Chemotherapy in Patients With Stage IB-IIA Gastric or Gastroesophageal Junction Adenocarcinoma Following Radical Surgery
Stage IB-IIA Adenocarcinoma of the Stomach or Gastroesophageal Junction
Recruiting NCT07733674
Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)
Glioblastoma Multiforme (GBM) · Pancreatic Ductal Adenocarcinoma (PDAC)
Not yet recruiting NCT07753577
Clinical Trial to Evaluate the Effectiveness of Liver Shear Wave Quantization Detector Spleen Stiffness Value in the Diagnosis of Esophageal Varices
Chronic Liver Diseases · Spleen Stiffness · Esophageal Varices
Recruiting NCT06997497
A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
Colon Adenocarcinoma · Rectal Adenocarcinoma
Recruiting NCT01174121
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer
Metastatic Colorectal Cancer · Metastatic Pancreatic Cancer · Metastatic Ovarian Cancer
Not yet recruiting NCT07751367
A Study on the Efficacy of Different Doses of Oryz-Aspergillus Enzyme And Pancreatin Tablet in Treating Pancreatic Exocrine Insufficiency After Gastrointestinal Surgery
Pancreatic Exocrine Insufficiency, Adul
Recruiting NCT03481829
Early Tracking of Childhood Health Determinants (ETCHED) Study
Diabetes Mellitus · Obesity · Fatty Liver
Recruiting NCT04284943
Surgical TreAtment for Obesity Related Disease and Onco-Metabolic Surgery
Gastric Cancer · Diabetes Mellitus, Type 2
Recruiting NCT01915225
Obtaining Solid Tumor Tissue From People Having Biopsy or Surgery for Certain Types of Cancer
Colorectal Neoplasms · Gastric Neoplasms · Cholangiocarcinoma
Recruiting NCT03190941
Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Pancreatic Cancer · Gastric Cancer · Gastrointestinal Cancer
Not yet recruiting NCT05722210
Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant
Hematopoietic Stem Cell Transplant
Recruiting NCT05773274
Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial
Metastatic Digestive System Neuroendocrine Tumor G1 · Metastatic Digestive System Neuroendocrine Tumor G2 · Unresectable Digestive System Neuroendocrine Tumor G1
Recruiting NCT07335523
Determine the Prevalence of Exocrine Pancreatic Insufficiency (EPI) in Pediatric and Adult Participants With Alagille Syndrome After Liver Transplantation
Exocrine Pancreatic Insuficiency
Recruiting NCT06880055
Shield Post-Approval Study Protocol
Colo-rectal Cancer
Not yet recruiting NCT07715903
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
Colorectal Neoplasms · Neoplasms · Intrahepatic Cholangiocarcinoma
Recruiting NCT07002619
ChOlanGiography Performed Routinely Versus Selectively During Cholecystectomy: A NAtional Registry-based Randomized Controlled Trial
Cholecystolithiasis · Common Bile Duct Gall Stones
Recruiting NCT07027826
The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States
Dysphagia · Eosinophilic Esophagitis
Recruiting NCT06751329
A Study of DM002 in Patients With Advanced Solid Tumors
Ovarian Neoplasms · Prostatic Neoplasms · Endometrial Neoplasms
Not yet recruiting NCT07751341
A Clinical Study of SHR-9839 as Monotherapy or in Combination With Chemotherapy Plus Adebrelimab Versus Chemotherapy Plus Adebrelimab in Patients With Advanced Esophageal Squamous Cell Carcinoma
Advanced Esophageal Squamous Cell Carcinoma
Recruiting NCT07293689
PREcision MEDicine In Achalasia (PREMEDIA) - Cohort
Type III Achalasia · EGJ Outflow Obstruction With Spastic/Hypercontractile Features · Jackhammer Esophagus
Recruiting NCT06776016
Dietary Supplements to Treat Radiation-Induced Rectal Injury
Radiotherapy · Radiation Proctitis
Recruiting NCT07562152
Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma
Pancreatic Cancer · Pancreatic Cancer Metastatic · PDAC
Recruiting NCT07751055
Neoadjuvant Chemoradiotherapy Combined With CTLA-4 Monoclonal Antibody Plus PD-1 Monoclonal Antibody for Locally Advanced Esophageal Cancer
Esophageal Squamous Cell Carcinoma (ESCC)
Recruiting NCT02595957
Genomic Services Research Program
Colon Cancer · Breast Cancer
Recruiting NCT06469944
Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06)
Gastroesophageal Junction · Gastroesophageal Adenocarcinoma · Esophageal Neoplasms
Recruiting NCT06149481
Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)
Metastatic Colorectal Cancer
Recruiting NCT07043400
A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
Metastatic Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma
Recruiting NCT06203600
Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial
Advanced Esophageal Adenocarcinoma · Advanced Gastric Adenocarcinoma · Advanced Gastroesophageal Junction Adenocarcinoma
Not yet recruiting NCT07752407
A Study to Evaluate the Efficacy and Safety of Vonoprazan 10 mg Compared to Placebo for Relief of Episodic Heartburn in Participants With Symptomatic Non-Erosive Gastroesophageal Reflux Disease Through 24 Weeks
Symptomatic Non-erosive Gastroesophageal Reflux Disease
Recruiting NCT07043270
24BRO681 : Alternating Gnp and mFOLFIRINOX for BR-PDAC
Pancreas Adenocarcinoma
Not yet recruiting NCT07750041
A Phase Ib/II Study of SYS6090 Combination Therapy in Advanced Colorectal Cancer
Unresectable Advanced or Metastatic Colorectal Cancer
Recruiting NCT07646197
Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease
MASLD · Fatty Liver
Recruiting NCT06510010
Perioperative Oxaliplatin With S-1 Combined H. Pylori Eradication in the Management of Locally Advanced Gastric Cancer
Chemotherapy Effect
Recruiting NCT05372614
Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene
Metastatic Malignant Solid Neoplasm · Metastatic Pancreatic Adenocarcinoma · Stage III Pancreatic Cancer AJCC v8
Recruiting NCT07010315
Development and Testing of a Patient-facing Educational Tool About Liver Cancer Prevention
Liver Cancer
Enrolling by invitation NCT07750275
Safety and Economics of Parenchymal Transection in Minimally Invasive Liver Surgery
Liver Surgery · MINIMALLY INVASIVE LIVER SURGERY · Liver Neoplasm
Enrolling by invitation NCT06157671
The LINFU® U.S. Registry for the Detection of Asymptomatic Pancreatic Ductal Adenocarcinoma
Pancreatic Adenocarcinoma · Pancreatic Intraepithelial Neoplasia
Recruiting NCT07114601
A Study of LY4257496 in Participants With Cancer (OMNIRAY)
Breast Neoplasms · Colorectal Neoplasms · Prostate Neoplasm
Recruiting NCT07522073
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
Solid Tumors
Not yet recruiting NCT07101666
Total Neoadjuvant Therapy With Short Course Radiation Therapy in Gastric Cancer
Gastric Cancer
Recruiting NCT07750535
LIVER STEATOSIS AND FIBROSIS IN NON-CELIAC WHEAT SENSITIVITY PATIENTS: A PROSPECTIVE STUDY
Metabolic Dysfunction-Associated Steatotic Liver Disease · Non Celiac Wheat Sensitivity · Irritable Bowel Syndrome
Recruiting NCT06324357
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Metastatic Breast Cancer · Metastatic Gastric Adenocarcinoma · Gastroesophageal Junction Adenocarcinoma
Recruiting NCT07749989
A Retrospective Analysis of Patients With Gastroesophageal Reflux Disease Based on a Prospective Clinical Dataset
Gastroesophageal Reflux Disease
Not yet recruiting NCT07749859
SHR-1701 Plus Apatinib for Second-Line Treatment in Targeted-Immune Pretreated Advanced Hepatocellular Carcinoma
Advanced Unresectable Hepatocellular Carcinoma
Recruiting NCT06335771
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity
Obesity · Nonalcoholic Fatty Liver · Diabetes Type 2
Not yet recruiting NCT07744139
Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis
Colo-rectal Cancer · Liver Metastases · Colon Cancer
Recruiting NCT07284849
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
CRC (Colorectal Cancer)
Not yet recruiting NCT07748611
SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial
Borderline Resectable Pancreatic Ductal Adenocarcinoma · Resectable Pancreatic Ductal Adenocarcinoma
Not yet recruiting NCT07749300
Trimebutine Maleate for Enhancing Gastric Visualization in Acute Upper Gastrointestinal Bleeding
Acute Upper Gastrointestinal Bleeding · Upper Gastrointestinal Bleeding · Gastrointestinal Hemorrhage
Recruiting NCT06610266
Efficacy and Safety of Weifuchun Tablet in Reversing Gastric Intestinal Metaplasia
Gastric Intestinal Metaplasia
Recruiting NCT07023354
A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems
Healthy · Hepatic Impairment
Recruiting NCT06050252
Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery
Resectable Intrahepatic Cholangiocarcinoma
Recruiting NCT07659795
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
Colorectal Cancer
Recruiting NCT07325526
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
Liver Cirrhosis
Recruiting NCT05086497
WBSI Guided Personalized Delivery of TTFields
GBM · Glioma Glioblastoma Multiforme · Tumor, Brain
Not yet recruiting NCT07750158
Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease
Colorectal Cancer
Recruiting NCT07136922
First in Human Safety and Ease of Use Assessment of 400mg Progesterone Callavid in Women With Luteal Phase Insufficiency
Luteal Phase Insuffiency · Progesterone Delivery
Recruiting NCT07213791
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
Ovarian Neoplasms · Breast Neoplasms · Pancreatic Intraductal Neoplasms
Recruiting NCT07596654
The Impact of Surgical Treatment on Survival in Localized Small Cell Esophageal Cancer
Esophageal Carcinoma · Limited-Stage Small Cell Esophageal Carcinoma
Not yet recruiting NCT07750210
Study of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults With Type 1 Diabetes
MASLD · Type 1 Diabetes
Not yet recruiting NCT07750587
Predicting Response and Exposure Changes in Cirrhosis for Effectiveness
Liver Cirrhosis
Recruiting NCT06571474
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
Obesity · Non-Alcoholic Fatty Liver Disease · Diabetes Mellitus, Type 2
Recruiting NCT07606742
Delivery of a Culturally Tailored Exercise Training Intervention for Hispanics With Multiple Sclerosis
Multiple Sclerosis
Recruiting NCT07749326
Conventional Versus Stomach-Partitioning Gastrojejunostomy for Malignant Gastric Outlet Obstruction in Stage IV Gastric Cancer (KLASS 16)
Stomach Neoplasms · Gastric Outlet Obstruction · Palliative Surgery
Recruiting NCT07165028
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Metabolic Dysfunction-Associated Steatotic Liver Disease
Recruiting NCT07750951
Single-arm, Phase II Clinical Study Evaluating the Safety and Efficacy of Sintilimab Combined With IBI-310 and Chemotherapy as Neoadjuvant Therapy for Locally Advanced Rectal Cancer
MSI-H/dMMR Locally Advanced Rectal Adenocarcinoma
Enrolling by invitation NCT06276764
The LINFU® U.S. Registry in Patients With IPMN (Intraductal Papillary Mucinous Neoplasm of the Pancreas)
IPMN, Pancreatic · Pancreas Cancer · Pancreatic Cyst
Recruiting NCT07747779
Comparison of Hormonal Response to a Mixed-Meal Tolerance Test After Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy With Duodenojejunal Bypass in Patients With Super Morbid Obesity
Bariatric Surgery · Hormonal Response · Post Bariatric Hypoglycemia
Recruiting NCT07747688
Retrospective Analysis of Early Gastric Cancer Patients Based on Prospective Clinical Dataset
Early Gastric Cancer
Recruiting NCT07091617
Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer
Miscellaneous Neoplasm, Nos · Non-Neoplastic Condition, Nos
Recruiting NCT06080789
A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis
Acute Pancreatitis
Recruiting NCT07699939
Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma
Gastric Adenocarcinoma · Gastroesophageal Junction (GEJ) Adenocarcinoma
Enrolling by invitation NCT07746999
North Jersey Community Research Initiative (NJCRI) Study on Transgender Liver Health
HEPATITIS C (HCV)
Not yet recruiting NCT07748130
CoQ10 Effects on MDM Liver Fat Via FibroTouchI.
Mitochondrial Diabetes
Not yet recruiting NCT07748377
Increasing Breast and Colorectal Cancer Screening in the Community
Colorectal Neoplasms · Breast Neoplasms
Recruiting NCT07736989
Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery
Pain, Postoperative · Analgesia
Recruiting NCT05677490
mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma
Advanced Esophageal Adenocarcinoma · Advanced Gastric Adenocarcinoma · Advanced Gastroesophageal Junction Adenocarcinoma
Recruiting NCT05477277
Adverse Outcomes and Mortality in Liver Transplant
End Stage Liver DIsease · Sarcopenia · Sarcopenic Obesity
Not yet recruiting NCT07653594
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE)
Surgery · Stomach Cancer · Pancreas Cancer
Not yet recruiting NCT07209215
ctDNA-Informed Management of Early-Stage Rectal Cancer
Rectal Adenocarcinoma · Rectal Cancer · Early-stage Rectal Cancer
Not yet recruiting NCT06362187
VR Pilot for Pancreatitis
Chronic Pancreatitis · Recurrent Pancreatitis
Recruiting NCT07283939
Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
Ampulla of Vater Carcinoma · Appendix Carcinoma · Carcinoma of Unknown Primary With Gastrointestinal Profile
Recruiting NCT02886247
Pancreatic Cancer Registry: For Any Person With a Personal or Family History
Pancreatic Cancer, ATM, BRCA, Hereditary Cancer
Not yet recruiting NCT07746518
A Phase III Clinical Trial and Extension Study to Evaluate the Efficacy and Safety of DWP14012 for Maintenance Therapy in Patients With Healed Erosive Esophagitis
Healed Erosive Esophagitis
Not yet recruiting NCT07748481
Comparison of the Therapeutic Efficacy of Non-touch Microwave Ablation, Tumor-puncture Microwave Ablation and Surgical Resection for Subcapsular Hepatocellular Carcinoma
Hepatocellular Carcinoma (HCC)
Not yet recruiting NCT07642492
REcovery After Cancer Application
Oesophageal Cancer · Gastric Cancer (Diagnosis)
Recruiting NCT06862115
The Effect of Discontinuation of Renin Angiotensin System Inhibitors on the Perioperative Myocardial Injury in Adult Patients Undergoing Colorectal Cancer Surgery
Myocardium; Injury · Perioperative/Postoperative Complications · Angiotensin-Converting-Enzyme Inhibitor
Not yet recruiting NCT07746830
Prospective Assessment of Alignment Between Multimodal Artificial Intelligence and Multidisciplinary Team Decisions in Gastrointestinal Oncology
Gastric Cancer · Colorectal Cancer · Gastrointestinal Cancer
Recruiting NCT05771675
Simvastatin Treatment to Improve Patient-reported Outcomes in Patients With Chronic Pancreatitis
Recurrent Acute Pancreatitis · Chronic Pancreatitis
Not yet recruiting NCT07522177
Animated Storytelling to Promote Colorectal Cancer Screening
Colorectal Cancer Screening
Recruiting NCT07143487
Family Communications After Genetic Testing
Colon Adenocarcinoma · Colorectal Adenocarcinoma · Rectal Adenocarcinoma
Recruiting NCT05673148
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
Metastatic Colorectal Adenocarcinoma · Stage IV Colorectal Cancer AJCC v8
Recruiting NCT07400289
Development of a FibroScan Liver Examination Using a Single Probe
Liver Diseases
Recruiting NCT06318169
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis